+353-1-416-8900REST OF WORLD
+44-20-3973-8888REST OF WORLD
1-917-300-0470EAST COAST U.S
1-800-526-8630U.S. (TOLL FREE)
New

Protein Expression: Global Markets

  • PDF Icon

    Report

  • 157 Pages
  • November 2025
  • Region: Global
  • BCC Research
  • ID: 6191180
The global market for protein expression is estimated to grow from $4.7 billion in 2025 to reach $7.9 billion by 2030, at a compound annual growth rate (CAGR) of 10.9% from 2025 through 2030. The protein expression market is rapidly expanding due to investments in biotechnology research and the need for therapeutic proteins to treat chronic illnesses.

Report Scope

The report provides an overview of the global protein expression market and analyzes key market trends. Global revenue ($ million) for the base year 2024 and estimated data for the forecast period, 2025 through 2030, are also included. The market is segmented into expression system, product types, application, end user and regions. The regions covered in this study are North America, Europe, Asia-Pacific (APAC) and the Rest of the World (RoW), with a focus on major countries in these regions.

The report examines trends and challenges that affect the market and vendor landscape; analyzes environmental, social and corporate governance (ESG) developments; and discusses emerging technologies related to the market.

The report concludes with an analysis of the competitive landscape, providing rankings and market shares of key companies in the global protein expression market. A dedicated section of company profiles provides an overview, key financials, product portfolios and recent developments of leading companies, including a patent analysis.

The report includes:

  • 52 data tables and 65 additional tables
  • An overview of the global market for protein expression
  • In-depth analysis of global market trends, featuring historical revenue data for 2022-2024, estimated figures for 2025, as well as forecasts for 2030. This analysis includes projections of compound annual growth rates (CAGRs) through 2030
  • Evaluation of the current market size and revenue growth prospects specific to the protein expression, accompanied by a market share analysis by system type, product, application, end user and region
  • Analysis of current and future demand in the global protein expression, along with a detailed analysis of the competitive environment, market regulations and reimbursement practices
  • Analysis of drivers, challenges and opportunities affecting market growth
  • Coverage of evolving technologies, the current and future market potential, R&D activities, growth strategies, new product pipeline, regulatory framework and reimbursement scenarios, and ESG trends of the market
  • Market share analysis of the key market participants in the protein expression industry, along with their research priorities, product portfolios, global rankings and competitive landscape
  • Profiles of the major companies, including Thermo Fisher Scientific Inc., Bio-Rad Laboratories Inc., Merck KGaA, Sartorius AG and Agilent Technologies Inc.

