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U.S. Small Molecule Drug Discovery Outsourcing Market Size, Share & Trends Analysis Report By Workflow (Target Identification & Screening, Target Validation & Functional Informatics), By Service, By Therapeutics Area, By End Use, And Segment Forecasts, 2025 - 2033- Product Image
U.S. Small Molecule Drug Discovery Outsourcing Market Size, Share & Trends Analysis Report By Workflow (Target Identification & Screening, Target Validation & Functional Informatics), By Service, By Therapeutics Area, By End Use, And Segment Forecasts, 2025 - 2033- Product Image
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U.S. Small Molecule Drug Discovery Outsourcing Market Size, Share & Trends Analysis Report By Workflow (Target Identification & Screening, Target Validation & Functional Informatics), By Service, By Therapeutics Area, By End Use, And Segment Forecasts, 2025 - 2033

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  • 120 Pages
  • July 2025
  • Region: United States
  • Grand View Research
  • ID: 6154484
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U.S. Small Molecule Drug Discovery Outsourcing Market Summary

The U.S. small molecule drug discovery outsourcing market size was estimated at USD 1.52 billion in 2024 and is projected to reach USD 3.47 billion by 2033, growing at a CAGR of 9.7% from 2025 to 2033. Increasing R&D expenses, rising focus on early-stage research activities, and growing biotech companies with limited in-house resources drive the market.

Besides, outsourcing has emerged as a strategic option for pharmaceutical and biotech companies aiming to accelerate the timelines, lower fixed overhead costs, and gain access to specialized expertise in areas such as medicinal chemistry, hit-to-lead optimization, ADME/PK studies, and IND-enabling activities.

Innovations like AI-driven compound design, CRISPR-based target validation, high-throughput screening, and 3D cell models transform discovery processes, enabling contract research organizations (CROs) to provide more efficient and predictive results. Furthermore, rising R&D costs, increased demand for drug development, and a shift towards virtual pharmaceutical models support the market. In addition, an increase in registered clinical studies, a higher approval rate for small molecule drugs, advancements in medical technology, a rise in diseases being studied, and the urgent need for new treatments are anticipated to drive the market.

U.S. Small Molecule Drug Discovery Outsourcing Market Report Segmentation

This report forecasts revenue growth at the country level and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, the analyst has segmented the U.S. small molecule drug discovery outsourcing market report based on workflow, service, therapeutics area, and end use:

Workflow Outlook (Revenue, USD Million, 2021 - 2033)

  • Target Identification & Screening
  • Target Validation & Functional Informatics
  • Lead Identification & Candidate Optimization
  • Preclinical Development
  • Others

Service Outlook (Revenue, USD Million, 2021 - 2033)

  • Chemistry Services
  • Biology Services

Therapeutics Area Outlook (Revenue, USD Million, 2021 - 2033)

  • Respiratory system
  • Pain and Anesthesia
  • Oncology
  • Ophthalmology
  • Hematology
  • Cardiovascular
  • Endocrine
  • Gastrointestinal
  • Immunomodulation
  • Anti-infective
  • Central Nervous System
  • Dermatology
  • Genitourinary System

End Use Outlook (Revenue, USD Million, 2021 - 2033)

  • Pharmaceutical & Biotechnology companies
  • Academic Institutes

Why should you buy this report?

  • Comprehensive Market Analysis: Gain detailed insights into the global market across major regions and segments.
  • Competitive Landscape: Explore the market presence of key players worldwide.
  • Future Trends: Discover the pivotal trends and drivers shaping the future of the global market.
  • Actionable Recommendations: Utilize insights to uncover new revenue streams and guide strategic business decisions.

This report addresses:

  • Market intelligence to enable effective decision-making
  • Market estimates and forecasts from 2018 to 2030
  • Growth opportunities and trend analyses
  • Segment and regional revenue forecasts for market assessment
  • Competition strategy and market share analysis
  • Product innovation listing for you to stay ahead of the curve
  • COVID-19's impact and how to sustain in these fast-evolving markets

This product will be delivered within 1-3 business days.

