Nucleotides Supplements Global Market Report 2025

The nucleotide supplements market size has grown rapidly in recent years. It will grow from $2.49 billion in 2024 to $2.78 billion in 2025 at a compound annual growth rate (CAGR) of 11.6%. The growth in the historic period can be linked to growing consumer awareness about immune and cellular health, increasing demand for functional foods and dietary supplements, rising prevalence of chronic diseases, expansion of infant nutrition and pediatric health products, and increasing adoption of personalized nutrition solutions.

The nucleotide supplements market size is expected to see rapid growth in the next few years. It will grow to $4.27 billion in 2029 at a compound annual growth rate (CAGR) of 11.3%. The growth in the forecast period can be driven by increasing investment in the nutraceutical and pharmaceutical sectors, growing demand for nucleotide-enriched functional foods, rising awareness about nucleotide benefits in sports and wellness, expansion of global distribution channels including online platforms, and increasing research on nucleotide applications in human and animal health. Major trends in the forecast period include advancements in nucleotide formulation and delivery, innovations in bioactive nucleotide supplements, developments in infant and pediatric formula enrichment, research and developments in nucleotide-based therapeutics, and advancements in high-bioavailability and stabilized nucleotide products.

The rising demand for dietary supplements is expected to drive the growth of the nucleotide supplements market in the coming years. Dietary supplements include a wide variety of products such as vitamins, minerals, amino acids, and other nutrients designed to complement the diet and support overall health. This demand is increasing as health awareness among consumers grows, leading to a greater emphasis on preventive healthcare and wellness. Nucleotide supplements, a specific category of dietary supplement, are used to support cellular repair, immune function, and metabolic health. For example, in September 2025, the Australian Bureau of Statistics reported that in 2023, approximately one in three individuals (33.6%) used dietary supplements, with a notably higher usage rate among adult females (43.7%) compared to adult males (30.8%). Therefore, the growing interest in dietary supplements is contributing to the expansion of the nucleotide supplements market.

Companies operating in the nucleotide supplements market are focusing on expanding their product portfolios with advanced, research-backed formulations that enhance immune function, growth, and overall health in animals. For example, in October 2025, Bioiberica, a Spain-based pharmaceutical company, expanded its Nucleoforce line with three new nucleotide-based ingredients: Nucleoforce Immunity, Nucleoforce Performance, and Nucleoforce High Flowability (HF). These ingredients are designed to support immune health, growth, and production efficiency in pets, livestock, and aquaculture species. Derived naturally from yeast, these nucleotide concentrates help animals during periods of stress, rapid development, or poor nutrition. Early research suggests that Nucleoforce can improve growth and disease resistance, especially when combined with bioactive compounds such as seaweed meal and olive extract.

In July 2025, Sudeep Pharma Limited, an India-based manufacturer of pharmaceutical and food-grade mineral ingredients, acquired Nutrition Supplies Services (NSS) for an undisclosed amount. Through this acquisition, Sudeep Pharma aims to expand its global presence in the infant formula and clinical nutrition sectors by integrating advanced micronutrient and nucleotide premix capabilities into its specialty ingredient portfolio. NSS, an Ireland-based company, specializes in advanced micronutrient premixes, including blends of amino acids and nucleotides, primarily for infant and clinical nutrition.

Major companies operating in the nucleotides supplements market are Cargill Incorporated, BASF SE, Merck KGaA, Thermo Fisher Scientific Inc., Evonik Industries AG, Lallemand Inc., Integrated DNA Technologies Inc., Promega Corporation, Takara Bio Inc., GenScript Biotech Corporation, Bioiberica S.A.U., Bluebonnet Nutrition Corporation, Elysium Health Inc., Ajinomoto Health & Nutrition North America Inc., InVite Health Inc., Leiber GmbH, TriLink BioTechnologies LLC, Bio Basic Inc., Creative Biogene Inc., Jena Bioscience GmbH, GeneCopoeia Inc., Quantum Nutrition Labs LLC, GMPriority Pharma Inc.

North America was the largest region in the nucleotide supplements market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in nucleotide supplements report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa. The countries covered in the nucleotide supplements market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report’s Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sudden escalation of U.S. tariffs and the consequent trade frictions in spring 2025 are severely impacting the pharmaceutical companies contend with tariffs on APIs, glass vials, and lab equipment inputs with few alternative sources. Generic drug makers, operating on razor-thin margins, are especially vulnerable, with some reducing production of low-profit medicines. Biotech firms face delays in clinical trials due to tariff-related shortages of specialized reagents. In response, the industry is expanding API production in India and Europe, increasing inventory stockpiles, and pushing for trade exemptions for essential medicines.

The nucleotides supplements market research report is one of a series of new reports that provides nucleotides supplements market statistics, including the nucleotides supplements industry global market size, regional shares, competitors with the nucleotides supplements market share, detailed nucleotides supplements market segments, market trends, and opportunities, and any further data you may need to thrive in the nucleotides supplements industry. This nucleotides supplements market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

Nucleotide supplements are bioactive nutritional compounds that provide purified nucleotide molecules composed of a nitrogenous base, a sugar, and phosphate groups essential for DNA, RNA, and energy metabolism in cells. They are designed to support cellular repair, immune health, and metabolic efficiency by supplying exogenous nucleotides during conditions where internal synthesis is insufficient.

The key product types in nucleotide supplements are DNA nucleotides, RNA nucleotides, and others. DNA nucleotides are the molecular building blocks of deoxyribonucleic acid, carrying hereditary information and ensuring the accurate transfer of genetic material during cell division and reproduction. They consist of nitrogenous bases, including pyrimidines and purines. These supplements are distributed through channels such as online stores, supermarkets or hypermarkets, specialty stores, and others. Their applications span pharmaceuticals, food, animal feed additives, and drug discovery, serving end-users across the health and wellness sector, pharmaceutical industry, nutraceutical companies, and the food and beverage industry.

The nucleotide supplements market consists of sales of purified nucleotide ingredients and formulated nucleotide supplement products such as powders, capsules, premixes, DNA nucleotides, and RNA nucleotides. Values in this market are ‘factory gate’ values; that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

This product will be delivered within 3-5 business days.