Table of Contents

Chapter 1 Executive Summary
  • Market Outlook
  • Scope of Report
  • Market Summary
  • Market Growth Factors
  • Emerging Technologies
  • Segmental Analysis
  • Regional Analysis
  • Conclusion
Chapter 2 Market Overview
  • Technology Background
  • Protein Expression Workflow
  • Choice of Cell Type
  • Choice of Plasmid
  • Choice of Cell Expression System
  • Introduction to Protein Expression Systems
  • Protein Synthesis Machinery
  • Cloning Technologies
  • Constitutive and Inducible Promoters Commonly Used in Recombinant Protein Expression Systems
  • Production of Recombinant Proteins
  • Recombinant Protein Expression Methods
  • Comparison of Expression Systems
  • Post-Translational Processing
  • Problems Associated with the Production of Protein
  • Loss of Expression
  • Macroeconomic Factors Analysis
  • PESTEL Analysis
  • Impact of U.S. Tariff Laws on the Protein Expression Market
  • Porter's Five Forces Analysis
  • Bargaining Power of Buyers: Moderate
  • Bargaining Power of Suppliers: Moderate
  • Threat of Substitute Products: Low
  • Threat of New Entrants: Moderate
  • Industry Competition: High
Chapter 3 Market Dynamics
  • Overview
  • Market Drivers
  • Demand for Therapeutic Proteins and Biologics
  • Investments in Biopharmaceuticals
  • Technological Advances in Protein Expression Systems
  • Market Restraints
  • Complex Government Regulations and Policies
  • High Cost of Protein Drugs
  • Market Opportunities
  • Demand for Biopharmaceuticals in Emerging Countries
  • Expanded Applications for CRISPR Technology
Chapter 4 Regulatory Landscape
  • Overview
  • The U.S.
  • Europe
  • Asia-Pacific
  • Rest of the World
Chapter 5 Emerging Technologies and New Developments
  • Overview
  • CRISPR/Cas9 Genome Editing
  • Synthetic Biology
  • AI Integration in Protein Expression
Chapter 6 Market Segmentation Analysis
  • Segmentation Breakdown
  • Market Breakdown by System Type
  • Key Takeaways
  • Prokaryotic Expression Systems
  • Mammalian Cell Expression Systems
  • Yeast Expression Systems
  • Insect Cell Expression Systems
  • Cell-Free Expression Systems
  • Algal-based Expression Systems
  • Market Breakdown by Product Type
  • Key Takeaways
  • Reagents
  • Expression Vectors
  • Competent Cells
  • Instruments
  • Services
  • Market Breakdown by Application
  • Key Takeaways
  • Therapeutics
  • Industrial
  • Research
  • Market Breakdown by End User
  • Key Takeaways
  • Pharmaceutical and Biotechnology Companies
  • Contract Research Organizations
  • Academic Research Institutes
  • Others
  • Geographic Breakdown
  • Market Breakdown by Region
  • Key Takeaways
  • North America
  • Europe
  • Asia-Pacific
  • Rest of the World
Chapter 7 Competitive Intelligence
  • Key Takeaways
  • Top Companies' Ranking, 2024
  • Strategic Analysis
Chapter 8 Sustainability in the Protein Expression Market: ESG Perspective
  • Sustainability in the Protein Expression Market
  • Understanding ESG Data
  • ESG Performance Analysis
  • Environmental Performance
  • Social Performance
  • Governance Performance
  • Concluding Remarks
Chapter 9 Patent Landscape
  • Overview
  • Patents, by Year
  • Patents, by Leading Applicants
  • Patents, by Document Type
  • Recent Patents Relating to Protein Expression Technology
Chapter 10 Appendix
  • Methodology
  • References
  • Abbreviations
  • Company Profiles
  • AGILENT TECHNOLOGIES INC.
  • BIO-RAD LABORATORIES INC.
  • CORNING INC.
  • DANAHER CORP.
  • FUJIFILM CELLULAR DYNAMICS INC.
  • GENSCRIPT
  • LONZA
  • MERCK KGAA
  • NEW ENGLAND BIOLABS
  • ORIGENE TECHNOLOGIES INC.
  • PROMEGA CORP.
  • PROTEOGENIX INC.
  • QIAGEN
  • SARTORIUS AG
  • THERMO FISHER SCIENTIFIC INC.
List of Tables
Summary Table: Global Market for Protein Expression, by Region, Through 2030
Table 1: Advantages and Disadvantages of Protein Expression Systems
Table 2: Prokaryotes vs. Eukaryotes Protein Synthesis
Table 3: Comparison of Expression Systems
Table 4: Asia-Pacific Regulatory Landscape
Table 5: RoW Regulatory Landscape
Table 6: Comparison of Protein Expression Systems and Their Respective Advantages and Disadvantages
Table 7: Advantages, Challenges and Most Common Applications of Protein Expression Systems
Table 8: Global Market for Protein Expression, by Type, Through 2030
Table 9: Global Market for Prokaryotic Expression Systems, by Region, Through 2030
Table 10: Global Market for Mammalian Cell Expression Systems, by Region, Through 2030
Table 11: Global Market for Yeast Expression Systems, by Region, Through 2030
Table 12: Global Market for Insect Cell Expression Systems, by Region, Through 2030
Table 13: Global Market for Cell-Free Protein Expression Systems, by Region, Through 2030
Table 14: Global Market for Algal-based Expression Systems, by Region, Through 2030
