Sarcopenia Treatment - Global Strategic Business Report

The global market for Sarcopenia Treatment was valued at US$3.0 Billion in 2024 and is projected to reach US$3.6 Billion by 2030, growing at a CAGR of 3.2% from 2024 to 2030. This comprehensive report provides an in-depth analysis of market trends, drivers, and forecasts, helping you make informed business decisions. The report includes the most recent global tariff developments and how they impact the Sarcopenia Treatment market.

Global Sarcopenia Treatment Market - Key Trends & Drivers Summarized

Why Is Sarcopenia Emerging as a Critical Target for Therapeutic Innovation in Aging Populations?

Sarcopenia, characterized by progressive skeletal muscle loss and functional impairment, is rapidly gaining attention as a standalone clinical entity rather than just a byproduct of aging. With growing awareness about frailty-related hospitalization risks, mobility decline, and the economic burden of elderly care, healthcare systems are increasingly prioritizing early detection and treatment of sarcopenia. The condition has been officially recognized by the ICD-10 coding system and is now included in geriatric risk assessments across the U.S., Europe, and Japan. This regulatory recognition is catalyzing clinical research, diagnostic development, and therapeutic intervention strategies tailored to sarcopenia’s unique pathophysiology.

Current treatment approaches are moving beyond nutritional supplementation and physical rehabilitation to include pharmacological agents that target muscle anabolism and mitochondrial function. Investigational therapies such as selective androgen receptor modulators (SARMs), myostatin inhibitors, and mitochondrial enhancers are under various stages of clinical evaluation. These candidates aim to promote muscle protein synthesis, reduce catabolism, and improve mitochondrial efficiency-all of which contribute to reversing or slowing the progression of sarcopenia. Moreover, several biotech startups are leveraging RNA-targeted platforms and metabolic modulators to develop first-in-class sarcopenia-specific drugs, reflecting a growing investor and research interest in this under-addressed condition.

How Are Diagnostic and Patient Stratification Advances Shaping Therapeutic Development?

The evolution of diagnostic modalities is significantly enhancing the precision and scope of sarcopenia treatment. Dual-energy X-ray absorptiometry (DXA), bioelectrical impedance analysis (BIA), and computed tomography (CT) scans are now being used not only for muscle mass quantification but also for longitudinal monitoring of therapy outcomes. Digital muscle function trackers and gait analysis tools are being integrated into clinical trials to generate more granular, real-world evidence on treatment efficacy. These diagnostics are enabling personalized treatment regimens, particularly in frail elderly populations with multiple comorbidities where a one-size-fits-all approach is ineffective.

Patient stratification based on inflammatory biomarkers, hormonal imbalances, and metabolic risk profiles is becoming integral to trial design and clinical practice. Chronic low-grade inflammation, insulin resistance, and deficiencies in testosterone or vitamin D are now recognized as key risk amplifiers of sarcopenia. Consequently, treatment approaches are being tailored to specific patient phenotypes-such as inflammatory sarcopenia or cachexia-linked muscle wasting in cancer patients. These advances are allowing pharmaceutical companies and research institutions to recruit more targeted patient cohorts and design mechanism-specific interventions, accelerating regulatory pathways and improving clinical success rates.

What Therapeutic Approaches Are Being Explored to Address This Multifactorial Condition?

The therapeutic pipeline for sarcopenia is expanding beyond basic muscle enhancement to include multifaceted strategies addressing neuromuscular coordination, metabolic regulation, and hormonal support. SARMs such as enobosarm (GTx-024) and MK-0773 have demonstrated promising anabolic effects in early trials, while myostatin pathway inhibitors like bimagrumab and anti-activin receptor antibodies are being tested for their ability to block muscle degradation signals. Additionally, metabolic agents such as metformin and mitochondrial biogenesis boosters are under investigation for their indirect benefits on muscle mass and strength.

Nutraceuticals and combination therapies are also gaining clinical traction. Formulations combining high-leucine whey protein, omega-3 fatty acids, and vitamin D are being evaluated in long-term studies to determine synergistic benefits. These combinations are particularly relevant in post-hospital recovery settings and among older adults with low dietary protein intake. Furthermore, neuromuscular electrical stimulation (NMES) devices and robotic rehabilitation systems are being introduced in sarcopenia care to augment physical therapy in patients with limited mobility. These hardware-based interventions are being paired with digital tracking apps to record performance, guide therapy adjustments, and ensure compliance.

What Factors Are Accelerating the Global Growth of Sarcopenia Treatment Options?

The growth in the sarcopenia treatment market is driven by several factors, including the rapidly aging global population, increased clinical recognition of sarcopenia as a disease, and the shift toward preventive geriatrics. As life expectancy rises, sarcopenia-related disability is emerging as a leading contributor to age-related health expenditures, particularly in countries like Japan, Italy, Germany, and South Korea. Health insurers and policy makers are supporting early intervention strategies by funding screening programs, nutritional subsidies, and rehab services, which in turn create downstream demand for pharmacological and supportive care treatments.

