Cleanroom Construction Global Market Report 2025

The cleanroom construction market size has grown rapidly in recent years. It will grow from $6.23 billion in 2024 to $6.94 billion in 2025 at a compound annual growth rate (CAGR) of 11.5%. The growth during the historical period can be attributed to the increasing demand for contamination-free environments, rising investments in high-precision manufacturing facilities, growing adoption of modular and prefabricated cleanroom designs, and the strengthening of regulatory compliance requirements across various industries.

The cleanroom construction market size is expected to see rapid growth in the next few years. It will grow to $10.59 billion in 2029 at a compound annual growth rate (CAGR) of 11.1%. The projected growth for the forecast period can be attributed to government-led initiatives supporting the pharmaceutical and electronics sectors, an increasing focus on sustainability and energy-efficient technologies, the rapid expansion of the biotechnology and semiconductor industries, rising research and development activities, and growing demand for biologics. Major trends expected during this period include the integration of modular construction techniques, technological advancements in cleanroom systems, the development of energy-efficient cleanroom designs, innovations in smart monitoring and control systems, and the increasing adoption of prefabricated panel solutions.

The expansion of the pharmaceutical and biotechnology sectors is expected to drive the growth of the cleanroom construction market in the coming years. The pharmaceutical and biotechnology sectors include industries engaged in researching, developing, and producing drugs, vaccines, and therapies to prevent or treat diseases using chemical and biological methods. These sectors have expanded due to rising investments in drug development and innovation, as companies increasingly focus on creating novel therapies to address unmet medical needs and emerging health challenges. Cleanroom construction supports the pharmaceutical and biotechnology sectors by providing controlled, contamination-free environments essential for sterile drug manufacturing, sensitive research processes, and compliance with strict regulatory standards. For example, in January 2025, according to the BioIndustry Association, a United Kingdom-based trade association, the UK biotech sector achieved significant growth in 2024, attracting 4.4 billion dollars (3.5 billion pounds) in investment, representing a 94 percent increase compared with the previous year. Therefore, the expansion of the pharmaceutical and biotechnology sectors is fueling the growth of the cleanroom construction market.

Key companies operating in the cleanroom construction market are focusing on developing advanced solutions such as modular wall systems to enhance flexibility, efficiency, and contamination control in controlled environments. Modular wall systems consist of prefabricated wall panels designed for cleanroom construction that enable quick installation, easy modification, and improved control over contamination, helping maintain sterile environments while reducing construction time and costs. For instance, in February 2025, Jansen Cleanrooms and Labs N.V., a Belgium-based construction company, introduced J’Clean, a new product line for cleanroom construction that includes modular wall systems, hinged door systems, interlock systems, lighting, and pass boxes. The product line is designed to meet stringent cleanliness, efficiency, and regulatory standards, serving industries such as pharmaceuticals, biotechnology, electronics, and healthcare. These modular solutions support faster installation, reduced downtime, and greater adaptability for facility expansion or upgrades. By combining reliability with modern design, the company aims to deliver complete cleanroom construction solutions that ensure optimal contamination control, energy efficiency, and long-term operational performance.

In September 2025, Equans U.S. Inc., a United States-based multi-technical services company, acquired AdvanceTEC LLC for an undisclosed amount. This acquisition aims to strengthen Equans U.S. Inc.’s cleanroom design and construction capabilities, particularly in modular and prefabricated solutions. It is expected to accelerate innovation, enhance project delivery speed and quality, and expand the company’s presence across regulated and precision-focused industries. AdvanceTEC LLC is a United States-based company specializing in cleanroom design and construction.

Major players in the cleanroom construction market are Grifols S.A., Lindner Group GmbH, Performance Contracting Group Inc., Advanced Technology Group Inc., Hodess Cleanroom Construction Inc., AES Clean Technology Inc., Terra Universal Inc., Allied Cleanrooms Ltd., Nicomac Srl, Angstrom Technology Inc., ACH Engineering Inc., American Cleanroom Systems Inc., Longden Company Inc., Clean Air Technology Inc., Nicos Group Inc., Total Clean Air Inc., PortaFab Corporation, Gerbig Engineering Company Inc., Clean Air Products Inc., and Cleanroom Construction Associates Inc.

North America was the largest region in the cleanroom construction market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in cleanroom construction report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report’s Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The rapid escalation of U.S. tariffs and the resulting trade tensions in spring 2025 are significantly impacting the construction sector, particularly in materials procurement and project costs. Higher duties on imported steel, aluminum, lumber, and machinery have driven up expenses for builders, contractors, and infrastructure developers, leading to increased project bids and delayed timelines. Construction equipment manufacturers face similar challenges, with tariffs on essential components and raw materials inflating production costs and squeezing margins. Additionally, retaliatory tariffs in international markets have curtailed exports of U.S.-made construction equipment and materials, further affecting profitability. The sector must now prioritize local sourcing, modular construction techniques, and supply chain diversification to control costs and ensure project viability amid ongoing trade uncertainties.

The cleanroom construction market research report is one of a series of new reports that provides cleanroom construction market statistics, including cleanroom construction industry global market size, regional shares, competitors with the cleanroom construction market share, cleanroom construction market segments, market trends, and opportunities, and any further data you may need to thrive in the cleanroom construction industry. This cleanroom construction market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

Cleanroom construction refers to the design and development of controlled environments in which air purity, temperature, humidity, and pressure are precisely managed to minimize contamination. This process involves the use of airtight finishes, non-shedding materials, and advanced filtration systems to maintain clean conditions. Proper airflow, temperature, and humidity control are ensured to support sensitive processes, making cleanrooms essential in environments where contamination could compromise product quality or research integrity.

The primary types of cleanroom construction include modular cleanrooms, stick-built cleanrooms, softwall cleanrooms, hardwall cleanrooms, and portable cleanrooms. A modular cleanroom is a fast, flexible, and reconfigurable controlled environment designed to maintain precise contamination, temperature, and pressure control. These cleanrooms are constructed using materials such as aluminum, steel, and glass, and are classified into cleanliness levels such as Class 10, Class 100, Class 1,000, Class 10,000, and Class 100,000. They are widely used across industries including pharmaceuticals, biotechnology, aerospace and defense, semiconductors, healthcare, and others.

The countries covered in the cleanroom construction market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The cleanroom construction market includes revenues earned by entities providing services such as cleanroom design, modular construction, heating, ventilation, and air conditioning (HVAC) system installation, contamination control integration, and project management and related validation, maintenance, and design consulting services. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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