Table of Contents

Chapter 1. Research Methodology and Scope
1.1. Market Segmentation & Scope
1.2. Segment Definitions
1.2.1. Workflow
1.2.2. Service
1.2.3. Therapeutics Area
1.2.4. End Use
1.3. Research Methodology
1.4. Information Procurement
1.4.1. Purchased Database
1.4.2. Internal Database
1.4.3. Secondary Sources
1.4.4. Primary Research
1.5. Information Or Data Analysis
1.5.1. Data Analysis Models
1.6. Market Formulation & Validation
1.7. Model Details
1.7.1. Commodity flow analysis (Model 1)
1.7.2. Value chain-based analysis (Model 2)
1.7.3. Multivariate Analysis (Model 3)
1.8. List Of Secondary Sources
1.9. List Of Abbreviations
1.10. Objectives
Chapter 2. Executive Summary
2.1. Market Outlook
2.2. Segment Outlook
2.3. Competitive Insights
Chapter 3. U.S. Small Molecule Drug Discovery Outsourcing Market Variables, Trends & Scope
3.1. Market Lineage Outlook
3.1.1. Parent Market Outlook
3.1.2. Related/Ancillary Market Outlook
3.2. Market Dynamics
3.2.1. Market Driver Analysis
3.2.1.1. Increasing demand for outsourcing services in drug development
3.2.1.2. Technological advancements in drug discovery
3.2.1.3. Rising shortening time-to-market pressures
3.2.2. Market Restraint Analysis
3.2.2.1. Intellectual property (IP) and data security concerns
3.2.2.2. Limited standardization and reproducibility
3.3. Clinical Trials Volume Analysis, (2024)
3.3.1. Total Number Of Clinical Trials By Country
3.3.2. Total Number Of Clinical Trials, By Phase
3.3.3. Total Number Of Clinical Trials, By Study Design
3.3.4. Total Number Of Clinical Trials, By Key Therapeutic Area
3.4. Pricing Model Analysis
3.5. Technology Landscape
3.6. Market Analysis Tools
3.6.1. Porter’s Five Forces Analysis
3.6.2. PESTEL by SWOT Analysis
Chapter 4. U.S. Small Molecule Drug Discovery Outsourcing Market: Workflow Estimates & Trend Analysis
4.1. U.S. Small Molecule Drug Discovery Outsourcing Market, By Workflow: Segment Dashboard
4.2. U.S. Small Molecule Drug Discovery Outsourcing Market, By Workflow: Movement Analysis
4.3. U.S. Small Molecule Drug Discovery Outsourcing Market Estimates & Forecasts, By Workflow, 2021 - 2033 (USD Million)
4.4. Target Identification & Screening
4.4.1. Target Identification & Screening Market Estimates and Forecasts, 2021 - 2033 (USD Million)
4.5. Target Validation & Functional Informatics
4.5.1. Target Validation & Functional Informatics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
4.6. Lead Identification & Candidate Optimization
4.6.1. Lead Identification & Candidate Optimization Market Estimates and Forecasts, 2021 - 2033 (USD Million)
4.7. Preclinical Development
4.7.1. Preclinical Development Market Estimates and Forecasts, 2021 - 2033 (USD Million)
4.8. Others
4.8.1. Others Market Estimates and Forecasts, 2021 - 2033 (USD Million)
Chapter 5. U.S. Small Molecule Drug Discovery Outsourcing Market: Service Estimates & Trend Analysis
5.1. U.S. Small Molecule Drug Discovery Outsourcing Market, By Service: Segment Dashboard
5.2. U.S. Small Molecule Drug Discovery Outsourcing Market, By Service: Movement Analysis
5.3. U.S. Small Molecule Drug Discovery Outsourcing Market Estimates & Forecasts, By Service, 2021 - 2033 (USD Million)
5.4. Chemistry Services
5.4.1. Chemistry Services Market Estimates and Forecasts, 2021 - 2033 (USD Million)
5.5. Biology Services
5.5.1. Biology Services Market Estimates and Forecasts, 2021 - 2033 (USD Million)
Chapter 6. U.S. Small Molecule Drug Discovery Outsourcing Market: Therapeutics Area Estimates & Trend Analysis
6.1. U.S. Small Molecule Drug Discovery Outsourcing Market, By Therapeutics Area: Segment Dashboard
6.2. U.S. Small Molecule Drug Discovery Outsourcing Market, By Therapeutics Area: Movement Analysis
6.3. U.S. Small Molecule Drug Discovery Outsourcing Market Estimates & Forecasts, By Therapeutics Area, 2021 - 2033 (USD Million)
6.4. Respiratory system
6.4.1. Respiratory System Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.5. Pain and Anesthesia
6.5.1. Pain and Anesthesia Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.6. Oncology
6.6.1. Oncology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.7. Ophthalmology
6.7.1. Ophthalmology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.8. Hematology
6.8.1. Hematology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.9. Cardiovascular
6.9.1. Cardiovascular Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.10. Endocrine
