The U.S. healthcare API market size was estimated at USD 303.3 Million in 2025 and is projected to reach USD 413.7 million by 2033, growing at a CAGR of 4.0% from 2025 to 2033. Healthcare APIs allow the integration of electronic health records (EHRs), diagnostic tools, and patient management systems.
This can provide simplicity and accessibility to healthcare data, which is expected to drive market growth. Healthcare providers are accelerating their digital transformation initiatives, creating strong demand for the U.S. healthcare API market. As hospitals and outpatient facilities modernize infrastructure to support electronic health records (EHRs), telehealth, remote patient monitoring, and AI-powered diagnostics, APIs serve as the essential backbone enabling system integration and real-time data exchange. From enhancing patient portals to automating clinical workflows and improving care coordination, APIs help providers bridge siloed systems. Initiatives such as cloud migration, interoperability mandates, and digital front-door strategies further amplify this demand. Providers are increasingly seeking standards-based, scalable APIs to integrate third-party apps, ensure compliance, and deliver connected, patient-centered care.
Advanced healthcare IT infrastructure, growing strategies and initiatives by key market players, investments supporting telemedicine's growth, and a growing emphasis on data interoperability. For instance, in March 2025, Alphabet Inc. launched global FHIR-compliant Medical Records APIs in Health Connect, enabling apps to securely read and write clinical data such as allergies, medications, immunizations, and lab results, now supporting over 50 health data types on-device. Hospitals, clinics, insurers, and digital health platforms across the country increasingly rely on APIs to streamline data exchange, enhance care coordination, and improve patient engagement through integrated digital services. Some of the APIs used by healthcare providers in the U.S. include:
Moreover, the shift toward patient-centric healthcare and government initiatives such as the 21st Century Cures Act in the U.S., which requires open API access to patient data, also adds to the key factors driving the market growth. APIs empower patients by enabling them to access and manage their health data through mobile apps and wearable devices. This increasing emphasis on using APIs likely to drive the demand for APIs and market growth.
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This can provide simplicity and accessibility to healthcare data, which is expected to drive market growth. Healthcare providers are accelerating their digital transformation initiatives, creating strong demand for the U.S. healthcare API market. As hospitals and outpatient facilities modernize infrastructure to support electronic health records (EHRs), telehealth, remote patient monitoring, and AI-powered diagnostics, APIs serve as the essential backbone enabling system integration and real-time data exchange. From enhancing patient portals to automating clinical workflows and improving care coordination, APIs help providers bridge siloed systems. Initiatives such as cloud migration, interoperability mandates, and digital front-door strategies further amplify this demand. Providers are increasingly seeking standards-based, scalable APIs to integrate third-party apps, ensure compliance, and deliver connected, patient-centered care.
Advanced healthcare IT infrastructure, growing strategies and initiatives by key market players, investments supporting telemedicine's growth, and a growing emphasis on data interoperability. For instance, in March 2025, Alphabet Inc. launched global FHIR-compliant Medical Records APIs in Health Connect, enabling apps to securely read and write clinical data such as allergies, medications, immunizations, and lab results, now supporting over 50 health data types on-device. Hospitals, clinics, insurers, and digital health platforms across the country increasingly rely on APIs to streamline data exchange, enhance care coordination, and improve patient engagement through integrated digital services. Some of the APIs used by healthcare providers in the U.S. include:
- Human API is a consumer-centric health data platform that integrates with 90% of US hospitals and over 300 wearable devices and fitness apps.
- Doximity has emerged as the largest network of healthcare professionals in the U.S., connecting over 70% of physicians, nurse practitioners, physician
Moreover, the shift toward patient-centric healthcare and government initiatives such as the 21st Century Cures Act in the U.S., which requires open API access to patient data, also adds to the key factors driving the market growth. APIs empower patients by enabling them to access and manage their health data through mobile apps and wearable devices. This increasing emphasis on using APIs likely to drive the demand for APIs and market growth.
U.S. Healthcare API Market Report Segmentation
This report forecasts revenue growth at country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, the analyst has segmented the U.S. healthcare API market report based on services, deployment model, and end use.Services Outlook (Revenue, USD Million, 2021-2033)
- EHR access
- Appointments
- Remote Patient Monitoring
- Payment
- Wearable medical device
Deployment Model Outlook (Revenue, USD Million, 2021-2033)
- Cloud Based
- On Premise
End Use Outlook (Revenue, USD Million, 2021-2033)
- Healthcare payers
- Providers
- Patients
- Vendors
Why should you buy this report?
- Comprehensive Market Analysis: Gain detailed insights into the market across major regions and segments.
- Competitive Landscape: Explore the market presence of key players.
- Future Trends: Discover the pivotal trends and drivers shaping the future of the market.
- Actionable Recommendations: Utilize insights to uncover new revenue streams and guide strategic business decisions.
This report addresses:
- Market intelligence to enable effective decision-making
- Market estimates and forecasts from 2018 to 2030
- Growth opportunities and trend analyses
- Segmental and regional revenue forecasts for market assessment
- Competition strategy and market share analysis
- Product innovation listings for you to stay ahead of the curve
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Table of Contents
Chapter 1. Methodology and Scope
Chapter 2. Executive Summary
Chapter 3. Market Variables, Trends, & Scope
Chapter 4. U.S. Healthcare API Market: Services Estimates & Trend Analysis
Chapter 5. U.S. Healthcare API Market: Deployment Model Estimates & Trend Analysis
Chapter 6. U.S. Healthcare API Market: End Use Estimates & Trend Analysis
Chapter 7. Competitive Landscape
List of Tables
List of Figures
Companies Mentioned
The leading players profiled in this U.S. Healthcare API market report include:- pple, Inc.
- thenahealth
- erner Corporation (Oracle)
- icrosoft
- pic Systems Corporation
- ClinicalWorks
- eradigm LLC
- reenway Health, LLC
- ractice Fusion, Inc.
- alesforce, Inc.
- BM
- lphabet Inc.
Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 90 |
| Published | September 2025 |
| Forecast Period | 2025 - 2033 |
| Estimated Market Value ( USD | $ 303.3 Million |
| Forecasted Market Value ( USD | $ 413.7 Million |
| Compound Annual Growth Rate | 4.0% |
| Regions Covered | United States |
| No. of Companies Mentioned | 13 |
