The normothermic machine perfusion market size has grown rapidly in recent years. It will grow from $1.48 billion in 2025 to $1.72 billion in 2026 at a compound annual growth rate (CAGR) of 16.2%. The growth in the historic period can be attributed to limited organ preservation technologies, dependence on cold storage methods, shortage of transplantable organs, increasing organ transplant procedures, early adoption of stationary perfusion machines.
The normothermic machine perfusion market size is expected to see rapid growth in the next few years. It will grow to $3.12 billion in 2030 at a compound annual growth rate (CAGR) of 16%. The growth in the forecast period can be attributed to development of portable and battery-operated machines, advancements in mechanical circulation and oxygenation technologies, rising organ transplantation demand globally, integration with smart monitoring systems, expansion of r&d in organ preservation. Major trends in the forecast period include rising adoption of portable normothermic machines, growing focus on organ viability and extended preservation, integration of advanced monitoring and oxygenation technologies, expansion of organ transplantation programs, increasing use in research and development applications.
The growing demand for organ transplantation is expected to drive the expansion of the normothermic machine perfusion market. Organ transplantation involves replacing a malfunctioning or diseased organ with a healthy one from a donor. The increasing need for transplants is fueled by the rising prevalence of end-stage organ failure, often due to chronic diseases, as well as advancements in surgical techniques and immunosuppressive therapies. Normothermic machine perfusion plays a critical role in preserving and reviving donor organs by maintaining them at body temperature with oxygenated blood or a perfusate until they are transplanted. For example, in January 2024, the U.S. Department of Health & Human Services reported that 46,632 organ transplants were performed in 2023, marking an 8.7% increase over 2022. This growing demand for organ transplants is driving market growth for normothermic machine perfusion.
Key players in the normothermic machine perfusion market are concentrating on establishing advanced research facilities to foster innovation, enhance organ preservation technologies, and improve transplant outcomes. Expanding these facilities boosts the capacity for organ preservation, research, and clinical application, which in turn enhances both transplant success rates and availability. For example, in May 2024, OrganOx Ltd., a UK-based medical equipment company, opened a new 18,000 sq. ft. research and development facility in Oxford. This expansion is aimed at advancing innovation and fostering partnerships, building on the success of its Metra device, which has improved liver transplant outcomes worldwide. The company remains optimistic about advancing both scientific and clinical innovations through technology to better address organ failure.
In March 2025, OrganOx Ltd. partnered with ProCure On Demand Ltd. to enhance donor liver recovery and evaluation for transplantation. By combining OrganOx’s normothermic machine perfusion system with ProCure’s skilled surgical team and extensive service network, the collaboration aims to provide flexible, comprehensive solutions tailored to the specific needs of transplant centers, ultimately improving transplant efficiency and patient outcomes. ProCure On Demand is a U.S.-based healthcare company specializing in human organ transplantation.
Major companies operating in the normothermic machine perfusion market are TransMedics Inc., OrganOx Limited, XVIVO Perfusion AB, Organ Recovery Systems Inc., Bridge to Life Ltd., Paragonix Technologies Inc., Lifeline Scientific Inc., LifePort Inc., XENIOS AG, Lung Bioengineering Inc., Waters Medical Systems LLC, Organ Assist B.V., Preservation Solutions Inc., Perfusix AB, Fluent Medical Inc., HemoTherapeutics Inc., Revivicor Inc., Transplant Solutions Inc., BioMedica Diagnostics (Organ Perfusion Division), Advanced Perfusion Systems Inc., Organ Preservation Alliance Technologies, NormaTech Medical Systems.
North America was the largest region in the normothermic machine perfusion market in 2025. The regions covered in the normothermic machine perfusion market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the normothermic machine perfusion market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
Tariffs are impacting the normothermic machine perfusion market by increasing the cost of imported perfusion devices, monitoring sensors, and oxygenation components. Segments like portable and advanced stationary machines are particularly impacted, with regions including Asia-Pacific and Europe experiencing higher import duties. This has led to higher procurement costs and slowed adoption in some hospitals and specialty clinics. However, tariffs have also encouraged local manufacturing, innovation in device design, and development of cost-optimized solutions for domestic markets.
The normothermic machine perfusion market research report is one of a series of new reports that provides normothermic machine perfusion market statistics, including normothermic machine perfusion industry global market size, regional shares, competitors with a normothermic machine perfusion market share, detailed normothermic machine perfusion market segments, market trends and opportunities, and any further data you may need to thrive in the normothermic machine perfusion industry. This normothermic machine perfusion market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
Normothermic machine perfusion is a preservation method where organs are kept at normal body temperature (around 37°C) and provided with oxygenated blood or perfusate to replicate physiological conditions. This technique supports improved organ viability, functional assessment, and extended preservation time before transplantation.
