Regenerative Dentistry Global Market Report 2025

The regenerative dentistry market size has grown rapidly in recent years. It will grow from $2.45 billion in 2024 to $2.7 billion in 2025 at a compound annual growth rate (CAGR) of 10%. The growth in the historic period can be linked to the increasing prevalence of dental diseases, rising awareness of oral health, growing demand for cosmetic dentistry, an expanding geriatric population, and broader dental insurance coverage.

The regenerative dentistry market size is expected to see strong growth in the next few years. It will grow to $3.91 billion in 2029 at a compound annual growth rate (CAGR) of 9.7%. The growth in the forecast period can be driven by rising demand for tissue engineering solutions, greater availability of stem-cell-based treatments, the expansion of dental clinics offering regenerative procedures, increasing government support and funding, and a growing patient preference for natural tooth restoration. Major trends in the forecast period include technological advancements in biomaterials, progress in stem cell applications, innovations in 3D bioprinting of dental tissues, ongoing research and development in growth factors, and increased investment in personalized dental regeneration.

The rising prevalence of periodontal diseases is expected to play a significant role in the growth of the regenerative dentistry market in the coming years. Periodontal diseases are inflammatory conditions that affect the tissues supporting the teeth, such as the gums, periodontal ligament, and alveolar bone. These diseases can cause symptoms like swollen gums, bleeding, and, in severe cases, tooth loss. The increasing prevalence of periodontal diseases is largely driven by poor oral hygiene, which leads to plaque buildup and gum infections. Regenerative dentistry is crucial in addressing this issue by repairing damaged gum and bone tissues using advanced biomaterials and emerging stem cell-based therapies. For example, according to Mint Dental Centre, a UK-based dental provider, the proportion of the UK population affected by gum disease is expected to increase from 42% in 2025 to 54% by 2050, reflecting a significant upward trend. Therefore, the growing prevalence of periodontal diseases is projected to drive the expansion of the regenerative dentistry market.

Key players in the regenerative dentistry market are focusing on advancements in restorative regenerative dental techniques, such as the development of allograft bone in a syringe, to improve bone grafting efficiency, enhance clinical outcomes, and simplify surgical procedures for dental professionals. Allograft bone in a syringe is a ready-to-use bone graft material derived from donor (human) bone tissue that has been processed, sterilized, and packaged in a pre-filled syringe, ensuring convenience and precision during dental procedures. For instance, in July 2024, TBS Dental LLC, a US-based dental solutions company, launched the REGEN line, which includes regenerative dental products such as bone particulate in a curved-syringe applicator, a jar-format mineralized cortico-cancellous graft, and a resorbable collagen membrane with high tensile strength and excellent contouring ability for socket preservation and soft-tissue regeneration.

In June 2023, Solmetex LLC, a US-based provider of dental amalgam separators and environmental compliance solutions, acquired Impladent Ltd. for an undisclosed amount. This acquisition allows Solmetex LLC to expand its global presence and enhance its portfolio of dental waste management products. Impladent Ltd. is a US-based company that offers precision dental instruments and implantology solutions for dental practices.

Major companies operating in the regenerative dentistry market are Evonik Industries AG, Henry Schein Inc., Dentsply Sirona Inc, Institut Straumann AG, Integra LifeSciences, Sunstar Suisse S.A., LifeNet Health Inc., Advanced Medical Solutions Group plc, Geistlich Pharma AG, Ziacom Group, Septodont Holding, BEGO Medical GmbH & Co. KG, Meisinger GmbH & Co. KG, SigmaGraft Biomaterials, Regedent AG, Bioimplon GmbH, B&B Dental Implant Company, Dentium Co. Ltd., MegaGen Implant Co. Ltd., Meccellis Biotechnologies SAS

North America was the largest region in the regenerative dentistry market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in regenerative dentistry report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa. The countries covered in the regenerative dentistry market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report’s Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sudden escalation of U.S. tariffs and the consequent trade frictions in spring 2025 are severely impacting the healthcare sector, particularly in the supply of critical medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are facing higher costs for imported surgical instruments, imaging equipment, and consumables such as syringes and catheters, many of which have limited domestic alternatives. These increased costs are straining healthcare budgets, leading some providers to delay equipment upgrades or pass on expenses to patients. Additionally, tariffs on raw materials and components are disrupting the production of essential drugs and devices, causing supply chain bottlenecks. In response, the industry is diversifying sourcing strategies, boosting local manufacturing where possible, and advocating for tariff exemptions on life-saving medical products.

The regenerative dentistry market research report is one of a series of new reports that provides regenerative dentistry market statistics, including regenerative dentistry industry global market size, regional shares, competitors with a regenerative dentistry market share, detailed regenerative dentistry market segments, market trends and opportunities, and any further data you may need to thrive in the regenerative dentistry industry. This regenerative dentistry market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

Regenerative dentistry is a branch of dental science dedicated to restoring damaged or lost oral tissues - such as teeth, bone, and gums - using biological and tissue engineering approaches. It incorporates stem cells, biomaterials, and growth factors to activate the body’s natural healing mechanisms. The primary goal of regenerative dentistry is to regrow functional dental tissues rather than replace them with artificial materials, with applications including pulp and periodontal regeneration, bone reconstruction, and potential development of bioengineered teeth.

The key types of regenerative dentistry materials include natural and synthetic options. Natural materials refer to biologically sourced regenerative dental components such as autografts, allografts, xenografts, collagen membranes, and platelet-rich derivatives that aid the body’s natural healing and tissue formation processes. The tissues involved include hard and soft tissue reconstruction, applied through technologies such as tissue engineering, stem cell therapy, and others. These materials are used in various applications such as periodontal regeneration, endodontic regeneration, tooth reconstruction, bone regeneration, and additional procedures, and are utilized across hospitals, dental clinics, and other end-user settings.

The regenerative dentistry market includes revenues earned by entities by providing services such as periodontal tissue regeneration, pulp-dentin regeneration, alveolar bone grafting and ridge augmentation, guided tissue regeneration (GTR), and platelet-rich fibrin (PRF) or platelet-rich plasma (PRP) procedures. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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