The library preparation (prep) system market size has grown rapidly in recent years. It will grow from $1.37 billion in 2025 to $1.53 billion in 2026 at a compound annual growth rate (CAGR) of 11.8%. The growth in the historic period can be attributed to expansion of NGS adoption, growth in genomic research funding, increasing sequencing accuracy needs, rise of clinical genomics, declining sequencing costs.
The library preparation (prep) system market size is expected to see rapid growth in the next few years. It will grow to $2.36 billion in 2030 at a compound annual growth rate (CAGR) of 11.5%. The growth in the forecast period can be attributed to growth of precision medicine, rising clinical sequencing volumes, integration of automated platforms, expansion of population genomics, demand for faster turnaround times. Major trends in the forecast period include automation of library preparation workflows, rising demand for high-throughput sequencing, growth of single-cell sequencing prep, standardization of genomic workflows, increased focus on reproducibility.
The increasing adoption of personalized medicine is expected to drive the growth of the library preparation (prep) system market in the coming years. Personalized medicine is a medical approach that tailors treatment and prevention strategies based on an individual’s unique genetic profile, lifestyle, and environment. This shift toward personalized medicine is largely due to advancements in genomics, which enable precise identification of genetic variations and the development of treatments that are specifically tailored to individuals. Library preparation (prep) systems play a crucial role in personalized medicine by enabling the accurate preparation of DNA and RNA samples, making them essential for precise genomic analysis. These systems streamline complex workflows, reduce errors, and accelerate the development of targeted therapies, ultimately improving patient-specific treatment outcomes. For example, in February 2024, the Personalized Medicine Coalition (PMC) reported that the FDA approved 26 new personalized medicines in 2023, a notable increase from 12 in 2022. As a result, the growing adoption of personalized medicine is driving the expansion of the library preparation (prep) system market.
Companies in the library preparation (prep) system market are focusing on developing advanced products, such as multimodal library preparation kits, to increase efficiency, enhance research capabilities, and minimize manual effort and sample material requirements. Multimodal library preparation kits are integrated solutions that allow for the simultaneous processing of both DNA and RNA from a single sample, enabling comprehensive genomic and transcriptomic analysis. For instance, in May 2024, Qiagen N.V., a Netherlands-based biotechnology company, introduced the QIAseq Multimodal DNA or RNA library kit. This innovative next-generation sequencing (NGS) kit is the first of its kind designed to prepare both DNA and RNA libraries from a single sample. The solution facilitates seamless preparation for whole genome sequencing (WGS) and whole transcriptome sequencing (WTS), featuring automated workflow integration and optimized chemistry to enable simultaneous DNA and RNA processing. This significantly reduces turnaround times and minimizes the use of sample material without requiring operator intervention.
In December 2023, PerkinElmer Inc., a US-based biotechnology firm, acquired Covaris LLC to enhance its NGS sample preparation capabilities. Through this acquisition, PerkinElmer aims to expand its NGS portfolio by adding Covaris’ library prep systems and AFA instruments, improving its ability to provide high-quality, automated sample preparation solutions. Covaris LLC is a US-based biotechnology company that specializes in library preparation systems for next-generation sequencing.
Major companies operating in the library preparation (prep) system market are F. Hoffmann-La Roche AG, Thermo Fisher Scientific Inc., Siemens Healthineers AG, Agilent Technologies Inc., Illumina Inc., Bio-Rad Laboratories Inc., QIAGEN N.V., Tecan Group Ltd., GenScript Biotech Corporation, Promega Corporation, Takara Bio Inc., Oxford Nanopore Technologies Limited, Pacific Biosciences of California Inc., New England Biolabs Inc., Singleron Biotechnologies Co. Ltd., Bionano Genomics Inc., Automata Technologies Ltd., Zymo Research Corporation, Dolomite Bio Limited, Micronit Microtechnologies B.V., Opentrons Labworks Inc., EpigenDx Inc.
