Hyaluronic Acid Market Report 2025

The hyaluronic acid market size has grown strongly in recent years. It will grow from $7.18 billion in 2024 to $7.84 billion in 2025 at a compound annual growth rate (CAGR) of 9.1%. The growth in the historic period is attributed to rising demand for minimally invasive aesthetic procedures, increasing prevalence of osteoarthritis, a growing geriatric population, higher consumer spending on anti-aging products, and a rising incidence of dry-eye disease.

The hyaluronic acid market size is expected to see strong growth in the next few years. It will grow to $10.98 billion in 2029 at a compound annual growth rate (CAGR) of 8.8%. The growth in the forecast period is driven by increasing research and development and regulatory approvals, expanding indications and longer-lasting crosslinked hyaluronic acid (HA) products, greater healthcare access, growth in e-commerce and direct-to-consumer (D2C) beauty channels, and improved biotechnological production yields. Key trends in the forecast period include advancements in crosslinking technologies, progress in fermentation-based production, integration of HA with nanotechnology, innovations in technology-driven skincare formulations, and adoption of HA technologies in ophthalmology.

The growing number of aesthetic procedures is expected to drive the expansion of the hyaluronic acid market. Aesthetic procedures are treatments aimed at enhancing appearance, improving features, and rejuvenating the skin or body for a more youthful and balanced look. This rise is largely due to technological improvements that have made these treatments safer, less invasive, and more effective, leading to increased adoption. Hyaluronic acid plays a key role in these procedures by restoring facial volume, minimizing wrinkles, and enhancing skin hydration for smoother, more youthful skin. For example, in June 2025, the American Society of Plastic Surgeons reported that over 800,000 patients underwent aesthetic procedures in 2024 to support their health goals. Tummy tucks were the second most popular procedure, showing a 1% increase from 2023, while facelifts and forehead lifts each saw a 1% rise. This upward trend in aesthetic procedures is contributing to the growth of the hyaluronic acid market.

Leading companies in the hyaluronic acid market are focusing on innovations such as cationic hyaluronic acid to improve skin adhesion, enhance hydration, and expand use in rinse-off products. Cationic hyaluronic acid is a chemically modified version with a positive charge that strengthens adhesion, improves interaction with skin cells, and enhances stability, making it suitable for advanced medical and cosmetic use. In March 2023, Givaudan S.A., a chemicals company based in Switzerland, introduced PrimalHyal Hydra, a cationic hyaluronic acid developed through white biotechnology. This active ingredient delivers instant hydration after one application and maintains moisturization for up to four days, performing at least twice as effectively as standard hyaluronic acid. It works in both rinse-off and leave-on skincare products and strengthens the skin barrier by boosting lipid and protein production. Clinically tested, it is suitable for various skincare products including lotions, shower gels, and masks, offering long-lasting hydration with strong skin adhesion benefits.

In July 2025, Waldencast plc, a beauty and wellness company based in the UK, acquired Novaestiq Corp. for an undisclosed amount. This acquisition aims to expand Obagi Medical’s portfolio beyond medical-grade skincare into the fast-growing U.S. dermal filler market. The move significantly increases its market reach and positions Obagi Medical as a leader in integrated skincare and aesthetic solutions. Novaestiq Corp., based in the U.S., specializes in developing and commercializing aesthetic and dermatological products, with a focus on hyaluronic acid dermal fillers.

Major players in the hyaluronic acid market are AbbVie Inc., L'Oréal S.A., LG Chem Ltd., Shiseido Company Limited, Givaudan SA, Zimmer Biomet Holdings Inc., Grifols S.A., Smith & Nephew plc, Kikkoman Biochemifa Company Ltd., Galderma S.A., Kewpie Corporation, Merz Pharma GmbH & Co. KGaA, Fidia Farmaceutici S.p.A., Anika Therapeutics Inc., Lifecore Biomedical Inc., Croma-Pharma GmbH, Contipro a.s., Seikagaku Corporation, HTL Biotechnology SAS, Altergon Italia S.r.l., and Bloomage Biotechnology Corporation Limited.

North America was the largest region in the hyaluronic acid market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in hyaluronic acid report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa. The countries covered in the hyaluronic acid market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report’s Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sudden escalation of U.S. tariffs and the consequent trade frictions in spring 2025 are severely impacting the pharmaceutical companies contend with tariffs on APIs, glass vials, and lab equipment inputs with few alternative sources. Generic drug makers, operating on razor-thin margins, are especially vulnerable, with some reducing production of low-profit medicines. Biotech firms face delays in clinical trials due to tariff-related shortages of specialized reagents. In response, the industry is expanding API production in India and Europe, increasing inventory stockpiles, and pushing for trade exemptions for essential medicines.

Hyaluronic acid is a naturally occurring compound in the human body, primarily found in the skin, connective tissues, and eyes. It acts as a lubricant and cushion in joints and tissues and plays a crucial role in retaining moisture. Due to its high water-binding capacity, it helps maintain skin hydration, plumpness, and elasticity. It is widely used in skincare products for moisturizing and anti-aging purposes, as well as in medical applications including joint injections for osteoarthritis, wound healing, and eye surgeries.

The primary types of products containing hyaluronic acid are multiple-injection doses and single-injection doses. Multiple-injection doses involve administering a medication through several injections over time to maintain effective therapeutic levels. These products include various grades, such as pharmaceutical-grade and cosmetic-grade hyaluronic acid, derived from sources including microbial fermentation, animal-based, and plant-based origins. Applications span active pharmaceutical ingredients, aesthetics, osteoarthritis treatment, cosmetics, ophthalmology, and dietary supplements. Key end-users include dermatology clinics, cosmetic surgery centers, medical spas, beauty centers, and related facilities.

The hyaluronic acid market research report is one of a series of new reports that provides hyaluronic acid market statistics, including hyaluronic acid industry global market size, regional shares, competitors with a hyaluronic acid market share, detailed hyaluronic acid market segments, market trends and opportunities, and any further data you may need to thrive in the hyaluronic acid industry. This hyaluronic acid market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The hyaluronic acid market consists of sales of hyaluronic acid serums, moisturizers, facial masks, dermal fillers, viscosupplements, burn and ulcer treatments, and eye drops. Values in this market are ‘factory gate’ values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values and are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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