6.10.1. Endocrine Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.11. Gastrointestinal
6.11.1. Gastrointestinal Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.12. Immunomodulation
6.12.1. Immunomodulation Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.13. Anti-infective
6.13.1. Anti-infective Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.14. Central Nervous System
6.14.1. Central Nervous System Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.15. Dermatology
6.15.1. Dermatology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.16. Genitourinary System
6.16.1. Genitourinary System Market Estimates and Forecasts, 2021 - 2033 (USD Million)
Chapter 7. U.S. Small Molecule Drug Discovery Outsourcing Market: End Use Estimates & Trend Analysis
7.1. U.S. Small Molecule Drug Discovery Outsourcing Market, By End Use: Segment Dashboard
7.2. U.S. Small Molecule Drug Discovery Outsourcing Market, By End Use: Movement Analysis
7.3. U.S. Small Molecule Drug Discovery Outsourcing Market Estimates & Forecasts, By End Use, 2021 - 2033 (USD Million)
7.4. Pharmaceutical & Biotechnology companies
7.4.1. Pharmaceutical & Biotechnology companies Market Estimates and Forecasts, 2021 - 2033 (USD Million)
7.5. Academic Institutes
7.5.1. Academic Institutes Market Estimates and Forecasts, 2021 - 2033 (USD Million)
Chapter 8. Competitive Landscape
8.1. Market Participant Categorization
8.1.1. Market Leaders
8.1.2. Emerging Players
8.2. Company Market Share/Assessment Analysis, 2024
8.3. Company Profiles
8.3.1. Charles River Laboratories
8.3.1.1. Company Overview
8.3.1.2. Financial Performance
8.3.1.3. Service Benchmarking
8.3.1.4. Strategic Initiatives
8.3.2. Laboratory Corporation of America Holdings (Covance)
8.3.2.1. Company Overview
8.3.2.2. Financial Performance
8.3.2.3. Service Benchmarking
8.3.2.4. Strategic Initiatives
8.3.3. Albany Molecular Research (Curia)
8.3.3.1. Company Overview
8.3.3.2. Financial Performance
8.3.3.3. Service Benchmarking
8.3.3.4. Strategic Initiatives
8.3.4. Merck & Co., Inc.
8.3.4.1. Company Overview
8.3.4.2. Financial Performance
8.3.4.3. Service Benchmarking
8.3.4.4. Strategic Initiatives
8.3.5. QIAGEN
8.3.5.1. Company Overview
8.3.5.2. Financial Performance
8.3.5.3. Service Benchmarking
8.3.5.4. Strategic Initiatives
8.3.6. Eurofins
8.3.6.1. Company Overview
8.3.6.2. Financial Performance
8.3.6.3. Service Benchmarking
8.3.6.4. Strategic Initiatives
8.3.7. Evotec
8.3.7.1. Company Overview
8.3.7.2. Financial Performance
8.3.7.3. Service Benchmarking
8.3.7.4. Strategic Initiatives
8.3.8. GenScript Biotech
8.3.8.1. Company Overview
8.3.8.2. Financial Performance
8.3.8.3. Service Benchmarking
8.3.8.4. Strategic Initiatives
8.3.9. Pharmaron
8.3.9.1. Company Overview
8.3.9.2. Financial Performance
8.3.9.3. Service Benchmarking
8.3.9.4. Strategic Initiatives
8.3.10. Syngene International
8.3.10.1. Company Overview
8.3.10.2. Financial Performance
8.3.10.3. Service Benchmarking
8.3.10.4. Strategic Initiatives
8.3.11. Dalton Pharma Services
8.3.11.1. Company Overview
8.3.11.2. Financial Performance
8.3.11.3. Service Benchmarking
8.3.11.4. Strategic Initiatives
8.3.12. Oncodesign
8.3.12.1. Company Overview
8.3.12.2. Financial Performance
8.3.12.3. Service Benchmarking
8.3.12.4. Strategic Initiatives
8.3.13. Jubilant Biosys
8.3.13.1. Company Overview
8.3.13.2. Financial Performance
8.3.13.3. Service Benchmarking
8.3.13.4. Strategic Initiatives
8.3.14. Domainex
8.3.14.1. Company Overview
8.3.14.2. Financial Performance
8.3.14.3. Service Benchmarking
8.3.14.4. Strategic Initiatives
8.3.15. Dr. Reddy Laboratories Ltd.
8.3.15.1. Company Overview
8.3.15.2. Financial Performance
8.3.15.3. Service Benchmarking
8.3.15.4. Strategic Initiatives
8.3.16. Pharmaron Beijing Co., Ltd.
8.3.16.1. Company Overview
8.3.16.2. Financial Performance
8.3.16.3. Service Benchmarking
8.3.16.4. Strategic Initiatives
8.3.17. TCG Lifesciences Pvt Ltd.
8.3.17.1. Company Overview
8.3.17.2. Financial Performance
8.3.17.3. Service Benchmarking
8.3.17.4. Strategic Initiatives
Chapter 9. Key Recommendations
List of Tables
Table 1 List of Tables
Table 2 List of Secondary Sources
Table 3 List of Abbreviations
Table 4 U.S. Small Molecule Drug Discovery Outsourcing Market Estimates and Forecasts, by Workflow, 2021 - 2033 (USD Million)
Table 5 U.S. Small Molecule Drug Discovery Outsourcing Market Estimates and Forecasts, by Service, 2021 - 2033 (USD Million)
