Library Preparation and Target Enrichment for Next-Generation Sequencing Product Market Report 2025

The library preparation and target enrichment for next-generation sequencing product market size has grown rapidly in recent years. It will grow from $3.06 billion in 2024 to $3.43 billion in 2025 at a compound annual growth rate (CAGR) of 12.1%. The growth during the historic period was driven by increasing adoption of whole genome sequencing, rising demand for automation in library preparation, expanding applications of next-generation sequencing in rare disease research, greater integration of multi-omics approaches, and rising investments in genomic data analysis tools.

The library preparation and target enrichment for next-generation sequencing product market size is expected to see rapid growth in the next few years. It will grow to $5.34 billion in 2029 at a compound annual growth rate (CAGR) of 11.7%. Growth during the forecast period is fueled by increasing adoption of precision medicine, rising investments in genomic research, expanding use of next-generation sequencing in clinical diagnostics, and greater government support for genomics initiatives. The primary trends in the forecast period include advancements in automation of library preparation, development of portable and real-time sequencing platforms, innovations in hybrid capture and CRISPR-based enrichment techniques, integration of bioinformatics and AI, and the creation of eco-friendly and sustainable sequencing reagents.

The growing demand for personalized medicine is expected to drive the expansion of the library preparation and target enrichment for next-generation sequencing product market in the coming years. Personalized medicine is a healthcare approach that customizes treatment and prevention strategies based on an individual’s genetic makeup, lifestyle, and environment. The rise in personalized medicine adoption is largely due to advances in genomics, which facilitate the precise identification of genetic variations and enable tailored treatments. Library preparation and target enrichment products for next-generation sequencing support personalized medicine by allowing accurate and efficient genomic analysis, making them essential for detecting patient-specific genetic variations. These tools streamline workflows, reduce experimental complexity, and improve diagnostic accuracy, leading to better-targeted treatment plans. For example, in February 2024, the Personalized Medicine Coalition (PMC), a US-based nonprofit, reported that the U.S. Food and Drug Administration (FDA) approved 26 new personalized medicines in 2023, a notable increase from the 12 approved in 2022. Consequently, the rising demand for personalized medicine is fueling the growth of the library preparation and target enrichment product market.

Leading companies in the library preparation and target enrichment for next-generation sequencing market are focusing on developing innovative solutions, such as multimodal NGS library preparation kits, to enhance sequencing efficiency, specificity, and coverage. A multimodal next-generation sequencing (NGS) library preparation kit is a laboratory tool that enables the simultaneous preparation of DNA and RNA sequencing libraries from a single biological sample. This approach reduces material usage, simplifies workflows, and shortens turnaround times while supporting downstream target enrichment. For instance, in May 2024, QIAGEN N.V., a biotechnology company based in the Netherlands, launched the QIAseq Multimodal DNA or RNA Library Kit. This kit offers the first integrated method for preparing both DNA and RNA sequencing libraries from a single sample, using diverse materials such as blood, formalin-fixed paraffin-embedded tissue, and cell-free DNA. It maintains high sensitivity and variant detection capabilities while consolidating multiple laboratory workflows into one platform, reducing preparation time, and ensuring compatibility with various sequencing instruments and hybrid-capture enrichment panels. This innovation supports advanced research in complex diseases such as cancer.

In January 2023, Agilent Technologies Inc., a US-based life sciences and diagnostics company, acquired Avida Biomed Inc. for an undisclosed amount. Through this acquisition, Agilent aims to expand its NGS library preparation and target enrichment capabilities, bolstering its presence in cancer research, precision medicine, and advanced genomic workflows. Avida Biomed Inc. is a US-based biotechnology firm specializing in products for NGS library preparation and target enrichment.

Major players in the library preparation and target enrichment for next-generation sequencing product market are F. Hoffmann-La Roche AG, Thermo Fisher Scientific Inc., Danaher Corporation, Becton Dickinson And Company, Eurofins Scientific SE, Agilent Technologies Inc., Illumina Inc., Sysmex Corporation, Bruker Corporation, Revvity Inc., Bio-Rad Laboratories Inc., QIAGEN N.V., Tecan Group Ltd., Hamilton Company, BGI Genomics Co. Ltd., Takara Bio Inc., Twist Bioscience Corporation, Pacific Biosciences of California Inc., New England Biolabs Inc., Zymo Research Corporation, Lexogen GmbH, and Paragon Genomics Inc.

North America was the largest region in the library preparation and target enrichment for next generation sequencing product market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in library preparation and target enrichment for next-generation sequencing product report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa. The countries covered in the library preparation and target enrichment for next-generation sequencing product market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report’s Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The fast surge in U.S. tariffs and the trade tensions that followed in spring 2025 are heavily affecting the medical equipment sector, particularly for imported imaging machine components, surgical-grade stainless steel, and plastic disposables. Hospitals and clinics resist price hikes, pressuring manufacturers’ margins. Regulatory hurdles compound the problem, as tariff-related supplier changes often require re-certification of devices, delaying time-to-market. Companies are mitigating risks by dual-sourcing critical parts, expanding domestic production of commoditized items, and accelerating R&D in cost-efficient materials.

Library preparation and target enrichment for next-generation sequencing (NGS) involve converting DNA or RNA samples into a format compatible with sequencing platforms and selectively capturing regions of interest. These products enable the generation of high-quality, representative libraries and enrichment of specific genomic targets, allowing accurate, efficient, and cost-effective sequencing of desired regions.

The primary product types of library preparation and target enrichment for NGS are library preparation kits, target enrichment kits, instrument systems, reagents, and consumables and accessories. Library preparation kits are used to convert DNA or RNA into sequencing-ready libraries, enabling precise and efficient sequencing of genetic material. Technologies utilized include targeted sequencing, whole exome sequencing, whole genome sequencing, RNA sequencing, and single-cell sequencing, covering workflow stages from sample preparation and library construction to enrichment, sequencing, and data analysis. These products are applied in clinical diagnostics, research and development, forensic applications, and others, serving end users such as academic and research institutions, clinical laboratories, pharmaceutical and biotech companies, hospitals and diagnostic centers, and government and non-profit organizations.

The library preparation and target enrichment for next-generation sequencing product market research report is one of a series of new reports that provides library preparation and target enrichment for next-generation sequencing product market statistics, including library preparation and target enrichment for next-generation sequencing product industry global market size, regional shares, competitors with a library preparation and target enrichment for next-generation sequencing product market share, detailed library preparation and target enrichment for next-generation sequencing product market segments, market trends and opportunities, and any further data you may need to thrive in the library preparation and target enrichment for next-generation sequencing product industry. This library preparation and target enrichment for next-generation sequencing product market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The library preparation and target enrichment for next-generation sequencing product market consists of revenues earned by entities by providing services such as target enrichment service outsourcing, custom assay design, sample quality check and quantification, sequencing service bureaus, and bioinformatics and data interpretation services. The market value includes the value of related goods sold by the service provider or included within the service offering. The library preparation and target enrichment for next-generation sequencing products market also includes sales of sample storage solutions, DNA/RNA stabilizers, RNA depletion kits, cDNA synthesis kits, molecular indexing tools, sequencing adapters for specialized applications, and barcoding kits for multiplexing. Values in this market are ‘factory gate’ values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values and are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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