Additionally, clinical trials are gaining momentum, with more than 100 studies registered globally targeting muscle wasting and sarcopenia-related endpoints. Biopharma companies are forming strategic collaborations with academic centers and aging research institutes to accelerate drug discovery and expand the knowledge base. Regulatory bodies like the FDA and EMA have expressed willingness to consider surrogate endpoints such as gait speed and grip strength, which can shorten trial durations and facilitate faster approvals. Moreover, the availability of companion diagnostics and digital biomarkers is enhancing trial precision and post-market monitoring.

Growing public awareness, wearable technology adoption, and demand for aging-in-place solutions are further propelling this market. The convergence of biotechnology, diagnostics, and rehabilitation systems is laying the foundation for comprehensive sarcopenia management programs across care settings. As health systems evolve to meet the demands of an aging population, the sarcopenia treatment market is poised to see accelerated investment, clinical adoption, and commercial expansion worldwide.

Scope of the Report

The report analyzes the Sarcopenia Treatment market, presented in terms of market value (USD). The analysis covers the key segments and geographic regions outlined below:

• Segments: Treatment Type (Vitamin D & Calcium Supplements, Protein Supplements, Vitamin B12 Supplements, Other Treatment Types); Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Distribution Channel, Other Distribution Channels).
• Geographic Regions/Countries: World; United States; Canada; Japan; China; Europe (France; Germany; Italy; United Kingdom; Spain; Russia; and Rest of Europe); Asia-Pacific (Australia; India; South Korea; and Rest of Asia-Pacific); Latin America (Argentina; Brazil; Mexico; and Rest of Latin America); Middle East (Iran; Israel; Saudi Arabia; United Arab Emirates; and Rest of Middle East); and Africa.

Key Insights:

• Market Growth: Understand the significant growth trajectory of the Vitamin D & Calcium Supplements segment, which is expected to reach US$1.6 Billion by 2030 with a CAGR of a 4.4%. The Protein Supplements segment is also set to grow at 2.1% CAGR over the analysis period.
• Regional Analysis: Gain insights into the U.S. market, valued at $811.8 Million in 2024, and China, forecasted to grow at an impressive 6.2% CAGR to reach $718.5 Million by 2030. Discover growth trends in other key regions, including Japan, Canada, Germany, and the Asia-Pacific.

Why You Should Buy This Report:

• Detailed Market Analysis: Access a thorough analysis of the Global Sarcopenia Treatment Market, covering all major geographic regions and market segments.
• Competitive Insights: Get an overview of the competitive landscape, including the market presence of major players across different geographies.
• Future Trends and Drivers: Understand the key trends and drivers shaping the future of the Global Sarcopenia Treatment Market.
• Actionable Insights: Benefit from actionable insights that can help you identify new revenue opportunities and make strategic business decisions.

Key Questions Answered:

• How is the Global Sarcopenia Treatment Market expected to evolve by 2030?
• What are the main drivers and restraints affecting the market?
• Which market segments will grow the most over the forecast period?
• How will market shares for different regions and segments change by 2030?
• Who are the leading players in the market, and what are their prospects?

Report Features:

• Comprehensive Market Data: Independent analysis of annual sales and market forecasts in US$ Million from 2024 to 2030.
• In-Depth Regional Analysis: Detailed insights into key markets, including the U.S., China, Japan, Canada, Europe, Asia-Pacific, Latin America, Middle East, and Africa.
• Company Profiles: Coverage of players such as AbbVie Inc., Amgen Inc., Astellas Pharma Inc., Bayer AG, Biophytis SA and more.
• Complimentary Updates: Receive free report updates for one year to keep you informed of the latest market developments.

Some of the 34 companies featured in this Sarcopenia Treatment market report include:

• AbbVie Inc.
• Amgen Inc.
• Astellas Pharma Inc.
• Bayer AG
• Biophytis SA
• Bristol-Myers Squibb Company
• Eli Lilly and Company
• Endo International plc
• GlaxoSmithKline plc
• Hologic Inc.
• Merck & Co., Inc.
• MyoDyna AS
• Novartis AG
• Pfizer Inc.
• Radius Health Inc.
• Regeneron Pharmaceuticals
• Sanofi
• SARCO Biosystems Inc.
• TSI Group Ltd.
• Veru Inc.

This edition integrates the latest global trade and economic shifts into comprehensive market analysis. Key updates include:

• Tariff and Trade Impact: Insights into global tariff negotiations across 180+ countries, with analysis of supply chain turbulence, sourcing disruptions, and geographic realignment. Special focus on 2025 as a pivotal year for trade tensions, including updated perspectives on the Trump-era tariffs.
• Adjusted Forecasts and Analytics: Revised global and regional market forecasts through 2030, incorporating tariff effects, economic uncertainty, and structural changes in globalization. Includes historical analysis from 2015 to 2023.
• Strategic Market Dynamics: Evaluation of revised market prospects, regional outlooks, and key economic indicators such as population and urbanization trends.
• Innovation & Technology Trends: Latest developments in product and process innovation, emerging technologies, and key industry drivers shaping the competitive landscape.
• Competitive Intelligence: Updated global market share estimates for 2025 (E), competitive positioning of major players (Strong/Active/Niche/Trivial), and refined focus on leading global brands and core players.
• Expert Insight & Commentary: Strategic analysis from economists, trade experts, and domain specialists to contextualize market shifts and identify emerging opportunities.