North America was the largest region in the library preparation (prep) system market in 2025. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the library preparation (prep) system market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the library preparation (prep) system market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
Tariffs have increased costs of imported reagents, automation instruments, and precision components used in library prep systems. North America and Europe are most affected due to reliance on Asia-Pacific suppliers. This has increased operational costs for research labs. However, tariffs are encouraging localized reagent production, automated system innovation, and supply chain resilience.
The library preparation (prep) system market research report is one of a series of new reports that provides library preparation (prep) system market statistics, including library preparation (prep) system industry global market size, regional shares, competitors with a library preparation (prep) system market share, detailed library preparation (prep) system market segments, market trends and opportunities, and any further data you may need to thrive in the library preparation (prep) system industry. This library preparation (prep) system market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
A library preparation (prep) system is a laboratory platform or workflow designed to process nucleic acids for sequencing or other genomic applications. It includes steps such as fragmentation, adapter ligation, amplification, and purification to convert raw biological samples into sequence-ready libraries. The system ensures high-quality, consistent, and efficient sample preparation, enabling accurate and reproducible downstream sequencing and analysis.
The primary product types of library preparation (prep) systems are manual and automated library prep systems. Manual library prep systems are hand-operated kits and protocols used to prepare DNA or RNA samples for sequencing, requiring direct human handling rather than automation. These systems support technologies such as next-generation sequencing (NGS), Sanger sequencing, and microarrays, and are applied across workflow stages including sample preparation, library preparation, quality control, and data analysis. Key applications include whole genome sequencing, targeted sequencing, RNA sequencing, exome sequencing, and metagenomics, serving academic and research institutes, pharmaceutical and biotechnology companies, clinical laboratories, and diagnostic laboratories.
The library preparation (prep) system market consists of revenues earned by entities by providing services such as nucleic acid extraction, library construction, sequencing-ready library generation, and workflow automation support. The market value includes the value of related goods sold by the service provider or included within the service offering. The library prep system market also includes sales of quality control (QC) tools for library prep, single-cell library preparation kits, adapter ligation kits, automation-ready library preparation kits, methylation library preparation kits, and whole-genome amplification kits. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
This product will be delivered within 1-3 business days.
The library preparation (prep) system market size is expected to see rapid growth in the next few years. It will grow to $2.36 billion in 2030 at a compound annual growth rate (CAGR) of 11.5%. The growth in the forecast period can be attributed to growth of precision medicine, rising clinical sequencing volumes, integration of automated platforms, expansion of population genomics, demand for faster turnaround times. Major trends in the forecast period include automation of library preparation workflows, rising demand for high-throughput sequencing, growth of single-cell sequencing prep, standardization of genomic workflows, increased focus on reproducibility.
The increasing adoption of personalized medicine is expected to drive the growth of the library preparation (prep) system market in the coming years. Personalized medicine is a medical approach that tailors treatment and prevention strategies based on an individual’s unique genetic profile, lifestyle, and environment. This shift toward personalized medicine is largely due to advancements in genomics, which enable precise identification of genetic variations and the development of treatments that are specifically tailored to individuals. Library preparation (prep) systems play a crucial role in personalized medicine by enabling the accurate preparation of DNA and RNA samples, making them essential for precise genomic analysis. These systems streamline complex workflows, reduce errors, and accelerate the development of targeted therapies, ultimately improving patient-specific treatment outcomes. For example, in February 2024, the Personalized Medicine Coalition (PMC) reported that the FDA approved 26 new personalized medicines in 2023, a notable increase from 12 in 2022. As a result, the growing adoption of personalized medicine is driving the expansion of the library preparation (prep) system market.