The primary products in normothermic machine perfusion include portable and stationary normothermic machines. Portable devices are compact, mobile systems designed to preserve donor organs at a body temperature of around 37°C during transportation. These machines function using various advanced technologies, such as mechanical circulation, oxygenation systems, and monitoring systems. Major applications include organ preservation, transplantation, and research and development, with use spanning hospitals, ambulatory surgery centers (ASCs), specialty clinics, and other healthcare settings.
The normothermic machine perfusion market includes revenues earned by entities by providing services such as organ viability assessment, logistics and transport solutions, and organ repair and reconditioning. The market value includes the value of related goods sold by the service provider or included within the service offering. The normothermic machine perfusion market also includes sales of perfusion systems, kits, bioreactors, sensors, and monitoring systems. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
This product will be delivered within 1-3 business days.
The normothermic machine perfusion market size is expected to see rapid growth in the next few years. It will grow to $3.12 billion in 2030 at a compound annual growth rate (CAGR) of 16%. The growth in the forecast period can be attributed to development of portable and battery-operated machines, advancements in mechanical circulation and oxygenation technologies, rising organ transplantation demand globally, integration with smart monitoring systems, expansion of r&d in organ preservation. Major trends in the forecast period include rising adoption of portable normothermic machines, growing focus on organ viability and extended preservation, integration of advanced monitoring and oxygenation technologies, expansion of organ transplantation programs, increasing use in research and development applications.
The growing demand for organ transplantation is expected to drive the expansion of the normothermic machine perfusion market. Organ transplantation involves replacing a malfunctioning or diseased organ with a healthy one from a donor. The increasing need for transplants is fueled by the rising prevalence of end-stage organ failure, often due to chronic diseases, as well as advancements in surgical techniques and immunosuppressive therapies. Normothermic machine perfusion plays a critical role in preserving and reviving donor organs by maintaining them at body temperature with oxygenated blood or a perfusate until they are transplanted. For example, in January 2024, the U.S. Department of Health & Human Services reported that 46,632 organ transplants were performed in 2023, marking an 8.7% increase over 2022. This growing demand for organ transplants is driving market growth for normothermic machine perfusion.
Key players in the normothermic machine perfusion market are concentrating on establishing advanced research facilities to foster innovation, enhance organ preservation technologies, and improve transplant outcomes. Expanding these facilities boosts the capacity for organ preservation, research, and clinical application, which in turn enhances both transplant success rates and availability. For example, in May 2024, OrganOx Ltd., a UK-based medical equipment company, opened a new 18,000 sq. ft. research and development facility in Oxford. This expansion is aimed at advancing innovation and fostering partnerships, building on the success of its Metra device, which has improved liver transplant outcomes worldwide. The company remains optimistic about advancing both scientific and clinical innovations through technology to better address organ failure.
In March 2025, OrganOx Ltd. partnered with ProCure On Demand Ltd. to enhance donor liver recovery and evaluation for transplantation. By combining OrganOx’s normothermic machine perfusion system with ProCure’s skilled surgical team and extensive service network, the collaboration aims to provide flexible, comprehensive solutions tailored to the specific needs of transplant centers, ultimately improving transplant efficiency and patient outcomes. ProCure On Demand is a U.S.-based healthcare company specializing in human organ transplantation.
Major companies operating in the normothermic machine perfusion market are TransMedics Inc., OrganOx Limited, XVIVO Perfusion AB, Organ Recovery Systems Inc., Bridge to Life Ltd., Paragonix Technologies Inc., Lifeline Scientific Inc., LifePort Inc., XENIOS AG, Lung Bioengineering Inc., Waters Medical Systems LLC, Organ Assist B.V., Preservation Solutions Inc., Perfusix AB, Fluent Medical Inc., HemoTherapeutics Inc., Revivicor Inc., Transplant Solutions Inc., BioMedica Diagnostics (Organ Perfusion Division), Advanced Perfusion Systems Inc., Organ Preservation Alliance Technologies, NormaTech Medical Systems.
North America was the largest region in the normothermic machine perfusion market in 2025. The regions covered in the normothermic machine perfusion market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the normothermic machine perfusion market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
Tariffs are impacting the normothermic machine perfusion market by increasing the cost of imported perfusion devices, monitoring sensors, and oxygenation components. Segments like portable and advanced stationary machines are particularly impacted, with regions including Asia-Pacific and Europe experiencing higher import duties. This has led to higher procurement costs and slowed adoption in some hospitals and specialty clinics. However, tariffs have also encouraged local manufacturing, innovation in device design, and development of cost-optimized solutions for domestic markets.