Table 6 U.S. Small Molecule Drug Discovery Outsourcing Market Estimates and Forecasts, by Therapeutics Area, 2021 - 2033 (USD Million)
Table 7 U.S. Small Molecule Drug Discovery Outsourcing Market Estimates and Forecasts, by End Use, 2021 - 2033 (USD Million)
List of Figures
Fig. 1 Market research process
Fig. 2 Information procurement
Fig. 3 Primary research pattern
Fig. 4 Market research approaches
Fig. 5 Market formulation & validation
Fig. 6 Commodity flow analysis
Fig. 7 Value-chain-based sizing & forecasting
Fig. 8 QFD model sizing & forecasting
Fig. 9 Bottom-up approach
Fig. 10 Market snapshot
Fig. 11 Segment snapshot 1
Fig. 12 Segment snapshot 2
Fig. 13 Competitive landscape snapshot
Fig. 14 Parent market outlook, 2024 (USD Billion)
Fig. 15 Ancillary market outlook, 2024 (USD Billion)
Fig. 16 U.S. small molecule drug discovery outsourcing market dynamics
Fig. 17 Porter’s five forces analysis
Fig. 18 PESTEL analysis
Fig. 19 U.S. Small molecule drug discovery outsourcing market: workflow outlook and key takeaways
Fig. 20 U.S. small molecule drug discovery outsourcing market: workflow movement analysis
Fig. 21 Target identification & screening market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 22 Target validation & functional informatics market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 23 Lead identification & candidate optimization market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 24 Preclinical development market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 25 Other market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 26 U.S. small molecule drug discovery outsourcing market: Service outlook and key takeaways
Fig. 27 U.S. small molecule drug discovery outsourcing market: Service movement analysis
Fig. 28 Chemistry services market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 29 Biology services market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 30 U.S. small molecule drug discovery outsourcing market: therapeutics area outlook and key takeaways
Fig. 31 U.S. small molecule drug discovery outsourcing market: therapeutics area movement analysis
Fig. 32 Respiratory system market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 33 Pain and anesthesia market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 34 Oncology market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 35 Ophthalmology market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 36 Hematology market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 37 Cardiovascular market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 38 Endocrine market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 39 Gastrointestinal market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 40 Immunomodulation market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 41 Anti-infective market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 42 Central nervous system market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 43 Dermatology market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 44 Genitourinary system market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 45 U.S. small molecule drug discovery outsourcing market: End use outlook and key takeaways
Fig. 46 U.S. small molecule drug discovery outsourcing market: End use movement analysis
Fig. 47 Pharmaceutical & biotechnology companies market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 48 Academic institutes market estimates and forecasts, 2021 - 2033 (USD Million)
Fig. 49 Key company categorization
Fig. 50 Service heat map analysis
Fig. 51 Strategic framework

Companies Mentioned

  • Charles River Laboratories
  • Laboratory Corporation of America Holdings (Covance)
  • Albany Molecular Research (Curia)
  • Merck & Co., Inc.
  • QIAGEN
  • Eurofins
  • Evotec
  • GenScript Biotech
  • Pharmaron
  • Syngene International
  • Dalton Pharma Services
  • Oncodesign
  • Jubilant Biosys
  • Domainex
  • Dr. Reddy Laboratories Ltd.
  • Pharmaron Beijing Co., Ltd.
  • TCG Lifesciences Pvt Ltd.

Table Information

Report AttributeDetails
No. of Pages120
PublishedJuly 2025
Forecast Period2024 - 2033
Estimated Market Value ( USD ) in 2024 $ 1.52 Billion
Forecasted Market Value ( USD ) by 2033 $ 3.47 Billion
Compound Annual Growth Rate9.7%
Regions CoveredUnited States
No. of Companies Mentioned17

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