Course overview
The microbiome plays an important role in many diseases and holds promise of being a therapeutic target, or key, of high clinical relevance. However, the metholodogy of the science of microbiomics is very unlike what is typically used in clinical trials: big data, computationally-demanding bioinformatics, highly multivariate results, skewed distributions, complex assumptions. In addition, the field is held back by a lack of standardisation.
What is the clinical relevance of the microbiome? What is the current status of microbiomics in clinical trials? What interpretational pitfalls should one be wary of in the field of microbiomics? How can current best practices best be applied in a microbiome context? How does one validate the results of microbiomics?
These are some of the questions that this course will seek to shed some light on.
CPD Hours: 3
Course Content
- Day 1
- An introduction to the microbiome and its broad clinical relevance
- The basics of microbiomics methodology and data
- Microbiomics in clinical trials to date
- Data integrity of big data
- Validation and standardization of microbiomics methods
Speakers
Nikolaj Sørensen
Nikolaj Sørensen holds a MSc in biology and PhD in microbial ecology form the University of Copenhagen. He has worked with microbiomics for 10 years, both executing and leading laboratory and bioinformatic efforts, and has authored several papers on the subject and worked on several clinical trials. Currently, Nikolaj Sørensen focuses on bringing microbiomics into medicine, facilitating that process from a QA perspective.
