The U.S. healthcare information systems market size was estimated at USD 238.45 billion in 2024 and is projected to reach USD 678.39 billion by 2033, growing at a CAGR of 12.40% from 2025 to 2033. The increasing prevalence of chronic diseases in the country is driving the adoption of remote patient monitoring. This growing trend is anticipated to enhance the demand for IT solutions within the healthcare industry in the U.S. In addition, the industry is expected to experience growth driven by several advantages, including operational cost reductions, a decrease in medical errors, and enhanced patient outcomes. Moreover, supportive government initiatives aimed at developing healthcare infrastructure and integrating IT solutions into existing facilities are anticipated to further stimulate industry expansion during the forecast period.
The push for interoperability is a key driver in the U.S. healthcare information systems market. Providers, payers, and patients require seamless access to data across different systems to support care coordination. Regulations under the 21st Century Cures Act mandate the elimination of information blocking, further accelerating the need for interoperable platforms. Systems that enable data exchange between hospitals, diagnostic centers, ambulatory care, and insurers are becoming essential. Such regulatory and operational demand is driving upgrades to existing healthcare IT infrastructures. For instance, in August 2025, Epic unveiled significant artificial intelligence (AI) features integrated into its electronic health record (EHR) platform, including AI-assisted charting to streamline documentation, Microsoft’s Cosmos AI for enhanced risk prediction, and revenue cycle management (RCM) improvements. These advancements aim to boost clinical efficiency, optimize patient care, and improve financial workflows for healthcare providers.
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The push for interoperability is a key driver in the U.S. healthcare information systems market. Providers, payers, and patients require seamless access to data across different systems to support care coordination. Regulations under the 21st Century Cures Act mandate the elimination of information blocking, further accelerating the need for interoperable platforms. Systems that enable data exchange between hospitals, diagnostic centers, ambulatory care, and insurers are becoming essential. Such regulatory and operational demand is driving upgrades to existing healthcare IT infrastructures. For instance, in August 2025, Epic unveiled significant artificial intelligence (AI) features integrated into its electronic health record (EHR) platform, including AI-assisted charting to streamline documentation, Microsoft’s Cosmos AI for enhanced risk prediction, and revenue cycle management (RCM) improvements. These advancements aim to boost clinical efficiency, optimize patient care, and improve financial workflows for healthcare providers.
U.S. Healthcare Information Systems Market Report Segmentation
This report forecasts revenue growth at country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. The analyst has segmented U.S. healthcare information systems market report based on application, deployment mode, component, and end use.Application Outlook (Revenue, USD Million, 2021-2033)
- Hospital Information System
- Electronic Health Record
- Electronic Medical Record
- Real-time Healthcare
- Patient Engagement Solution
- Population Health Management
- Pharmacy Automation Systems
- Medication Dispensing System
- Packaging & Labeling System
- Storage & Retrieval System
- Automated Medication Compounding System
- Tabletop Tablet Counters
- Laboratory Informatics
- Revenue Cycle Management
- Medical Imaging Information System
- Radiology Information Systems
- Monitoring Analysis Software
- Picture Archiving and Communication Systems
Deployment Outlook (Revenue, USD Million, 2021-2033)
- Web-based
- On-premises
- Cloud-based
Component Outlook (Revenue, USD Million, 2021-2033)
- Hardware
- Software & Systems
- Services
End Use Outlook (Revenue, USD Million, 2021-2033)
- Hospitals & Ambulatory Services
- Diagnostic Centers
- Academic and Research Institutes
Why should you buy this report?
- Comprehensive Market Analysis: Gain detailed insights into the industry across major regions and segments.
- Competitive Landscape: Explore the market presence of key players.
- Future Trends: Discover the pivotal trends and drivers shaping the future of the market.
- Actionable Recommendations: Utilize insights to uncover new revenue streams and guide strategic business decisions.
This report addresses:
- Market intelligence to enable effective decision-making
- Market estimates and forecasts from 2018 to 2030
- Growth opportunities and trend analyses
- Segmental and regional revenue forecasts for market assessment
- Competition strategy and market share analysis
- Product innovation listings for you to stay ahead of the curve
- COVID-19's impact and how to sustain in these fast-evolving markets
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Table of Contents
Chapter 1. Methodology and Scope
Chapter 2. Executive Summary
Chapter 3. U.S. Healthcare Information Systems Market Variables, Trends & Scope
Chapter 4. U.S. Healthcare Information Systems Market: Device Type Estimates & Trend Analysis
Chapter 5. U.S. Healthcare Information Systems Market: Deployment Estimates & Trend Analysis
Chapter 6. U.S. Healthcare Information Systems Market: Component Estimates & Trend Analysis
Chapter 7. U.S. Healthcare Information Systems Market: End Use Estimates & Trend Analysis
Chapter 8. Competitive Landscape
List of Tables
List of Figures
Companies Mentioned
The major companies profiled in this U.S. Healthcare Information System market report include:- Athenahealth Inc.
- Change Healthcare Inc.
- GE Healthcare
- IBM
- Oracle Corporation
- Dell Technologies Inc.
- Philips Healthcare
- Optum
- Infor
- Epic Systems Corporation
- Veradigm LLC.
- Conduent Inc.
- Cognizant Technology Solutions Corporation
- eClinicalWorks LLC
Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 100 |
| Published | August 2025 |
| Forecast Period | 2024 - 2033 |
| Estimated Market Value ( USD | $ 238.45 Billion |
| Forecasted Market Value ( USD | $ 678.39 Billion |
| Compound Annual Growth Rate | 12.4% |
| Regions Covered | United States |
| No. of Companies Mentioned | 15 |
