Oral Clinical Nutrition Supplement Market Report 2025

The oral clinical nutrition supplement market size has grown strongly in recent years. It will grow from $12.35 billion in 2024 to $13.22 billion in 2025 at a compound annual growth rate (CAGR) of 7%. The growth during the historic period can be attributed to the rising awareness of nutritional benefits, the increasing prevalence of chronic diseases, the expanding elderly population, the growing incidence of malnutrition, and the heightened demand for condition-specific nutrition.

The oral clinical nutrition supplement market size is expected to see strong growth in the next few years. It will grow to $17.1 billion in 2029 at a compound annual growth rate (CAGR) of 6.7%. The growth in the forecast period can be attributed to the increasing prevalence of cancer, the expanding geriatric population, rising healthcare awareness, growing demand for personalized nutrition, and greater awareness of supplements in developing regions. Key trends expected during this period include advancements in personalized nutrition, the integration of functional ingredients, technological innovations in formulation, progress in product delivery formats, and developments in sustainable packaging.

The rising focus on preventive healthcare is expected to drive the growth of the oral clinical nutrition supplement market in the coming years. Preventive healthcare refers to medical practices and lifestyle approaches aimed at reducing the risk of illness, enabling early detection, and supporting long-term wellness. This trend is growing as awareness of chronic diseases increases, encouraging people to take proactive measures to avoid complications and lower healthcare costs. Oral clinical nutrition supplements play a key role in preventive healthcare by providing essential nutrients that strengthen immunity, help maintain a healthy weight, reduce malnutrition risks, and support the management of chronic conditions, thereby improving overall well-being. For example, in March 2025, Eurostat, a Luxembourg-based government agency, reported that European countries spent \$103.03 billion (€90.4 billion) on preventive healthcare in 2022, equivalent to 0.57% of GDP, highlighting a significant investment in prevention. Therefore, the emphasis on preventive healthcare is boosting demand for oral clinical nutrition supplements.

Leading companies in the oral clinical nutrition supplement market are introducing advanced solutions such as clinical over-the-counter eye supplements to support eye health and meet the rising demand for specialized nutrition. These supplements are non-prescription products that provide vitamins, minerals, and antioxidants to protect visual function, reduce eye strain, and slow age-related degeneration. For instance, in June 2024, Bausch + Lomb Corporation, a Canada-based eye health company, launched Blink Nutritears, a novel supplement designed to promote healthy tear production and enhance ocular health through a proprietary nutrient blend. The product delivers targeted bioactive ingredients with improved bioavailability and clinically validated efficacy, helping maintain tear film stability, improve hydration, and support long-term eye comfort and protection.

In November 2024, Paine Schwartz Partners, a US-based investment firm specializing in sustainable food chains, acquired Promix LLC for an undisclosed amount. The acquisition aims to expand Paine Schwartz’s presence in the nutrition and wellness sector by adding performance-focused, high-quality nutritional products to its portfolio. Promix LLC is a US-based natural nutrition supplement company that manufactures oral clinical nutrition supplements.

Major players in the oral clinical nutrition supplement market are Pfizer Inc., Abbott Laboratories, Danone S.A., Medline Industries LP, Otsuka Pharmaceutical Co. Ltd., Ajinomoto Cambrooke Inc., Fresenius Kabi Aktiengesellschaft, Nestlé Health Science S.A, Metagenics Inc., Blackmores Limited, Wockhardt Ltd., B. Braun SE, Kate Farms Inc., Lipa Pharmaceuticals Limited, Cytoplan Ltd., Pristine Organics Pvt. Ltd., Medtrition Inc., Medifood International SA, Victus Inc., Nualtra Limited.

North America was the largest region in the oral clinical nutrition supplement market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in oral clinical nutrition supplement market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa. The countries covered in the oral clinical nutrition supplement market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report’s Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sudden escalation of U.S. tariffs and the consequent trade frictions in spring 2025 are severely impacting the pharmaceutical companies contend with tariffs on APIs, glass vials, and lab equipment inputs with few alternative sources. Generic drug makers, operating on razor-thin margins, are especially vulnerable, with some reducing production of low-profit medicines. Biotech firms face delays in clinical trials due to tariff-related shortages of specialized reagents. In response, the industry is expanding API production in India and Europe, increasing inventory stockpiles, and pushing for trade exemptions for essential medicines.

Oral clinical nutrition supplements are medically formulated products consumed orally to provide essential nutrients for individuals with dietary deficiencies or specific medical conditions. They help support recovery, manage malnutrition, and enhance overall nutritional status when regular dietary intake is inadequate.

The main categories of oral clinical nutrition supplements include liquid supplements, powder supplements, ready-to-drink supplements, and gel supplements. Liquid supplements are nutrient-dense fluids designed to deliver essential vitamins, minerals, and other dietary components for health maintenance and nourishment. These supplements are prescribed for a wide range of conditions, including inflammatory bowel disease, gastrointestinal and neurological disorders, respiratory diseases, diabetes, dysphagia, renal and hepatic disorders, oncology-related nutrition needs, and more. They are distributed through various channels such as hospital pharmacies, retail pharmacies, online platforms, and others. Oral clinical nutrition supplements are applied in settings like hospitals, home care, and long-term care facilities, and are used by diverse end users, including adults, children, the elderly, individuals with chronic illnesses, and athletes.

The oral clinical nutrition supplement market research report is one of a series of new reports that provides oral clinical nutrition supplement market statistics, including oral clinical nutrition supplement industry global market size, regional shares, competitors with an oral clinical nutrition supplement market share, detailed oral clinical nutrition supplement market segments, market trends and opportunities, and any further data you may need to thrive in the oral clinical nutrition supplement industry. This oral clinical nutrition supplement market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The oral clinical nutrition supplement market consists of sales of high-protein formula supplements, high-calorie (energy-dense) formula supplements, disease-specific formula supplements, and peptide-based (semi-elemental) formula supplements. Values in this market are ‘factory gate’ values; that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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