The normothermic machine perfusion market research report is one of a series of new reports that provides normothermic machine perfusion market statistics, including normothermic machine perfusion industry global market size, regional shares, competitors with a normothermic machine perfusion market share, detailed normothermic machine perfusion market segments, market trends and opportunities, and any further data you may need to thrive in the normothermic machine perfusion industry. This normothermic machine perfusion market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
Normothermic machine perfusion is a preservation method where organs are kept at normal body temperature (around 37°C) and provided with oxygenated blood or perfusate to replicate physiological conditions. This technique supports improved organ viability, functional assessment, and extended preservation time before transplantation.
The primary products in normothermic machine perfusion include portable and stationary normothermic machines. Portable devices are compact, mobile systems designed to preserve donor organs at a body temperature of around 37°C during transportation. These machines function using various advanced technologies, such as mechanical circulation, oxygenation systems, and monitoring systems. Major applications include organ preservation, transplantation, and research and development, with use spanning hospitals, ambulatory surgery centers (ASCs), specialty clinics, and other healthcare settings.
The normothermic machine perfusion market includes revenues earned by entities by providing services such as organ viability assessment, logistics and transport solutions, and organ repair and reconditioning. The market value includes the value of related goods sold by the service provider or included within the service offering. The normothermic machine perfusion market also includes sales of perfusion systems, kits, bioreactors, sensors, and monitoring systems. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
This product will be delivered within 1-3 business days.
Table of Contents
1. Executive Summary
2. Normothermic Machine Perfusion Market Characteristics
3. Normothermic Machine Perfusion Market Supply Chain Analysis
4. Global Normothermic Machine Perfusion Market Trends and Strategies
5. Normothermic Machine Perfusion Market Analysis of End Use Industries
7. Global Normothermic Machine Perfusion Strategic Analysis Framework, Current Market Size, Market Comparisons and Growth Rate Analysis
8. Global Normothermic Machine Perfusion Total Addressable Market (TAM) Analysis for the Market
9. Normothermic Machine Perfusion Market Segmentation
10. Normothermic Machine Perfusion Market Regional and Country Analysis
11. Asia-Pacific Normothermic Machine Perfusion Market
12. China Normothermic Machine Perfusion Market
13. India Normothermic Machine Perfusion Market
14. Japan Normothermic Machine Perfusion Market
15. Australia Normothermic Machine Perfusion Market
16. Indonesia Normothermic Machine Perfusion Market
17. South Korea Normothermic Machine Perfusion Market
18. Taiwan Normothermic Machine Perfusion Market
19. South East Asia Normothermic Machine Perfusion Market
20. Western Europe Normothermic Machine Perfusion Market
21. UK Normothermic Machine Perfusion Market
22. Germany Normothermic Machine Perfusion Market
23. France Normothermic Machine Perfusion Market
24. Italy Normothermic Machine Perfusion Market
25. Spain Normothermic Machine Perfusion Market
26. Eastern Europe Normothermic Machine Perfusion Market
27. Russia Normothermic Machine Perfusion Market
28. North America Normothermic Machine Perfusion Market
29. USA Normothermic Machine Perfusion Market
30. Canada Normothermic Machine Perfusion Market
31. South America Normothermic Machine Perfusion Market
32. Brazil Normothermic Machine Perfusion Market
33. Middle East Normothermic Machine Perfusion Market
34. Africa Normothermic Machine Perfusion Market
36. Normothermic Machine Perfusion Market Competitive Landscape and Company Profiles
37. Normothermic Machine Perfusion Market Other Major and Innovative Companies
40. Normothermic Machine Perfusion Market High Potential Countries, Segments and Strategies
41. Appendix
List of Tables
Executive Summary
Normothermic Machine Perfusion Market Global Report 2026 provides strategists, marketers and senior management with the critical information they need to assess the market.This report focuses normothermic machine perfusion market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
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Description
Where is the largest and fastest growing market for normothermic machine perfusion? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The normothermic machine perfusion market global report answers all these questions and many more.The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, total addressable market (TAM), market attractiveness score (MAS), competitive landscape, market shares, company scoring matrix, trends and strategies for this market. It traces the market’s historic and forecast market growth by geography.
- The market characteristics section of the report defines and explains the market. This section also examines key products and services offered in the market, evaluates brand-level differentiation, compares product features, and highlights major innovation and product development trends.
