The single cell sequencing market is estimated to grow from USD 1.38 billion in the current year and is anticipated to grow at a CAGR of 15% during the forecast period, till 2035.
Single cell technologies provide numerous benefits compared to conventional genomic analyses, allowing for the identification of intricate and infrequent cell populations, while clarifying developmental pathways of unique cell lineages. Although single cell technologies have the potential for various applications in biotechnology and medical research, they remain confined to preliminary research endeavors. This is mainly due to specific difficulties linked to data processing and quality management. Additionally, the absence of flexibility in silico tools is viewed as one of the key obstacles to effective analysis and interpretation of single cell sequencing data. Moreover, the steady expenses of process execution and related labor-intensive protocols present additional obstacles to embracing single cell sequencing technology. The launch of the RNA-QC-Chain tool (aimed at tackling issues related to data processing and quality control) and the Human Cell Atlas initiative (which focuses on creating the first entire transcriptome map of human cells) are viewed as significant milestones in single cell genomics. Considering the capability of single cell RNA sequencing (scRNA-seq) technologies to explore previously unclear cellular processes and discover new biomarkers / therapeutic targets, they are expected to experience considerable market growth and acceptance in biomedical research throughout the forecast period.
SINGLE CELL SEQUENCING SERVICES AND TECHNOLOGIES MARKET: OVERVIEW
The market sizing and opportunity analysis has been segmented across the following parameters:
Market Segment
- Services
- Technologies
Type of System
- Sequencing
- Workflow Instruments
End-user
- Academics and Research Institutes
- Pharmaceutical Companies
- Other End-users
Area of Application
- Diagnostics
- Drug Discovery
- Precision Medicine
Key Geographies
- North America
- Europe
- Asia-Pacific
- Rest of the World
SINGLE CELL SEQUENCING MARKET: GROWTH AND TRENDS
Over the years, advancements in technology within genomics have allowed pharmaceutical companies to pursue a more individualized and focused method for developing drugs and therapies. In particular, next-generation sequencing (NGS) technologies have made it possible to sequence millions of human genomes from various backgrounds. The significant amount of blockchain in genomic data management from the previously mentioned sequencing studies have produced important insights into individuals' probable reactions to various treatment protocols. Advancements in this area have made NGS technologies more cost-effective and widely available. The price of sequencing one genome has decreased from approximately USD 3 billion (Human Genome Project 1990) to USD 1,000 (Illumina sequencing kits) in the past twenty years. Nonetheless, NGS-based analyses are restricted to providing adequate information on gene expression. This method cannot quantify nucleic acid content within individual cells, thus failing to provide gene expression data at single cell resolution. Enhanced molecular probing solutions are needed to gain a deeper insight into how individual cells interact with their microenvironment. In this setting, high-throughput single cell analysis, a novel analytical method, is regarded as an effective approach for examining individual cells, allowing scientists to investigate gene expression at the resolution of single cells.Single cell technologies provide numerous benefits compared to conventional genomic analyses, allowing for the identification of intricate and infrequent cell populations, while clarifying developmental pathways of unique cell lineages. Although single cell technologies have the potential for various applications in biotechnology and medical research, they remain confined to preliminary research endeavors. This is mainly due to specific difficulties linked to data processing and quality management. Additionally, the absence of flexibility in silico tools is viewed as one of the key obstacles to effective analysis and interpretation of single cell sequencing data. Moreover, the steady expenses of process execution and related labor-intensive protocols present additional obstacles to embracing single cell sequencing technology. The launch of the RNA-QC-Chain tool (aimed at tackling issues related to data processing and quality control) and the Human Cell Atlas initiative (which focuses on creating the first entire transcriptome map of human cells) are viewed as significant milestones in single cell genomics. Considering the capability of single cell RNA sequencing (scRNA-seq) technologies to explore previously unclear cellular processes and discover new biomarkers / therapeutic targets, they are expected to experience considerable market growth and acceptance in biomedical research throughout the forecast period.
SINGLE CELL SEQUENCING SERVICES AND TECHNOLOGIES MARKET: KEY INSIGHTS
The report delves into the current state of the single cell sequencing services and technologies market and identifies potential growth opportunities within industry. Some key findings from the report include:- Presently, close to 100 players claim to offer single cell sequencing services using a variety of unique technology platforms across the globe.
- The current market landscape is characterized by the presence of several non-industry players based in developed regions; quite recently, some industry players have entered this upcoming segment of the industry.
- Technology providers are steadily enhancing their respective product portfolios in order to achieve a competitive edge in the industry.
