Nasal Spray Influenza Vaccine Global Market Report 2025

The nasal spray influenza vaccine market size has grown rapidly in recent years. It will grow from $1.31 billion in 2024 to $1.49 billion in 2025 at a compound annual growth rate (CAGR) of 13.2%. The growth during the historic period can be attributed to factors such as improved vaccine accessibility, heightened awareness of flu prevention, a growing emphasis on pediatric vaccination, higher vaccination rates, and a greater preference for needle-free vaccines.

The nasal spray influenza vaccine market size is expected to see rapid growth in the next few years. It will grow to $2.43 billion in 2029 at a compound annual growth rate (CAGR) of 13.1%. The growth during the forecast period is expected to be driven by factors such as a rising demand for convenient immunization, an increase in seasonal influenza cases, more government initiatives and support, projected growth in geriatric and high-risk populations, and greater adoption of vaccines in healthcare settings. Key trends during this period include innovations in vaccine delivery systems, the integration of mucosal immunity strategies, technological advancements in viral vector platforms, progress in cold-chain technology, and the incorporation of mRNA technology.

The growing prevalence of influenza is expected to drive the market for nasal spray influenza vaccines in the future. Influenza is a highly contagious viral infection that mainly affects the respiratory system, causing symptoms such as fever, cough, sore throat, body aches, and fatigue. The rise in influenza cases is largely due to the frequent genetic mutations of the virus, allowing it to escape existing immunity and spread quickly through populations. The nasal spray influenza vaccine helps protect against the virus by delivering a weakened form directly into the nasal passages, where the virus typically enters, prompting an immune response. For example, in June 2024, the UK Health Security Agency reported that between week 40 of 2022 and week 15 of 2023, 1,681 confirmed influenza-related critical care admissions were recorded by 108 NHS trusts in England. This was a significant increase compared to 182 admissions the previous season. As a result, the growing prevalence of influenza is contributing to the expansion of the nasal spray influenza vaccine market.

Companies operating in the nasal spray influenza vaccine market are focusing on creating innovative formulations, such as live attenuated influenza vaccines (LAIV), to enhance immune response and improve patient adherence. A live attenuated influenza vaccine is made from live, weakened viruses that stimulate the immune system to produce antibodies, offering protection without causing the disease. This type of vaccine generates a stronger immune response through both local and systemic immunity, which boosts the body’s defense against future flu infections. For example, in September 2024, AstraZeneca received approval from the U.S. Food and Drug Administration (FDA) for FluMist, a live attenuated influenza vaccine (LAIV). This vaccine can be self-administered by adults up to 49 years old or administered by caregivers to children between 2 and 17 years old, making it the first influenza vaccine in the U.S. approved for self- or caregiver-administration. The approval followed extensive usability studies that showed 100% of participants successfully delivered the full dose as instructed.

In October 2023, Mylab Discovery Solutions, an India-based biotechnology company, partnered with the Serum Institute of India to launch Nasovac S4, India’s first nasal influenza vaccine. Through this collaboration, the two companies aim to provide comprehensive protection against various influenza strains with Nasovac S4, a needle-free nasal vaccine. Serum Institute of India is a biotechnology company specializing in nasal influenza vaccines such as Nasovac-S and Nasovac-S4.

Major players in the nasal spray influenza vaccine market are Sanofi Pasteur SA, AstraZeneca PLC, GSK plc, Moderna Inc., CSL Limited, Sinovac Biotech Ltd., Emergent BioSolutions Inc., Serum Institute of India Pvt. Ltd., Beijing Wantai Biological Pharmacy Enterprise Co. Ltd., NPO Microgen JSC, Changchun BCHT Biotechnology Co. Ltd., Mitsubishi Tanabe Pharma Corporation, FluGen Inc., BioDiem Ltd, Starpharma Holdings Limited, Codagenix Inc., Nobilon International B.V., KM Biologics Co. Ltd., Altimmune Inc., Mylab Discovery Solutions Private Limited.

North America was the largest region in the nasal spray influenza vaccine market in 2024. Asia Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in this report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the nasal spray influenza vaccine market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The nasal spray influenza vaccine is a needle-free flu vaccine delivered through the nose, utilizing live attenuated viruses to provide protection against seasonal influenza. It is administered by spraying into the nostrils, where it triggers an immune response in the nasal passages to defend against the flu.

The primary types of nasal spray influenza vaccines are the live attenuated influenza vaccine (LAIV) and the inactivated influenza vaccine. LAIV is a needle-free flu vaccine that uses weakened live viruses to stimulate strong systemic and mucosal immune responses. These vaccines can be administered in single-dose or multi-dose formats and are designed for various age groups, including children, adults, and older adults. Distribution channels include hospitals, clinics, pharmacies, online stores, and other points of sale. End users of nasal spray influenza vaccines consist of healthcare providers, individuals, government health agencies, and pharmaceutical companies.

The nasal spray influenza vaccines market research report is one of a series of new reports that provides nasal spray influenza vaccines market statistics, including nasal spray influenza vaccines industry global market size, regional shares, competitors with a nasal spray influenza vaccines market share, nasal spray influenza vaccines market segments, market trends, and opportunities, and any further data you may need to thrive in the nasal spray influenza vaccines industry. This nasal spray influenza vaccines market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The nasal spray influenza vaccine market consists of sales of flumist quadrivalent, fluenz tetra, vaxinate, centripetal flu nasal spray vaccine, nasovac-s, fluvac nasal spray, and live attenuated influenza vaccine. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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