Pain Management Global Market Report 2025

The pain management market size has grown steadily in recent years. It will grow from $73.77 billion in 2024 to $77.3 billion in 2025 at a compound annual growth rate (CAGR) of 4.8%. Factors contributing to this historical growth include improved disposable income levels, enhanced healthcare infrastructure, a rising prevalence of diseases linked to modern lifestyles, increased use of minimally invasive and non-opioid pain therapies, and heightened awareness about managing pain effectively.

The pain management market size is expected to see steady growth in the next few years. It will grow to $92.09 billion in 2029 at a compound annual growth rate (CAGR) of 4.5%. This anticipated growth is supported by the growing need for long-term pain relief, a larger aging population, expanded healthcare services, improved education about pain care, and government programs aimed at strengthening healthcare systems. Key trends expected to influence the market include the rise of sophisticated healthcare technologies, innovations in pain treatment methods, the use of virtual reality (VR) in therapy, the adoption of digital therapeutics (DTx), and the shift toward non-opioid painkillers.

The growing prevalence of chronic pain conditions is anticipated to drive the expansion of the pain management market. Chronic pain is defined as persistent discomfort lasting more than three months and often continues beyond the normal healing time of an injury or illness. This increase in chronic pain cases is largely linked to rising obesity rates, as excess body weight puts added stress on joints and muscles, resulting in conditions like osteoarthritis and lower back pain. Pain management addresses chronic pain by offering targeted therapies that alleviate discomfort and improve the quality of life. These treatments provide personalized care plans, making daily tasks easier and enhancing overall well-being. For example, in March 2023, the Office for Health Improvement and Disparities in the UK reported that 17.6% of individuals aged 16 and older had a long-term musculoskeletal condition, such as arthritis or chronic back or joint problems, in 2022 - an increase from 17% in 2021. This rise in chronic pain cases is contributing to the growth of the pain management market.

Key players in the pain management market are increasingly investing in advanced drug formulations like transdermal drugs to improve targeted drug delivery, enhance patient adherence, and reduce adverse effects. Transdermal drugs are administered through the skin via patches, gels, or creams. In February 2025, Aveva Drug Delivery Systems Inc., a U.S.-based transdermal drug delivery company, introduced a generic fentanyl transdermal patch designed for three-day use to treat moderate to severe chronic pain. This product steadily delivers fentanyl, a powerful opioid analgesic, through the skin and into the bloodstream, providing consistent pain relief. The patch also includes features such as a secure adhesive for prolonged wear and a tamper-evident design to encourage safe use.

In October 2024, Stryker Corporation, a U.S.-based medical technology firm, acquired Vertos Medical Inc. in an effort to strengthen its non-surgical treatment offerings and expand its footprint in ambulatory surgery centers. This acquisition includes Vertos Medical’s minimally invasive mild procedure, aimed at enhancing chronic pain management. Vertos Medical is a U.S.-based medical device company focused on minimally invasive solutions for chronic pain.

Major players in the pain management market are Pfizer Inc., Johnson & Johnson, Merck & Co Inc., Bayer AG, Sanofi S.A., AstraZeneca PLC, Abbott Laboratories, Novartis AG, GlaxoSmithKline plc, Medtronic plc, Eli Lilly and Company, Becton, Dickinson and Company, Teva Pharmaceutical Industries Ltd, Boehringer Ingelheim International GmbH, Boston Scientific Corporation, Regeneron Pharmaceuticals Inc., Baxter International Inc., Mallinckrodt Pharmaceuticals plc, Purdue Pharma L.P., Nevro Corp.

North America was the largest region in the pain management market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in pain management report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the pain management market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Pain management is a medical specialty focused on identifying, addressing, and preventing pain to enhance a patient’s quality of life. It employs a range of methods and treatments aimed at managing both acute and chronic pain. The main goal of pain management is to relieve discomfort, restore functionality, and promote overall well-being.

Pain management treatments primarily include medications, physical therapy, and alternative methods. Medications are used to ease pain from mild to severe and encompass several types, such as non-steroidal anti-inflammatory drugs (NSAIDs), anticonvulsants, sedatives, narcotics, antimigraine agents, antidepressants, and others. These drugs are available through over-the-counter or prescription channels and are applied to treat various conditions like neuropathic pain, cancer-related pain, facial pain and migraines, musculoskeletal disorders, fibromyalgia, chronic back pain, joint pain, headaches, and postoperative discomfort. Key users of these treatments include hospitals and clinics, pharmaceutical and medical device companies, research and academic institutions, and others.

The pain management market research report is one of a series of new reports that provides pain management market statistics, including pain management industry global market size, regional shares, competitors with a pain management market share, pain management market segments, market trends and opportunities, and any further data you may need to thrive in the pain management industry. This pain management market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The pain management market includes revenues earned by entities through medication management, rehabilitation and psychological counseling, and interventional procedures. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.

The market value is defined as the revenues that enterprises gain from the sale of goods and services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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