Table 15: Global Market for Protein Expression, by Product, Through 2030
Table 16: Global Protein Expression Market for Reagents, by Region, Through 2030
Table 17: Characteristics of Commonly Used Expression Hosts
Table 18: Global Protein Expression Market for Expression Vectors, by Region, Through 2030
Table 19: Global Protein Expression Market for Competent Cells, by Region, Through 2030
Table 20: Global Protein Expression Market for Instruments, by Region, Through 2030
Table 21: Select Protein Expression Services
Table 22: Global Protein Expression Market for Services, by Region, Through 2030
Table 23: Global Market for Protein Expression, by Application, Through 2030
Table 24: Global Protein Expression Market for Therapeutics, by Region, Through 2030
Table 25: Global Protein Expression Market for Industrial Use, by Region, Through 2030
Table 26: Global Protein Expression Market for Research Use, by Region, Through 2030
Table 27: Global Market for Protein Expression, by End User, Through 2030
Table 28: Global Protein Expression Market for Pharmaceutical and Biotechnology Companies, by Region, Through 2030
Table 29: Global Protein Expression Market for Contract Research Organizations, by Region, Through 2030
Table 30: Global Protein Expression Market for Academic Research Organizations, by Region, Through 2030
Table 31: Global Protein Expression Market for Other End Users, by Region, Through 2030
Table 32: Global Market for Protein Expression, by Region, Through 2030
Table 33: North American Market for Protein Expression, by Type, Through 2030
Table 34: North American Market for Protein Expression, by Product, Through 2030
Table 35: North American Market for Protein Expression, by Application, Through 2030
Table 36: North American Market for Protein Expression, by End User, Through 2030
Table 37: North American Market for Protein Expression, by Country, Through 2030
Table 38: European-based Companies’ R&D Expenditures and Comparison of Their Net Sales, 2023
Table 39: European Market for Protein Expression, by Type, Through 2030
Table 40: European Market for Protein Expression, by Product, Through 2030
Table 41: European Market for Protein Expression, by Application, Through 2030
Table 42: European Market for Protein Expression, by End User, Through 2030
Table 43: European Market for Protein Expression, by Country, Through 2030
Table 44: Asia-Pacific Market for Protein Expression, by Type, Through 2030
Table 45: Asia-Pacific Market for Protein Expression, by Product, Through 2030
Table 46: Asia-Pacific Market for Protein Expression, by Application, Through 2030
Table 47: Asia-Pacific Market for Protein Expression, by End User, Through 2030
Table 48: Asia-Pacific Market for Protein Expression, by Country, Through 2030
Table 49: RoW Market for Protein Expression, by Type, Through 2030
Table 50: RoW Market for Protein Expression, by Product, Through 2030
Table 51: RoW Market for Protein Expression, by Application, Through 2030
Table 52: RoW Market for Protein Expression, by End User, Through 2030
Table 53: RoW Market for Protein Expression, by Subregion, Through 2030
Table 54: Top Companies’ Ranking, 2024
Table 55: Recent Developments in the Protein Expression Market, 2023-2025
Table 56: Key Focus Areas in ESG Metrics
Table 57: ESG Rankings for Major Protein Expression Companies, 2025*
Table 58: ESG: Environmental Overview
Table 59: ESG: Social Overview
Table 60: ESG: Governance Overview
Table 61: Patent Applications Related to Protein Expression, by Applicant, 2020-2025
Table 62: Protein Expression Technology Patents Filed, 2024
Table 63: Protein Expression Technology Patents Filed, 2025
Table 64: Abbreviations Used in the Protein Expression Market Report
Table 65: Agilent Technologies Inc.: Company Snapshot
Table 66: Agilent Technologies Inc.: Financial Performance, FY 2023 and 2024
Table 67: Agilent Technologies Inc.: Product Portfolio
Table 68: Agilent Technologies Inc.: News/Key Developments, 2024
Table 69: Bio-Rad Laboratories Inc.: Company Snapshot
Table 70: Bio-Rad Laboratories Inc.: Financial Performance, FY 2023 and 2024
Table 71: Bio-Rad Laboratories Inc.: Product Portfolio
Table 72: Bio-Rad Laboratories Inc.: News/Key Developments, 2025
Table 73: Corning Inc.: Company Snapshot
Table 74: Corning Inc.: Financial Performance, FY 2023 and 2024
Table 75: Corning Inc.: Product Portfolio
Table 76: Danaher Corp.: Company Snapshot
Table 77: Danaher Corp.: Financial Performance, FY 2023 and 2024
Table 78: Danaher Corp.: Product Portfolio
Table 79: Danaher Corp.: News/Key Developments, 2023-2025
Table 80: FUJIFILM Cellular Dynamics Inc.: Company Snapshot
Table 81: FUJIFILM Cellular Dynamics Inc.: Product Portfolio
Table 82: GenScript: Company Snapshot
Table 83: GenScript: Financial Performance, FY 2023 and 2024
Table 84: GenScript: Product Portfolio
Table 85: GenScript: News/Key Developments, 2024-2025