- The supply chain analysis section provides an overview of the entire value chain, including key raw materials, resources, and supplier analysis. It also provides a list competitor at each level of the supply chain.
- The updated trends and strategies section analyses the shape of the market as it evolves and highlights emerging technology trends such as digital transformation, automation, sustainability initiatives, and AI-driven innovation. It suggests how companies can leverage these advancements to strengthen their market position and achieve competitive differentiation.
- The regulatory and investment landscape section provides an overview of the key regulatory frameworks, regularity bodies, associations, and government policies influencing the market. It also examines major investment flows, incentives, and funding trends shaping industry growth and innovation.
- The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
- The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.
- The total addressable market (TAM) analysis section defines and estimates the market potential compares it with the current market size, and provides strategic insights and growth opportunities based on this evaluation.
- The market attractiveness scoring section evaluates the market based on a quantitative scoring framework that considers growth potential, competitive dynamics, strategic fit, and risk profile. It also provides interpretive insights and strategic implications for decision-makers.
- Market segmentations break down the market into sub markets.
- The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth.
- Expanded geographical coverage includes Taiwan and Southeast Asia, reflecting recent supply chain realignments and manufacturing shifts in the region. This section analyzes how these markets are becoming increasingly important hubs in the global value chain.
- The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
- The company scoring matrix section evaluates and ranks leading companies based on a multi-parameter framework that includes market share or revenues, product innovation, and brand recognition.
Report Scope
Markets Covered:
1) By Product Type: Portable Normothermic Machine; Stationary Normothermic Machine2) By Technology: Mechanical Circulation Technology; Oxygenation Technology; Monitoring Technology
3) By Application: Organ Preservation; Organ Transplantation; Research And Development
4) By End-User: Hospitals And Ambulatory Surgery Centers (ASCs); Specialty Clinics; Other End-Users
Subsegments:
1) By Portable Normothermic Machine: Compact Portable; Battery-Operated Portable Machines; Transport-Friendly Portable Units2) By Stationary Normothermic Machine: In-Hospital Stationary Machines; Modular Stationary Systems; Advanced Fixed-Location Units
Companies Mentioned: TransMedics Inc.; OrganOx Limited; XVIVO Perfusion AB; Organ Recovery Systems Inc.; Bridge to Life Ltd.; Paragonix Technologies Inc.; Lifeline Scientific Inc.; LifePort Inc.; XENIOS AG; Lung Bioengineering Inc.; Waters Medical Systems LLC; Organ Assist B.V.; Preservation Solutions Inc.; Perfusix AB; Fluent Medical Inc.; HemoTherapeutics Inc.; Revivicor Inc.; Transplant Solutions Inc.; BioMedica Diagnostics (Organ Perfusion Division); Advanced Perfusion Systems Inc.; Organ Preservation Alliance Technologies; NormaTech Medical Systems
Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Taiwan; Russia; South Korea; UK; USA; Canada; Italy; Spain
Regions: Asia-Pacific; South East Asia; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
Time Series: Five years historic and ten years forecast.
Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita.
Data Segmentation: Country and regional historic and forecast data, market share of competitors, market segments.
Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.
Delivery Format: Word, PDF or Interactive Report + Excel Dashboard
Added Benefits:
- Bi-Annual Data Update
- Customisation
- Expert Consultant Support
Companies Mentioned
The companies featured in this Normothermic Machine Perfusion market report include:- TransMedics Inc.
- OrganOx Limited
- XVIVO Perfusion AB
- Organ Recovery Systems Inc.
- Bridge to Life Ltd.
- Paragonix Technologies Inc.
- Lifeline Scientific Inc.
- LifePort Inc.
- XENIOS AG
- Lung Bioengineering Inc.
- Waters Medical Systems LLC
- Organ Assist B.V.
- Preservation Solutions Inc.
- Perfusix AB
- Fluent Medical Inc.
- HemoTherapeutics Inc.
- Revivicor Inc.
- Transplant Solutions Inc.
- BioMedica Diagnostics (Organ Perfusion Division)
- Advanced Perfusion Systems Inc.
- Organ Preservation Alliance Technologies
- NormaTech Medical Systems
Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 250 |
| Published | February 2026 |
| Forecast Period | 2026 - 2030 |
| Estimated Market Value ( USD | $ 1.72 Billion |
| Forecasted Market Value ( USD | $ 3.12 Billion |
| Compound Annual Growth Rate | 16.0% |
| Regions Covered | Global |
| No. of Companies Mentioned | 23 |
