The global companion animal osteoarthritis market size was estimated at USD 2.29 billion in 2024 and is projected to reach USD 13.27 billion by 2033, growing at a CAGR of 23.5% from 2025 to 2033. Key factors expected to drive the market include the rising prevalence of osteoarthritis, increasing R&D initiative, emerging novel treatments, increasing awareness campaigns, and advancing diagnostic techniques increasing adoption of osteoarthritis (OA) treatment.
The rising prevalence of osteoarthritis (OA) in companion animals-particularly dogs, cats, and horses-is significantly driving the global companion animal osteoarthritis market. In canines alone, estimates suggest that approximately 20% of dogs over one year of age show clinical signs of OA, and this prevalence can escalate to as high as 80% in older dogs, according to both clinical observations and radiographic studies. Similar trends are observed in felines, where OA is often underdiagnosed but increasingly recognized in aging cat populations, with some studies indicating radiographic signs in up to 90% of cats over 12 years old. Equine OA also remains a leading cause of reduced performance and early retirement, especially in sport and racehorses.
Several factors are contributing to this increase in OA prevalence, including extended pet lifespans due to advances in nutrition and veterinary care, rising rates of obesity (a major OA risk factor), and improved awareness and diagnostic capabilities among veterinarians and pet owners. These trends are expanding the demand for early diagnosis, chronic disease management, and pain relief solutions.
This growing burden has catalyzed significant investment and innovation in OA therapeutics, including the development of novel biologics, regenerative therapies (e.g., stem cells and PRP), monoclonal antibodies (such as Zoetis’ Librela and Solensia), and other multimodal pain management approaches. Pharmaceutical and biotech companies are actively developing long-acting, targeted therapies that offer better compliance and improved quality of life for pets, particularly as pet owners increasingly seek premium and preventative care. In parallel, the surge in veterinary visits and emphasis on mobility monitoring and wellness programs is reinforcing a robust market for diagnostics, supplements, joint-support diets, and rehabilitation services.
Altogether, these epidemiological and behavioral factors are not only expanding the companion animal OA patient pool but are also transforming the disease into a cornerstone segment of the global animal health industry-creating long-term growth opportunities across therapeutics, diagnostics, and supportive care solutions.
Despite strong market performance and widespread adoption of OA-targeting monoclonal antibodies like Librela, the recent public controversy-including calls for outright bans and new data suggesting a nine fold increase in musculoskeletal adverse events-poses a reputational and regulatory challenge. Heightened scrutiny from regulators like the FDA and EMA may result in tougher post market surveillance, label revisions, or prescribing restrictions. In the short term, veterinarians and pet owners might pivot toward more conservative options, such as established NSAIDs or supplements, potentially slowing growth in the biologics segment. However, transparent safety studies, improved pharmacovigilance, and clear risk-benefit guidelines could restore confidence and ultimately solidify the position of mAb therapies as a premium OA treatment-assuming manufacturers respond proactively
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The rising prevalence of osteoarthritis (OA) in companion animals-particularly dogs, cats, and horses-is significantly driving the global companion animal osteoarthritis market. In canines alone, estimates suggest that approximately 20% of dogs over one year of age show clinical signs of OA, and this prevalence can escalate to as high as 80% in older dogs, according to both clinical observations and radiographic studies. Similar trends are observed in felines, where OA is often underdiagnosed but increasingly recognized in aging cat populations, with some studies indicating radiographic signs in up to 90% of cats over 12 years old. Equine OA also remains a leading cause of reduced performance and early retirement, especially in sport and racehorses.
Several factors are contributing to this increase in OA prevalence, including extended pet lifespans due to advances in nutrition and veterinary care, rising rates of obesity (a major OA risk factor), and improved awareness and diagnostic capabilities among veterinarians and pet owners. These trends are expanding the demand for early diagnosis, chronic disease management, and pain relief solutions.
This growing burden has catalyzed significant investment and innovation in OA therapeutics, including the development of novel biologics, regenerative therapies (e.g., stem cells and PRP), monoclonal antibodies (such as Zoetis’ Librela and Solensia), and other multimodal pain management approaches. Pharmaceutical and biotech companies are actively developing long-acting, targeted therapies that offer better compliance and improved quality of life for pets, particularly as pet owners increasingly seek premium and preventative care. In parallel, the surge in veterinary visits and emphasis on mobility monitoring and wellness programs is reinforcing a robust market for diagnostics, supplements, joint-support diets, and rehabilitation services.