Table 86: Lonza: Company Snapshot
Table 87: Lonza: Financial Performance, FY 2023 and 2024
Table 88: Lonza: Product Portfolio
Table 89: Lonza: News/Key Developments, 2023-2025
Table 90: Merck KGaA: Company Snapshot
Table 91: Merck KGaA: Financial Performance, FY 2023 and 2024
Table 92: Merck KGaA: Product Portfolio
Table 93: Merck KGaA: News/Key Developments, 2023-2024
Table 94: New England Biolabs: Company Snapshot
Table 95: New England Biolabs: Product Portfolio
Table 96: New England Biolabs: News/Key Developments, 2025
Table 97: OriGene Technologies Inc.: Company Snapshot
Table 98: OriGene Technologies Inc.: Product Portfolio
Table 99: OriGene Technologies Inc.: News/Key Developments, 2025
Table 100: Promega Corp.: Company Snapshot
Table 101: Promega Corp.: Product Portfolio
Table 102: Promega Corp.: News/Key Developments, 2025
Table 103: ProteoGenix Inc.: Company Snapshot
Table 104: ProteoGenix Inc.: Product Portfolio
Table 105: Qiagen: Company Snapshot
Table 106: Qiagen: Financial Performance, FY 2023 and 2024
Table 107: Qiagen: Product Portfolio
Table 108: Qiagen: News/Key Developments, 2023
Table 109: Sartorius AG: Company Snapshot
Table 110: Sartorius AG: Financial Performance, FY 2023 and 2024
Table 111: Sartorius AG: Product Portfolio
Table 112: Sartorius AG: News/Key Developments, 2023-2025
Table 113: Thermo Fisher Scientific Inc.: Company Snapshot
Table 114: Thermo Fisher Scientific Inc.: Financial Performance, FY 2023 and 2024
Table 115: Thermo Fisher Scientific Inc.: Product Portfolio
Table 116: Thermo Fisher Scientific Inc.: News/Key Developments, 2025
List of Figures
Summary Figure: Global Market Shares of Protein Expression, by Region, 2024
Figure 1: Protein Expression Workflow
Figure 2: PESTEL Analysis: Protein Expression Market
Figure 3: Porter’s Five Forces Analysis: Protein Expression Market
Figure 4: Market Dynamics of Protein Expression
Figure 5: Venture Capital Averages for Biopharma Therapeutics and Platform Companies, 2010-2024
Figure 6: Technological Advances in Protein Expression Systems
Figure 7: Emerging Technologies in the Protein Expression Market
Figure 8: Global Market Shares of Protein Expression, by Type, 2024
Figure 9: Global Market Shares of Protein Expression, by Product, 2024
Figure 10: Global Market Shares of Protein Expression, by Application, 2024
Figure 11: Global Market Shares of Protein Expression, by End User, 2024
Figure 12: Global Market Shares of Protein Expression, by Region, 2024
Figure 13: North American Market Shares of Protein Expression, by Country, 2024
Figure 14: U.S. Elderly Population (65 and Older), Projection and Trends, 2010-2050
Figure 15: European Market Shares of Protein Expression, by Country, 2024
Figure 16: Asia-Pacific Market Shares of Protein Expression, by Country, 2024
Figure 17: RoW Market Shares of Protein Expression, by Subregion, 2024
Figure 18: How a Strong ESG Proposition Benefits Businesses
Figure 19: Patents Granted Related to Protein Expression Technology, by Year, 2020-2025
Figure 20: Patent Shares for Protein Expression Technology, by Document Type, 2020-2025
Figure 21: Agilent Technologies Inc.: Revenue Share, by Business Unit, FY 2024
Figure 22: Agilent Technologies Inc.: Revenue Share, by Country/Region, FY 2024
Figure 23: Bio-Rad Laboratories Inc.: Revenue Share, by Business Unit, FY 2024
Figure 24: Bio-Rad Laboratories Inc.: Revenue Share, by Country/Region, FY 2024
Figure 25: Corning Inc.: Revenue Share, by Business Unit, FY 2024
Figure 26: Corning Inc.: Revenue Share, by Country/Region, FY 2024
Figure 27: Danaher Corp.: Revenue Share, by Business Unit, FY 2024
Figure 28: Danaher Corp.: Revenue Share, by Country/Region, FY 2024
Figure 29: GenScript: Revenue Share, by Business Unit, FY 2024
Figure 30: GenScript: Revenue Share, by Country/Region, FY 2024
Figure 31: Lonza: Revenue Share, by Business Unit, FY 2024
Figure 32: Lonza: Revenue Share, by Country/Region, FY 2024
Figure 33: Merck KGaA: Revenue Share, by Business Unit, FY 2024
Figure 34: Merck KGaA: Revenue Share, by Country/Region, FY 2024
Figure 35: Qiagen: Revenue Share, by Business Unit, FY 2024
Figure 36: Qiagen: Revenue Share, by Country/Region, FY 2024
Figure 37: Sartorius AG: Revenue Share, by Business Unit, 2024
Figure 38: Sartorius AG: Revenue Share, by Country/Region, 2024
Figure 39: Thermo Fisher Scientific Inc.: Revenue Share, by Business Unit, FY 2024
Figure 40: Thermo Fisher Scientific Inc.: Revenue Share, by Country/Region, FY 2024

Companies Mentioned

  • Agilent Technologies Inc.
  • Bio-Rad Laboratories Inc.
  • Corning Inc.
  • Danaher Corp.
  • Fujifilm Cellular Dynamics Inc.
  • Genscript
  • Lonza
  • Merck KGaA
  • New England Biolabs
  • Origene Technologies Inc.
  • Promega Corp.
  • Proteogenix Inc.
  • Qiagen
  • Sartorius AG
  • Thermo Fisher Scientific Inc.

Table Information