Sepsis Therapeutics Global Market Report 2025

The sepsis therapeutics market size has grown rapidly in recent years. It will grow from $4.03 billion in 2024 to $4.43 billion in 2025 at a compound annual growth rate (CAGR) of 9.9%. The growth observed in the historical period can be credited to factors such as the rising number of sepsis cases, heightened awareness surrounding early diagnosis and treatment, progress in antibiotic and antifungal therapies, increased healthcare spending, and regulatory backing for the advancement of sepsis treatments.

The sepsis therapeutics market size is expected to see strong growth in the next few years. It will grow to $6.41 billion in 2029 at a compound annual growth rate (CAGR) of 9.7%. The projected growth in the forecast period is driven by factors such as the increasing prevalence of antimicrobial resistance, greater adoption of biomarker-based diagnostics, a growing emphasis on immunotherapy for sepsis treatment, expansion of hospital infrastructure in developing markets, and government efforts to enhance sepsis management. Key trends during this period include the development of precision medicine, integration of AI for early sepsis detection, a rise in combination therapies, an increase in clinical trials for new sepsis drugs, and an expanded use of rapid molecular diagnostics.

The growing prevalence of infectious diseases is expected to drive the sepsis therapeutics market forward. Infectious diseases, caused by harmful microorganisms such as bacteria, viruses, fungi, or parasites, are on the rise, primarily due to climate change. Changing temperatures and ecosystems are expanding the habitats of disease-carrying vectors such as mosquitoes, leading to the spread of illnesses such as malaria and dengue fever. Sepsis therapeutics address these infectious diseases by targeting the infection itself, reducing inflammation, and supporting organ function to prevent life-threatening complications. According to the National Library of Medicine, in January 2023, infectious diseases are responsible for over 52 million deaths annually, with nearly half of the global population at risk. Each year, approximately 14 million children under five die, and 70% of these deaths are linked to preventable diseases that could be avoided through vaccination. Thus, the increasing prevalence of infectious diseases is a key factor driving the growth of the sepsis therapeutics market.

Companies in the sepsis diagnostics market are focused on developing innovative diagnostic technologies to improve sepsis detection and management. Advances in rapid molecular tests, which can detect pathogens quickly and accurately, are crucial for early diagnosis, better patient outcomes, and reduced mortality rates caused by delayed detection. These rapid molecular tests use advanced techniques such as PCR or isothermal amplification to identify pathogens by detecting their genetic material. For example, in November 2023, Inflammatix Inc., a US-based biotechnology company, announced the completion of its TriVerity Acute Infection and Sepsis Test System. This system includes the Myrna Instrument and the TriVerity Cartridge, designed for emergency department use to assess the likelihood of bacterial or viral infections and the risk of acute decompensation in patients with suspected infections and sepsis.

In January 2025, Partner Therapeutics, Inc. (PTx), a US-based biotechnology company specializing in sepsis therapeutics, partnered with the Biomedical Advanced Research and Development Authority (BARDA) to fund a Phase 2 study on the safety and optimal dosing of LEUKINE (sargramostim, rhu GM-CSF) in sepsis patients. This collaboration aims to enhance sepsis treatment by developing tools to measure immune status, enabling more targeted immunomodulatory therapies. BARDA, a US government department dedicated to biomedical advanced research, is supporting this initiative.

Major players in the sepsis therapeutics market are Pfizer Inc., AstraZeneca plc, GSK plc, Eli Lilly and Company, Viatris Inc., Astellas Pharma Inc., inthelia, La Jolla Pharmaceutical Co., Cytovale Inc., Aridis Pharmaceuticals Inc., Partner Therapeutics Inc., T2 Biosystems Inc., Modus Therapeutics, InflaRx GmbH, Adrenomed AG, Sepsia Therapeutics, Endpoint Health, Prenosis Inc., Spectral Medical Inc, Matisse Pharmaceuticals B.V.

North America was the largest region in the sepsis therapeutics market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in sepsis therapeutics report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the sepsis therapeutics market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Sepsis therapeutics refer to the medical treatments and medications specifically aimed at managing sepsis, a life-threatening condition triggered by the body's extreme response to infection. The primary objective of these treatments is to control the infection, sustain vital functions, manage inflammation, and avert organ failure, thereby enhancing survival rates and aiding in patient recovery.

The key drug categories used in sepsis treatment include cephalosporins, aminoglycosides, glycopeptides, among others. Cephalosporins, a class of broad-spectrum antibiotics, are frequently prescribed for sepsis and other serious bacterial infections. These drugs can be administered through various methods, such as orally, via injection, or topically. They are distributed through different channels, including hospital pharmacies, retail pharmacies, and online platforms. These medications are primarily used in settings such as hospitals, clinics, and other healthcare environments.

The sepsis therapeutics market research report is one of a series of new reports that provides sepsis therapeutics market statistics, including the sepsis therapeutics industry global market size, regional shares, competitors with the sepsis therapeutics market share, detailed sepsis therapeutics market segments, market trends, and opportunities, and any further data you may need to thrive in the sepsis therapeutics industry. This sepsis therapeutics market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The sepsis therapeutics market consists of revenues earned by entities providing services such as pharmaceutical interventions, supportive therapies, and diagnostic solutions. The market value includes the value of related goods sold by the service provider or included within the service offering. The sepsis therapeutics market also includes sales of antibiotics, intravenous fluids, vasopressors, and advanced therapies aimed at controlling infection, stabilizing patients, and preventing organ failure. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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