Altogether, these epidemiological and behavioral factors are not only expanding the companion animal OA patient pool but are also transforming the disease into a cornerstone segment of the global animal health industry-creating long-term growth opportunities across therapeutics, diagnostics, and supportive care solutions.
Despite strong market performance and widespread adoption of OA-targeting monoclonal antibodies like Librela, the recent public controversy-including calls for outright bans and new data suggesting a nine fold increase in musculoskeletal adverse events-poses a reputational and regulatory challenge. Heightened scrutiny from regulators like the FDA and EMA may result in tougher post market surveillance, label revisions, or prescribing restrictions. In the short term, veterinarians and pet owners might pivot toward more conservative options, such as established NSAIDs or supplements, potentially slowing growth in the biologics segment. However, transparent safety studies, improved pharmacovigilance, and clear risk-benefit guidelines could restore confidence and ultimately solidify the position of mAb therapies as a premium OA treatment-assuming manufacturers respond proactively
Global Companion Animal Osteoarthritis Market Report Segmentation
This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, the analyst has segmented the companion animal osteoarthritis market report based on product, animal, route of administration, end use, and region:Product Outlook (Revenue, USD Million, 2021 - 2033)
- Biologics
- Stem Cells
- Platelet-Rich Plasma (PRP)
- Monoclonal Antibodies (mAb)
- Other Biologics
- Viscosupplements
- Pharmaceuticals
- Steroids
- NSAIDS
- Others
- Nutritional Supplements
Animal Outlook (Revenue, USD Million, 2021 - 2033)
- Canine
- Equine
- Feline
Route of Administration Outlook (Revenue, USD Million, 2021 - 2033)
- Oral
- Injectable
- Intra-muscular
- Intra-articular
- Other Injectable
- Others
End Use Outlook (Revenue, USD Million, 2021 - 2033)
- Veterinary Hospitals/Clinics
- E-commerce
- Others
Regional Outlook (Revenue, USD Million, 2021 - 2033)
- North America
- U.S.
- Canada
- Mexico
- Europe
- UK
- Germany
- France
- Italy
- Spain
- Denmark
- Sweden
- Norway
- Asia Pacific
- Japan
- India
- China
- South Korea
- Australia
- Thailand
- Latin America
- Brazil
- Argentina
- Middle East and Africa (MEA)
- South Africa
- Saudi Arabia
- UAE
- Kuwait
Why should you buy this report?
- Comprehensive Market Analysis: Gain detailed insights into the global market across major regions and segments.
- Competitive Landscape: Explore the market presence of key players worldwide.
- Future Trends: Discover the pivotal trends and drivers shaping the future of the global market.
- Actionable Recommendations: Utilize insights to uncover new revenue streams and guide strategic business decisions.
This report addresses:
- Market intelligence to enable effective decision-making
- Market estimates and forecasts from 2018 to 2030
- Growth opportunities and trend analyses
- Segment and regional revenue forecasts for market assessment
- Competition strategy and market share analysis
- Product innovation listing for you to stay ahead of the curve
- COVID-19's impact and how to sustain in these fast-evolving markets
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Table of Contents
Chapter 1. Methodology and Scope
Chapter 2. Executive Summary
Chapter 3. Companion Animal Osteoarthritis Market Variable Trends & Scope
Chapter 4. Companion Animal Osteoarthritis Market: Product Estimates & Trend Analysis
Chapter 5. Companion Animal Osteoarthritis Market: Animal Estimates & Trend Analysis
Chapter 6. Companion Animal Osteoarthritis Market: By Route of Administration Estimates & Trend Analysis
Chapter 7. Companion Animal Osteoarthritis Market: By End Use Estimates & Trend Analysis
Chapter 8. Companion Animal Osteoarthritis Market: Regional Estimates & Trend Analysis
Chapter 9. Competitive Landscape
List of Tables
List of Figures
Companies Mentioned
- Zoetis Inc.
- Boehringer Ingelheim
- Elanco Animal Health
- American Regent, Inc.
- Merck Animal Health (Merck & Co. Inc)
- Vetoquinol S.A.
- Ceva Sante Animale
- Virbac
- Biogenesis Bago
- Ardent Animal Health, LLC
- PetVivo Holdings, Inc. (Spryng)
- VetStem, Inc.
- Enso Discoveries
- Contura Vet US
- T-Cyte Therapeutics
- MEDREGO LLC