- Over the years, the intellectual capital related to single cell sequencing systems has grown at a commendable pace; majority of the patents have been filed in North America.
- Several organizations, having realized the untapped potential within this emerging segment, have awarded grants worth ~USD 1 billion, across 2,300+ instances in the period since 2016.
- The growing interest is also reflected by the surge of activity witnessed in this field, in form of capital investments, partnership agreements and product launches.
- Given the rising demand for single cell genomic data, and anticipated introduction of advanced sequencing technologies, the market is poised to grow at an annualized rate of ~17% over the next decade.
- The projected opportunity within the single cell sequencing market is expected to be well distributed within different areas of application and end users, across the globe.
SINGLE CELL SEQUENCING MARKET: KEY SEGMENTS
Sequencing Systems are Likely to Capture Majority of the Current Single-cell Sequencing Market Share
In terms of type of instrument, the single-cell sequencing market is segmented across various instruments such as workflow and sequencing instruments. In the current year, majority of the market share is captured by sequencing instruments (around 51%). However, the workflow segment is likely to grow at a higher CAGR of 34% during the forecast period.Currently, Academic and Research Institutions Capture the Highest Singe Cell Sequencing Market Share
In terms of end-users, the single-cell sequencing market is segmented across academic and research institutions, pharmaceutical companies and other end-users. Most of the current market share is captured by academic and research institutions (around 60%), followed by pharmaceutical companies (30%). The trend is likely to similar in the coming years.At present, Academic and Research Institutions Capture the Highest Single Cell Sequencing Market Share
In terms of end-users, the single-cell sequencing market is segmented across academic and research institutions, pharmaceutical companies and other end-users. Most of the current market share is captured by academic and research institutions (around 60%), followed by pharmaceutical companies (30%). The trend is likely to similar in the coming years.Drug Discovery Segment is Likely to Capture the Highest Singe Cell Sequencing Market Share in the Future
In terms of area of application, the single-cell sequencing market is segmented across drug discovery, diagnostics, precision medicine and others. Around 50% of the market share is likely to be captured by drug discovery segment, followed by diagnostics (20%) and precision medicine (17%).North America is Likely to Propel the Single-cell Sequencing Market
In terms of geographical regions, the single-cell sequencing market is segmented across North America, Europe, Asia-Pacific and Rest of the World. Around 50% of the market share is likely to be captured by North America, followed by Europe (26%) and Asia-Pacific (24%).Example Players in Single cell Sequencing Market
- Active Motif
- Admera Health
- Annoroad Genomics
- BGI Genomics
- CD Genomics
- MedGenome
- Quick Biology
- SingulOmics
- 10x Genomics
- Cell Microsystems
- Fluidigm
- Illumina
- Mission Bio
- Oxford Nanopore Technologies
SINGLE CELL SERVICES AND TECHNOLOGIES MARKET: RESEARCH COVERAGE
- Market Sizing and Opportunity Analysis: The report features an in-depth analysis of the single cell sequencing market, focusing on key market segments, including [A] market segments, [B] type of system, [C] end-user, [D] area of application, and [E] key geographical regions.
- Market Landscape: A detailed assessment of overall competitive landscape of single cell sequencing workflow instruments based on several relevant parameters, such as [A] target nucleic acid, [B] type of application, [C] type of application, [D] year of establishment, [E] company size and [F] geographical location.
- Company Competitiveness Analysis: A comprehensive competitive analysis of single cell technologies examining factors, such as supplier power and other important technology related specifications, such as maximum sequencing output, maximum reads per run, maximum read length, quality score, applications and cost of sequencer.
- Company Profiles: In-depth profiles of single cell companies that are engaged in offering single cell sequencing services and single cell technologies, based on several parameters such as [A] year of establishment, [B] location of headquarters, [C] proprietary technology platforms, [D] recent developments and [E] an informed future outlook.
- Patent Analysis: An insightful analysis of the various patents that have been filed / granted for single cell sequencing technologies, based on parameters, such as [A] patent type, [B] publication year, [C] geographical location, [D] Cooperative Patent Classification (CPC) symbols, [E] emerging focus areas, and [F] type of applicant.
- Grants Analysis: A detailed analysis of the grants that have been awarded to research institutes engaged in projects related to single cell sequencing, based on multiple parameters, such as [A] year of grant award, [B] grant amount, [C] focus area, [D] activity code, [E] support period, [F] funding mechanism, [G] funding institute center, [H] type of recipient organization, [I] popular recipient organizations and [J] prominent program officers.
