Total Ankle Replacement Global Market Report 2025

The total ankle replacement market size has grown strongly in recent years. It will grow from $0.92 billion in 2024 to $1 billion in 2025 at a compound annual growth rate (CAGR) of 7.9%. The growth during the historic period can be attributed to rising healthcare expenditures globally, greater availability of insurance and reimbursement for TAR procedures, increased investments in orthopedic research and development, a surge in venture capital funding for medtech startups, and growing patient awareness of TAR as a treatment option.

The total ankle replacement market size is expected to see strong growth in the next few years. It will grow to $1.33 billion in 2029 at a compound annual growth rate (CAGR) of 7.5%. The projected growth in the forecast period is driven by the aging global population, increasing prevalence of arthritis, rising obesity rates, a growing incidence of sports-related injuries, and an increase in the physically active elderly population. Key trends expected include advancements in total ankle implant designs, improved surgical techniques and instrumentation, better clinical outcomes and longer implant lifespans, the development of minimally invasive TAR techniques, and the creation of custom, patient-specific implants.

The growing prevalence of arthritis is expected to drive the growth of the total ankle replacement market. Arthritis is a group of conditions causing inflammation, pain, stiffness, and swelling in the joints, often leading to reduced mobility and joint function. The rise in arthritis cases is largely due to an aging population, as increased life expectancy results in greater joint wear and degeneration, making older adults more susceptible to the disease. Total ankle replacement is often needed for severe arthritis, as joint damage can lead to chronic pain and loss of mobility, and replacing the joint helps restore function and alleviate discomfort. For example, in March 2023, the Office for Health Improvement and Disparities, a UK-based government department, reported that 17.6% of adults aged 16 and over had a chronic musculoskeletal (MSK) ailment, such as arthritis, in 2022, up from 17% in 2021. Thus, the increasing prevalence of arthritis is fueling the growth of the total ankle replacement market.

Companies in the total ankle replacement market are focusing on developing advanced solutions, such as mobile bearing ankle systems, to improve joint stability and enhance patient mobility. Mobile bearing ankle systems are prosthetic implants where the bearing surface moves relative to the tibia, allowing for more natural motion and better joint functionality, often leading to improved mobility and reduced wear compared to fixed bearing systems. For example, in August 2024, Enovis Corporation, a US-based medical technology company, launched the Scandinavian Total Ankle Replacement (STAR Ankle) with e+ Polyethylene. This material resists oxidation, maintains stable wear rates, and ensures mechanical strength over time. The non-cemented design provides 225 patient-matched configurations, offering greater flexibility and reducing bone stress. The new e+ Polyethylene improves durability and integrates with patient-specific instrumentation (PSI) for more precise surgical planning.

In June 2022, Conmed Corporation, a US-based medical technology company, acquired In2Bones Global Inc. for an undisclosed amount. This acquisition allowed CONMED to expand its orthopedic portfolio, gaining access to the growing extremities market and broadening its global orthopedic offerings. In2Bones Global Inc. is a US-based manufacturer of total ankle systems.

Major players in the total ankle replacement market are Johnson And Johnson Services Inc., Stryker Corporation, Zimmer Biomet Holdings Inc., Smith And Nephew plc, Enovis Corporation, Integra LifeSciences Holdings Corporation, DJO LLC, Conmed Corporation, Wright Medical Group N.V., Exactech Inc., Corin Group PLC, MicroPort Orthopedics Inc., Paragon 28 Inc., Allegra Orthopaedics Limited, FH Orthopedics, Vilex LLC, XLO Inc., restor3d Inc., BioPro Inc., and MatOrtho Limited.

North America was the largest region in the total ankle replacement market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in total ankle replacement report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the total ankle replacement market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Total ankle replacement (TAR) is a surgical procedure where a damaged or arthritic ankle joint is removed and replaced with an artificial joint. The procedure aims to restore joint function, alleviate pain, and enhance mobility by mimicking the natural movement of the ankle. It involves resurfacing the tibia and talus bones and inserting prosthetic components that allow for controlled motion and weight-bearing.

The primary product types for total ankle replacement include fixed-bearing total ankle replacement systems, mobile-bearing total ankle replacement systems, and bionic ankle replacement systems. Fixed-bearing total ankle replacement systems are implants where the polyethylene insert is securely attached to the metal tibial component, providing stable articulation with the talar component and restricting motion between the components. These systems use materials such as metal, plastic, and ceramic and are employed across various surgical approaches, including anterior, posterior, lateral, and minimally invasive approaches. The key end users include hospitals, ambulatory surgical centers, orthopedic clinics, and rehabilitation centers.

The total ankle replacement market research report is one of a series of new reports that provides total ankle replacement market statistics, including total ankle replacement industry global market size, regional shares, competitors with a total ankle replacement market share, detailed total ankle replacement market segments, market trends and opportunities, and any further data you may need to thrive in the total ankle replacement industry. This total ankle replacement market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The total ankle replacement market consists of revenues earned by entities by providing services such as preoperative planning support, intraoperative technical assistance, custom implant design services, and 3d preoperative modeling. The market value includes the value of related goods sold by the service provider or included within the service offering. The total ankle replacement market also includes sales of ankle fusion systems, ankle revision systems, instrumentation kits, and bone graft materials. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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