The U.S. leukemia therapeutics market size was estimated at USD 7.23 billion in 2024 and is projected to reach USD 13.07 billion by 2033, growing at a CAGR of 6.80% from 2025 to 2033. The industry is expanding due to the strong adoption of targeted therapies that offer high clinical precision.
Increased use of genomic profiling supports accurate treatment selection and enhances overall therapeutic outcomes. Growth in CAR-T cell therapy utilization adds momentum through improved remission durability in high-risk patients. Advancements in bispecific antibodies strengthen options for relapsed and refractory cases. For instance, in March 2024, the National Cancer Institute (via the Surveillance, Epidemiology, and End Results Program) reported that in the U.S., there were an estimated 536,245 people living with leukemia in 2022, representing the prevalence of the disease. The broader integration of molecular diagnostics enhances patient identification for advanced therapies. Continuous development of next-generation agents sustains momentum in the market. The rising preference for personalized oncology care is expected to strengthen long-term treatment demand.
Therapeutic innovation strengthens market growth as clinical pipelines deliver novel mechanisms for acute and chronic leukemia. Wider availability of oral targeted agents improves adherence and supports strong commercial performance. Expansion of clinical evidence enhances prescriber confidence across major oncology networks. Increased survival rates create ongoing demand for maintenance and follow-up therapies. High disease burden within aging populations drives treatment initiation across multiple leukemia types. Advancements in combination regimens have improved the depth of response in both frontline and salvage settings. For instance, in November 2025, Business Wire reported that the U.S. Food and Drug Administration (FDA) granted Orphan Drug Designation to Leukogene Therapeutics Inc.’s lead product candidate LTI-214 (also named M2T-CD33) for the treatment of Acute Myeloid Leukemia (AML), providing incentives such as tax credits on qualified clinical trial costs, waiver of certain FDA fees, and U.S. market exclusivity upon approval. Strong investment from major pharmaceutical companies accelerates the development and commercialization of new agents.
Improved treatment access through specialized oncology centers contributes to market expansion across the U.S. Growth in real-world evidence supports broader adoption of immunotherapy and targeted strategies. Higher utilization of high-value biologics strengthens revenue contribution across leading manufacturers. Enhanced therapeutic durability reduces the frequency of relapse and encourages continued long-term therapy. Rising clinical trial activity in major cancer institutions supports rapid evaluation of emerging platforms. An increased emphasis on precision treatment pathways supports the consistent uptake of advanced therapeutics. Continuous improvements in patient management practices reinforce sustained demand for leukemia treatments.
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Increased use of genomic profiling supports accurate treatment selection and enhances overall therapeutic outcomes. Growth in CAR-T cell therapy utilization adds momentum through improved remission durability in high-risk patients. Advancements in bispecific antibodies strengthen options for relapsed and refractory cases. For instance, in March 2024, the National Cancer Institute (via the Surveillance, Epidemiology, and End Results Program) reported that in the U.S., there were an estimated 536,245 people living with leukemia in 2022, representing the prevalence of the disease. The broader integration of molecular diagnostics enhances patient identification for advanced therapies. Continuous development of next-generation agents sustains momentum in the market. The rising preference for personalized oncology care is expected to strengthen long-term treatment demand.
Therapeutic innovation strengthens market growth as clinical pipelines deliver novel mechanisms for acute and chronic leukemia. Wider availability of oral targeted agents improves adherence and supports strong commercial performance. Expansion of clinical evidence enhances prescriber confidence across major oncology networks. Increased survival rates create ongoing demand for maintenance and follow-up therapies. High disease burden within aging populations drives treatment initiation across multiple leukemia types. Advancements in combination regimens have improved the depth of response in both frontline and salvage settings. For instance, in November 2025, Business Wire reported that the U.S. Food and Drug Administration (FDA) granted Orphan Drug Designation to Leukogene Therapeutics Inc.’s lead product candidate LTI-214 (also named M2T-CD33) for the treatment of Acute Myeloid Leukemia (AML), providing incentives such as tax credits on qualified clinical trial costs, waiver of certain FDA fees, and U.S. market exclusivity upon approval. Strong investment from major pharmaceutical companies accelerates the development and commercialization of new agents.
Improved treatment access through specialized oncology centers contributes to market expansion across the U.S. Growth in real-world evidence supports broader adoption of immunotherapy and targeted strategies. Higher utilization of high-value biologics strengthens revenue contribution across leading manufacturers. Enhanced therapeutic durability reduces the frequency of relapse and encourages continued long-term therapy. Rising clinical trial activity in major cancer institutions supports rapid evaluation of emerging platforms. An increased emphasis on precision treatment pathways supports the consistent uptake of advanced therapeutics. Continuous improvements in patient management practices reinforce sustained demand for leukemia treatments.
U.S. Leukemia Therapeutics Market Report Segmentation
This report forecasts revenue growth at country level and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, the analyst has segmented the U.S. leukemia therapeutics market report based on type, treatment, and distribution channels:Type Outlook (Revenue, USD Million, 2021-2033)
- Chronic Myeloid Leukemia (CML)
- Chronic Lymphocytic Leukemia (CLL)
- Acute Lymphocytic Leukemia (ALL)
- Acute Myeloid Leukemia (AML)
- Others
Treatment Outlook (Revenue, USD Million, 2021-2033)
- Chemotherapy
- Targeted Therapy
- Immunotherapy
- Others
Distribution Channels Outlook (Revenue, USD Million, 2021-2033)
- Hospital Pharmacy
- Retail Pharmacy
- Others
Why should you buy this report?
- Comprehensive Market Analysis: Gain detailed insights into the market across major regions and segments.
- Competitive Landscape: Explore the market presence of key players.
- Future Trends: Discover the pivotal trends and drivers shaping the future of the market.
- Actionable Recommendations: Utilize insights to uncover new revenue streams and guide strategic business decisions.
This report addresses:
- Market intelligence to enable effective decision-making
- Market estimates and forecasts from 2018 to 2030
- Growth opportunities and trend analyses
- Segment and regional revenue forecasts for market assessment
- Competition strategy and market share analysis
- Product innovation listings for you to stay ahead of the curve
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Table of Contents
Chapter 1. Methodology and Scope
Chapter 2. Executive Summary
Chapter 3. U.S. Leukemia Therapeutics Market Variables, Trends, & Scope
Chapter 4. U.S. Leukemia Therapeutics Market: Type Business Analysis
Chapter 5. U.S. Leukemia Therapeutics Market: Treatment Business Analysis
Chapter 6. U.S. Leukemia Therapeutics Market: Distribution Channels Business Analysis
Chapter 7. Competitive Landscape
List of Tables
List of Figures
Companies Mentioned
The key companies profiled in this U.S. Leukemia Therapeutics market report include:- Novartis
- Roche / Genentech
- AbbVie
- Bristol-Myers Squibb (BMS)
- Pfizer
- Amgen
- Johnson & Johnson (Janssen)
- Gilead Sciences (Kite Pharma)
- AstraZeneca
- Sanofi
Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 150 |
| Published | November 2025 |
| Forecast Period | 2024 - 2033 |
| Estimated Market Value ( USD | $ 7.23 Billion |
| Forecasted Market Value ( USD | $ 13.07 Billion |
| Compound Annual Growth Rate | 6.8% |
| Regions Covered | United States |
| No. of Companies Mentioned | 11 |