Companies in the library preparation (prep) system market are focusing on developing advanced products, such as multimodal library preparation kits, to increase efficiency, enhance research capabilities, and minimize manual effort and sample material requirements. Multimodal library preparation kits are integrated solutions that allow for the simultaneous processing of both DNA and RNA from a single sample, enabling comprehensive genomic and transcriptomic analysis. For instance, in May 2024, Qiagen N.V., a Netherlands-based biotechnology company, introduced the QIAseq Multimodal DNA or RNA library kit. This innovative next-generation sequencing (NGS) kit is the first of its kind designed to prepare both DNA and RNA libraries from a single sample. The solution facilitates seamless preparation for whole genome sequencing (WGS) and whole transcriptome sequencing (WTS), featuring automated workflow integration and optimized chemistry to enable simultaneous DNA and RNA processing. This significantly reduces turnaround times and minimizes the use of sample material without requiring operator intervention.
In December 2023, PerkinElmer Inc., a US-based biotechnology firm, acquired Covaris LLC to enhance its NGS sample preparation capabilities. Through this acquisition, PerkinElmer aims to expand its NGS portfolio by adding Covaris’ library prep systems and AFA instruments, improving its ability to provide high-quality, automated sample preparation solutions. Covaris LLC is a US-based biotechnology company that specializes in library preparation systems for next-generation sequencing.
Major companies operating in the library preparation (prep) system market are F. Hoffmann-La Roche AG, Thermo Fisher Scientific Inc., Siemens Healthineers AG, Agilent Technologies Inc., Illumina Inc., Bio-Rad Laboratories Inc., QIAGEN N.V., Tecan Group Ltd., GenScript Biotech Corporation, Promega Corporation, Takara Bio Inc., Oxford Nanopore Technologies Limited, Pacific Biosciences of California Inc., New England Biolabs Inc., Singleron Biotechnologies Co. Ltd., Bionano Genomics Inc., Automata Technologies Ltd., Zymo Research Corporation, Dolomite Bio Limited, Micronit Microtechnologies B.V., Opentrons Labworks Inc., EpigenDx Inc.
North America was the largest region in the library preparation (prep) system market in 2025. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the library preparation (prep) system market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the library preparation (prep) system market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
Tariffs have increased costs of imported reagents, automation instruments, and precision components used in library prep systems. North America and Europe are most affected due to reliance on Asia-Pacific suppliers. This has increased operational costs for research labs. However, tariffs are encouraging localized reagent production, automated system innovation, and supply chain resilience.
The library preparation (prep) system market research report is one of a series of new reports that provides library preparation (prep) system market statistics, including library preparation (prep) system industry global market size, regional shares, competitors with a library preparation (prep) system market share, detailed library preparation (prep) system market segments, market trends and opportunities, and any further data you may need to thrive in the library preparation (prep) system industry. This library preparation (prep) system market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
A library preparation (prep) system is a laboratory platform or workflow designed to process nucleic acids for sequencing or other genomic applications. It includes steps such as fragmentation, adapter ligation, amplification, and purification to convert raw biological samples into sequence-ready libraries. The system ensures high-quality, consistent, and efficient sample preparation, enabling accurate and reproducible downstream sequencing and analysis.
The primary product types of library preparation (prep) systems are manual and automated library prep systems. Manual library prep systems are hand-operated kits and protocols used to prepare DNA or RNA samples for sequencing, requiring direct human handling rather than automation. These systems support technologies such as next-generation sequencing (NGS), Sanger sequencing, and microarrays, and are applied across workflow stages including sample preparation, library preparation, quality control, and data analysis. Key applications include whole genome sequencing, targeted sequencing, RNA sequencing, exome sequencing, and metagenomics, serving academic and research institutes, pharmaceutical and biotechnology companies, clinical laboratories, and diagnostic laboratories.
The library preparation (prep) system market consists of revenues earned by entities by providing services such as nucleic acid extraction, library construction, sequencing-ready library generation, and workflow automation support. The market value includes the value of related goods sold by the service provider or included within the service offering. The library prep system market also includes sales of quality control (QC) tools for library prep, single-cell library preparation kits, adapter ligation kits, automation-ready library preparation kits, methylation library preparation kits, and whole-genome amplification kits. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
This product will be delivered within 1-3 business days.
