Next-Generation Mass Spectrometer Market Report 2025

The next-generation mass spectrometer market size has grown rapidly in recent years. It will grow from $3.26 billion in 2024 to $3.6 billion in 2025 at a compound annual growth rate (CAGR) of 10.2%. The growth in the historic period can be ascribed to the increasing adoption of next-generation mass spectrometry in pharmaceutical research, a rising demand for food safety testing, expanding applications in environmental monitoring, growth in academic proteomics studies, and increased government funding for clinical diagnostics.

The next-generation mass spectrometer market size is expected to see strong growth in the next few years. It will grow to $5.24 billion in 2029 at a compound annual growth rate (CAGR) of 9.9%. The growth in the forecast period can be attributed to the rising demand for personalized medicine, expanding applications in biotechnology and life sciences, increasing prevalence of chronic diseases requiring molecular diagnostics, growth in forensic and toxicology testing, and heightened regulatory requirements for contaminant analysis. Key trends during the forecast period include the development of miniaturized and portable instruments, advancements in software and AI-driven data analysis, progress in proteomics and metabolomics research, and increased automation and integration in high-throughput analytical workflows.

The growing emphasis on personalized medicine is driving the growth of the next-generation mass spectrometer market. Personalized medicine tailors treatments to an individual’s unique genetic, environmental, and lifestyle factors, aiming to improve patient outcomes, reduce side effects, and optimize healthcare efficiency. Next-generation mass spectrometers support this approach by providing precise and comprehensive molecular analysis, enabling identification of individual biomarkers, monitoring therapeutic responses, and guiding tailored treatment plans. For example, according to the Personalized Medicine Coalition, in 2023, the FDA approved 16 new personalized medicines for rare disease patients, up from six in 2022. This rising focus on personalized medicine is therefore propelling demand for advanced mass spectrometry solutions.

Companies in this market are focusing on high-performance mass spectrometry technologies to analyze complex biological samples with exceptional precision and speed. These innovations facilitate biomarker discovery, early disease detection, and development of personalized therapies. For instance, in June 2023, Thermo Fisher Scientific launched the Orbitrap Astral mass spectrometer, featuring ultra-fast scan speeds, high sensitivity, deep proteome coverage, improved ion transmission, and up to four times higher throughput. This advancement allows researchers to detect low-abundance proteins, accelerating large-scale proteomic analysis and the development of targeted treatments.

In July 2024, Thermo Fisher Scientific acquired Olink Holdings AB for $3.1 billion. This acquisition integrates Olink’s next-generation proteomics solutions into Thermo Fisher’s mass spectrometry portfolio, enhancing capabilities in protein analysis, accelerating scientific discovery, and supporting precision medicine initiatives. Olink Holdings AB, based in Sweden, specializes in advanced proteomics solutions for next-generation mass spectrometers.

Major players in the next-generation mass spectrometer market are Hitachi Ltd., F. Hoffmann-La Roche Ltd, Thermo Fisher Scientific Inc., Danaher Corporation, Agilent Technologies Inc., PerkinElmer Inc., Shimadzu Corporation, Waters Corporation, Bruker Corporation, HORIBA Ltd., JEOL Ltd., Rigaku Corporation, LECO Corporation, Hiden Analytical Ltd., Scion Instruments Ltd., MOBILion Systems Inc., Jiangsu Skyray Instrument Co. Ltd., Spacetek Technology Inc., and Hexsor Scientific Ltd.

North America was the largest region in the next-generation mass spectrometer market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in next-generation mass spectrometer market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa. The countries covered in the next-generation mass spectrometer market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report’s Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The fast surge in U.S. tariffs and the trade tensions that followed in spring 2025 are heavily affecting the medical equipment sector, particularly for imported imaging machine components, surgical-grade stainless steel, and plastic disposables. Hospitals and clinics resist price hikes, pressuring manufacturers’ margins. Regulatory hurdles compound the problem, as tariff-related supplier changes often require re-certification of devices, delaying time-to-market. Companies are mitigating risks by dual-sourcing critical parts, expanding domestic production of commoditized items, and accelerating R&D in cost-efficient materials.

Next-generation mass spectrometers are advanced analytical instruments engineered to deliver ultra-high sensitivity, resolution, and speed for detecting and quantifying molecules across diverse applications, including proteomics, metabolomics, drug discovery, and environmental analysis. These instruments often incorporate cutting-edge technologies such as artificial intelligence, novel ion optics, and real-time data processing to enhance performance, minimize sample requirements, and provide more precise and comprehensive molecular insights.

The primary types of next-generation mass spectrometers include Fourier transform mass spectrometry, linear ion trap mass spectrometry, and others. Fourier transform mass spectrometry uses a mathematical approach to convert a time-domain signal into its frequency-domain representation, revealing how the signal’s energy is distributed across different frequencies. Key applications span pharmaceuticals, biotechnology, clinical diagnostics, environmental analysis, food and beverage testing, forensic science, and more. End users include research laboratories, academic institutions, pharmaceutical companies, biotechnology firms, clinical laboratories, and government agencies.

The next-generation mass spectrometer market research report is one of a series of new reports that provides next-generation mass spectrometer market statistics, including the next-generation mass spectrometer industry global market size, regional shares, competitors with the next-generation mass spectrometer market share, detailed next-generation mass spectrometer market segments, market trends, and opportunities, and any further data you may need to thrive in the next-generation mass spectrometer industry. This next-generation mass spectrometer market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The next-generation mass spectrometer consists of sales of electrospray ionization, atmospheric pressure chemical ionization, trapped ion mobility spectrometry, faraday cups, and photodiode arrays. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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