- Recent Developments: An insightful analysis of the recent developments / trends in the related to single cell sequencing, offering insights on [A] partnerships and collaborations established within the industry, [B] funding and investments, and [C] recent product launches related to single cell sequencing.
KEY QUESTIONS ANSWERED IN THIS REPORT
- How many companies are currently engaged in this market?
- Which are the leading companies in this market?
- What is the current global capacity of developers?
- What factors are likely to influence the evolution of this market?
- What is the current and future market size?
- What is the CAGR of this market?
- How is the current and future market opportunity likely to be distributed across key market segments?
REASONS TO BUY THIS REPORT
- The report provides a comprehensive market analysis, offering detailed revenue projections of the overall market and its specific sub-segments. This information is valuable to both established market leaders and emerging entrants.
- Stakeholders can leverage the report to gain a deeper understanding of the competitive dynamics within the market. By analyzing the competitive landscape, businesses can make informed decisions to optimize their market positioning and develop effective go-to-market strategies.
- The report offers stakeholders a comprehensive overview of the market, including key drivers, barriers, opportunities, and challenges. This information empowers stakeholders to stay abreast of market trends and make data-driven decisions to capitalize on growth prospects.
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Table of Contents
1. PREFACE
3. INTRODUCTION
4. MARKET LANDSCAPE: SINGLE CELL SEQUENCING SERVICE PROVIDERS
5. MARKET LANDSCAPE: SINGLE CELL SEQUENCING TECHNOLOGY PROVIDERS
6. SINGLE CELL SEQUENCING TECHNOLOGIES: COMPETITIVENESS ANALYSIS
7. COMPANY PROFILES: SINGLE CELL SEQUENCING SERVICE PROVIDERS
8. COMPANY PROFILES: SINGLE CELL SEQUENCING TECHNOLOGY PROVIDERS
9. PATENT ANALYSIS
10. ACADEMIC GRANT ANALYSIS
11. RECENT DEVELOPMENTS: SINGLE CELL SEQUENCING MARKET
12. MARKET SIZING AND OPPORTUNITY ANALYSIS
13. CONCLUSION
LIST OF FIGURES
LIST OF TABLES
Companies Mentioned (Partial List)
A selection of companies mentioned in this report includes, but is not limited to:
- 10x Genomics
- 1CellBio
- Active Motif
- Admera Health
- Aelian Biotechnology
- Agency for Science Technology and Research
- Agilent Technologies
- Albert Einstein College of Medicine
- Annoroad Gene Technology
- Australian Genome Research Facility
- Becton Dickinson
- BGI Genomics
- Bigelow Single Cell Genomics Centre
- Bioinformatics and Expression Analysis Core Facility (Karolinska Institutet)
- BioLegend
- Immudex
- Biomedical Research Core Facilities (University of Michigan Medical School)
- Biopolymers Facility (Harvard Medical School)
- Bio-Rad Laboratories
- Biotech Research and Innovation Centre (University of Copenhagen)
- Biotechnology Center (University of Wisconsin-Madison)
- Broad Institute
- Bucher Biotec
- California Institute of Technology
- Cancer Genomics Center (University of Texas)
- Cancer Research UK Cambridge Institute (University of Cambridge)
- CARTANA
- CD Genomics
- Cedars-Sinai Genomics Core
- Cell Biologics
- Cell Microsystems
- Cellarity
- CellChorus
- Celldom
- CellTool
- Cellular Research
- Celsee
- Celsius Therapeutics
- Center for Gastrointestinal Biology and Disease (University of North Carolina School of Medicine)
- Center for Genetic Medicine (Northwestern University)
- Center for Translational Genomics (Lund University)
- Centre for Genome-Enabled Biology and Medicine (University of Aberdeen)
- Centre for Health Genomics and Informatics (University of Calgary)
- Centro Nacional de Análisis Genómico
- Clearbridge BioMedics
- Cleveland Clinic
- Cold Spring Harbor Laboratory
- Columbia Genome Center (Columbia University)
- Core Facility Genomics (Amsterdam UMC)
- Core Immunology Lab (University of California)
- Covance
- Cytena
- Cytomos
- Cytosurge
- DNA Core Facility (University of Missouri)
- DNA Technologies Core (University of California Davis)
- Dolomite Bio
- Droplet Genomics
- Duke Molecular Physiology Institute
