Next-Generation Sequencing Informatics Market Report 2025

The next-generation sequencing informatics market size has grown rapidly in recent years. It will grow from $8.73 billion in 2024 to $10.23 billion in 2025 at a compound annual growth rate (CAGR) of 17.1%. The growth in the historic period can be linked to increasing adoption of personalized medicine, expanding applications of next-generation sequencing (NGS) in disease diagnosis, rising demand for biomarker discovery, growing focus on genomic research, and greater integration of artificial intelligence (AI) in sequencing informatics.

The next-generation sequencing informatics market size is expected to see rapid growth in the next few years. It will grow to $19.0 billion in 2029 at a compound annual growth rate (CAGR) of 16.7%. The growth in the forecast period can be linked to greater use of sequencing informatics in clinical diagnostics, increased implementation of artificial intelligence (AI) in drug discovery, higher demand for multi-omics data analysis, wider adoption of cloud-based next-generation sequencing (NGS) analytics, and growing emphasis on precision medicine. Key trends during the forecast period include advancements in cloud-based NGS solutions, innovation in data analysis tools for sequencing informatics, integration of AI and machine learning (ML) for genomic data interpretation, development of visualization and workflow management systems, and progress in personalized medicine.

The growing adoption of personalized medicine is expected to drive the expansion of the next-generation sequencing (NGS) informatics market. Personalized medicine customizes treatment and prevention strategies based on an individual’s genetic profile, lifestyle, and environment. This approach has gained traction due to advancements in genomics, which allow for the precise identification of genetic variations and the development of personalized treatments. NGS informatics supports personalized medicine by enabling comprehensive analysis of genomic data, making it well-suited for precision healthcare and tailored treatment strategies. By identifying genetic variations and predicting disease risk, NGS informatics reduces diagnostic uncertainty, enhances clinical decision-making, and improves patient outcomes. For example, in February 2024, the Personalized Medicine Coalition reported that the U.S. Food and Drug Administration approved 26 new personalized medicines in 2023, a substantial increase from the 12 approved in 2022. This trend reflects the increasing adoption of personalized medicine and is fueling the growth of the NGS informatics market.

Leading companies in the NGS informatics market are focusing on developing advanced solutions, such as cloud-based platforms, to enhance scalability, data security, and streamline genomic workflows. Cloud-based platforms are digital infrastructures that allow researchers and clinicians to store, process, and analyze large amounts of sequencing data either remotely or within local institutional environments. For example, in March 2023, Illumina Inc., a U.S.-based biotechnology company, introduced Connected Insights, a cloud-based software designed for the tertiary analysis of clinical NGS data. This platform streamlines genomic data interpretation and reporting, integrates more than 45 third-party knowledge sources, and shortens turnaround times for clinical reports. It automates variant interpretation and report generation, reducing manual effort and standardizing workflows across various assay types, such as comprehensive genomic profiling (CGP), whole-exome sequencing (WES), and transcriptomic data.

In May 2025, GeneDx Inc., a U.S.-based biotechnology company, acquired Fabric Genomics Inc., a company specializing in NGS informatics. This acquisition strengthens GeneDx’s capabilities in AI-driven genomic interpretation and expands access to advanced NGS solutions. It also enhances the company's offerings in rare disease diagnostics, hereditary risk assessment, and precision medicine. Fabric Genomics’ expertise in next-generation sequencing informatics will support GeneDx’s efforts to advance genomic solutions and improve patient outcomes in the rapidly growing field of personalized medicine.

Major players in the next-generation sequencing informatics market are F. Hoffmann-La Roche Ltd., Thermo Fisher Scientific Inc., Eurofins Scientific SE, Agilent Technologies, Illumina Inc., Bio-Rad Laboratories Inc., QIAGEN N.V., BGI Genomics Co. Ltd., Oxford Nanopore Technologies Ltd., GeneDx Holdings Corp., Macrogen Inc., MedGenome Inc., Sophia Genetics SA, DNAnexus Inc., Clear Labs, DNASTAR Inc., Sapio Sciences Inc., Geneious Biomatters Ltd., Genomatix Software GmbH, and CosmosID Inc.

North America was the largest region in the next-generation sequencing informatics market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in next-generation sequencing informatics report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa. The countries covered in the next-generation sequencing informatics market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report’s Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The fast surge in U.S. tariffs and the trade tensions that followed in spring 2025 are heavily affecting the medical equipment sector, particularly for imported imaging machine components, surgical-grade stainless steel, and plastic disposables. Hospitals and clinics resist price hikes, pressuring manufacturers’ margins. Regulatory hurdles compound the problem, as tariff-related supplier changes often require re-certification of devices, delaying time-to-market. Companies are mitigating risks by dual-sourcing critical parts, expanding domestic production of commoditized items, and accelerating R&D in cost-efficient materials.

Next-generation sequencing (NGS) informatics refers to the use of computational tools and algorithms to process, analyze, and interpret large volumes of DNA or RNA sequencing data generated by next-generation sequencing technologies. Its primary objective is to efficiently identify genetic variations, mutations, and expression patterns, supporting applications in genomics research, personalized medicine, diagnostics, and drug development.

The main offerings of next-generation sequencing (NGS) informatics include software, platforms, and services. Software encompasses computer programs and bioinformatics tools designed to process, analyze, interpret, and visualize large-scale genomic data from NGS platforms. The offerings cover storage and computing solutions, commercial data analysis, interpretation and reporting tools, informatics services, and laboratory information management systems (LIMS), and can be deployed via cloud, on-premises, or hybrid systems. These informatics solutions are applied in research and development, clinical diagnostics, drug discovery, and agrigenomics, serving academic and research institutions, pharmaceutical and biotechnology companies, hospitals and clinical laboratories, and agricultural biotech organizations.

The next-generation sequencing informatics market research report is one of a series of new reports that provides next-generation sequencing informatics market statistics, including the next-generation sequencing informatics industry global market size, regional shares, competitors with the next-generation sequencing informatics market share, detailed next-generation sequencing informatics market segments, market trends, and opportunities, and any further data you may need to thrive in the next-generation sequencing informatics industry. This next-generation sequencing informatics market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The next-generation sequencing informatics market includes revenues earned by entities through data analysis and interpretation, bioinformatics pipeline development, genomic data storage and management, variant annotation and prioritization, and reporting and visualization. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values and are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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