Table of Contents
1. Executive Summary
2. Library Preparation (Prep) System Market Characteristics
3. Library Preparation (Prep) System Market Supply Chain Analysis
4. Global Library Preparation (Prep) System Market Trends and Strategies
5. Library Preparation (Prep) System Market Analysis of End Use Industries
7. Global Library Preparation (Prep) System Strategic Analysis Framework, Current Market Size, Market Comparisons and Growth Rate Analysis
8. Global Library Preparation (Prep) System Total Addressable Market (TAM) Analysis for the Market
9. Library Preparation (Prep) System Market Segmentation
10. Library Preparation (Prep) System Market Regional and Country Analysis
11. Asia-Pacific Library Preparation (Prep) System Market
12. China Library Preparation (Prep) System Market
13. India Library Preparation (Prep) System Market
14. Japan Library Preparation (Prep) System Market
15. Australia Library Preparation (Prep) System Market
16. Indonesia Library Preparation (Prep) System Market
17. South Korea Library Preparation (Prep) System Market
18. Taiwan Library Preparation (Prep) System Market
19. South East Asia Library Preparation (Prep) System Market
20. Western Europe Library Preparation (Prep) System Market
21. UK Library Preparation (Prep) System Market
22. Germany Library Preparation (Prep) System Market
23. France Library Preparation (Prep) System Market
24. Italy Library Preparation (Prep) System Market
25. Spain Library Preparation (Prep) System Market
26. Eastern Europe Library Preparation (Prep) System Market
27. Russia Library Preparation (Prep) System Market
28. North America Library Preparation (Prep) System Market
29. USA Library Preparation (Prep) System Market
30. Canada Library Preparation (Prep) System Market
31. South America Library Preparation (Prep) System Market
32. Brazil Library Preparation (Prep) System Market
33. Middle East Library Preparation (Prep) System Market
34. Africa Library Preparation (Prep) System Market
36. Library Preparation (Prep) System Market Competitive Landscape and Company Profiles
37. Library Preparation (Prep) System Market Other Major and Innovative Companies
40. Library Preparation (Prep) System Market High Potential Countries, Segments and Strategies
41. Appendix
List of Tables
Executive Summary
Library Preparation (Prep) System Market Global Report 2026 provides strategists, marketers and senior management with the critical information they need to assess the market.This report focuses library preparation (prep) system market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
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Description
Where is the largest and fastest growing market for library preparation (prep) system? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The library preparation (prep) system market global report answers all these questions and many more.The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, total addressable market (TAM), market attractiveness score (MAS), competitive landscape, market shares, company scoring matrix, trends and strategies for this market. It traces the market’s historic and forecast market growth by geography.
- The market characteristics section of the report defines and explains the market. This section also examines key products and services offered in the market, evaluates brand-level differentiation, compares product features, and highlights major innovation and product development trends.
- The supply chain analysis section provides an overview of the entire value chain, including key raw materials, resources, and supplier analysis. It also provides a list competitor at each level of the supply chain.
- The updated trends and strategies section analyses the shape of the market as it evolves and highlights emerging technology trends such as digital transformation, automation, sustainability initiatives, and AI-driven innovation. It suggests how companies can leverage these advancements to strengthen their market position and achieve competitive differentiation.
- The regulatory and investment landscape section provides an overview of the key regulatory frameworks, regularity bodies, associations, and government policies influencing the market. It also examines major investment flows, incentives, and funding trends shaping industry growth and innovation.
- The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
- The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.
- The total addressable market (TAM) analysis section defines and estimates the market potential compares it with the current market size, and provides strategic insights and growth opportunities based on this evaluation.
- The market attractiveness scoring section evaluates the market based on a quantitative scoring framework that considers growth potential, competitive dynamics, strategic fit, and risk profile. It also provides interpretive insights and strategic implications for decision-makers.
- Market segmentations break down the market into sub markets.
- The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth.