- Earlham Institute
- Eldan
- Enigma Life Sciences
- Epigenomics and DNA Sequencing Core Facility (NIH)
- Epinomics
- Exosomeplus
- FlowJo
- Fluidigm
- Fulgent Genetics
- Functional Genomics Center Zurich (University of Zurich)
- GenapSys
- Genentech
- Genetic Resources Core Facility (Johns Hopkins University)
- GENEWIZ
- Genome Quebec
- Genome Sequencing Service Center (Stanford University)
- Genome Technology Access Center (Washington University)
- GenomeScan
- Genomics Core Facility (European Molecular Biology Laboratory)
- Genomics Core Facility (Lewis-Sigler Institute for Integrative Genomics)
- Genomics Facility (University of Chicago)
- Genuity Science
- Gladstone Genomics Core
- Hangzhou Chengyuan Genomics
- Harvard College
- Harvard University
- Huntsman Cancer Institute (University of Utah)
- Illumina
- Imperial BRC Genomics Facility (Imperial College London)
- Imperial Life Sciences
- InCellDx
- Indiana University School of Medicine (Indiana University)
- Institute for Genome Sciences (University of Maryland School of Medicine)
- Institute for Molecular Bioscience (University of Queensland)
- Intermountain Healthcare
- Iowa Institute of Human Genetics (University of Iowa)
- IsoPlexis
- Johnson & Johnson
- Katholieke Universiteit Leuven
- Kinghorn Medical Center (Garvan-Weizmann Medical Center)
- LC Sciences
- LMU University Hospital
- LumaCyte
- Massachusetts General Hospital
- Massachusetts Institute of Technology
- University of Texas MD Anderson Cancer Center
- MedGenome
- MGI
- MilliporeSigma
- Minos Biosciences
- Mission Bio
- Monash Health Translation Product Medical Genomics Facility
- NanoString Technologies
- Nashville Biosciences
- Natera
- NeuroInDx
- nference
- Novogene
- Nucleome Informatics
- NXTGNT (Ghent University)
- OICR Genomics and Bioinformatics
- Onconova Therapeutics
- Ottawa Hospital Research Institute
- Oxford Genetics (University of Edinburgh)
- Oxford Genomics Centre (University of Oxford)
- Oxford Nanopore Technologies
- Pacific Biosciences
- Partek
- Peak Analysis and Automation
- Perelman School of Medicine (University of Pennsylvania)
- PerkinElmer
- Petri
- Pittsburgh Liver Research Centre (University of Pittsburgh)
- Princess Margaret Genomics Centre
- Proteona
- Psomagen
- QB3 Genomics (University of California, Berkeley)
- QIAGEN
- Quick Biology
- Ramaciotti Centre for Genomics
- ReadCoor
- Rockefeller University
- RootPath
- S2 Genomics
- Saban Research Institute
- Salk Institute of Biological Sciences
- Sanford Burnham Prebys Medical Discovery Institute
- Scailyte
- SciLifeLab
- Scipio Bioscience
- Semel Institute for Neuroscience and Behavior (University of California)
- SeqLL
- SeqMatic
- Sequencing Core Facility (Max Planck Institute for Molecular Genetics)
- seqWell
- Singleron Biotechnologies
- Single Cell Analysis Facility (NCI Frederick Accessioning)
- Single Cell Discoveries
- Single Cell Genomics Core (Baylor College of Medicine)
- Single Cell Genomics Core (Brigham and Women's Hospital)
- Single Cell Sequencing Core - Department of Medicine (Boston University)
- Singlera Genomics
- SingulOmics
- Spanish National Center for Cardiovascular Research
- Spatial Transcriptomics
- Sphere Fluidics
- Split Bioscience
- St. Jude Children's Research Hospital
- Stanford University
- Sylvester Comprehensive Cancer Center (University of Miami)
- Takara Bio
- Technology Center for Genetics and Bioinformatics (University of California)
- Turku Bioscience (University of Turku)
- University of Auckland
- University of Buffalo Genomics and Bioinformatics Core
- University of California
- University of Helsinki
- University of Kansas Medical Center
- University of Oxford
- University of Texas
- UT Southwestern Medical Center (University of Texas)
- Vanderbilt Technologies for Advanced Genomics
- VIB Nucleomics Core (VIB)
- VyCAP
- WaferGen Bio-systems
- Wellcome Sanger Institute
- Wexner Medical Center (Ohio State University)
- Wistar Institute
- X Gen
- Yale Center for Genome Analysis (Yale School of Medicine)
- Yerkes National Primate Research Center (Emory University)
- Zephyrus Biosciences
- Zomedica Pharmaceuticals
Methodology
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