- Expanded geographical coverage includes Taiwan and Southeast Asia, reflecting recent supply chain realignments and manufacturing shifts in the region. This section analyzes how these markets are becoming increasingly important hubs in the global value chain.
- The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
- The company scoring matrix section evaluates and ranks leading companies based on a multi-parameter framework that includes market share or revenues, product innovation, and brand recognition.
Report Scope
Markets Covered:
1) By Product Type: Manual Library Prep Systems; Automated Library Prep Systems2) By Technology: Next-Generation Sequencing (NGS); Sanger Sequencing; Microarray
3) By Workflow Stage: Sample Preparation; Library Preparation; Quality Control; Data Analysis
4) By Application: Whole Genome Sequencing; Targeted Sequencing; Ribonucleic Acid (RNA) Sequencing; Exome Sequencing; Metagenomics
5) By End User: Academic And Research Institutes; Pharmaceutical And Biotechnology Companies; Clinical Laboratories; Diagnostics Laboratories
Subsegments:
1) By Manual Library Prep Systems: Deoxyribonucleic Acid (DNA) Library Prep Kits; Ribonucleic Acid (RNA) Library Prep Kits; Amplicon Library Prep Kits; Targeted Library Prep Kits; Low-input Or Single-cell Library Prep Kits2) By Automated Library Prep Systems: Automated Deoxyribonucleic Acid (DNA) Library Prep Instruments; Automated Ribonucleic Acid (RNA) Library Prep Instruments; High-throughput Library Prep Platforms; Benchtop Automated Library Prep Systems; Integrated NGS Workflow Systems
Companies Mentioned: F. Hoffmann-La Roche AG; Thermo Fisher Scientific Inc.; Siemens Healthineers AG; Agilent Technologies Inc.; Illumina Inc.; Bio-Rad Laboratories Inc.; QIAGEN N.V.; Tecan Group Ltd.; GenScript Biotech Corporation; Promega Corporation; Takara Bio Inc.; Oxford Nanopore Technologies Limited; Pacific Biosciences of California Inc.; New England Biolabs Inc.; Singleron Biotechnologies Co. Ltd.; Bionano Genomics Inc.; Automata Technologies Ltd.; Zymo Research Corporation; Dolomite Bio Limited; Micronit Microtechnologies B.V.; Opentrons Labworks Inc.; EpigenDx Inc.
Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Taiwan; Russia; South Korea; UK; USA; Canada; Italy; Spain
Regions: Asia-Pacific; South East Asia; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
Time Series: Five years historic and ten years forecast.
Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita.
Data Segmentation: Country and regional historic and forecast data, market share of competitors, market segments.
Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.
Delivery Format: Word, PDF or Interactive Report + Excel Dashboard
Added Benefits:
- Bi-Annual Data Update
- Customisation
- Expert Consultant Support
Companies Mentioned
The companies featured in this Library Preparation (Prep) System market report include:- F. Hoffmann-La Roche AG
- Thermo Fisher Scientific Inc.
- Siemens Healthineers AG
- Agilent Technologies Inc.
- Illumina Inc.
- Bio-Rad Laboratories Inc.
- QIAGEN N.V.
- Tecan Group Ltd.
- GenScript Biotech Corporation
- Promega Corporation
- Takara Bio Inc.
- Oxford Nanopore Technologies Limited
- Pacific Biosciences of California Inc.
- New England Biolabs Inc.
- Singleron Biotechnologies Co. Ltd.
- Bionano Genomics Inc.
- Automata Technologies Ltd.
- Zymo Research Corporation
- Dolomite Bio Limited
- Micronit Microtechnologies B.V.
- Opentrons Labworks Inc.
- EpigenDx Inc.
Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 250 |
| Published | February 2026 |
| Forecast Period | 2026 - 2030 |
| Estimated Market Value ( USD | $ 1.53 Billion |
| Forecasted Market Value ( USD | $ 2.36 Billion |
| Compound Annual Growth Rate | 11.5% |
| Regions Covered | Global |
| No. of Companies Mentioned | 23 |
