Synthetic Biology enables the capability to manipulate and modify leaving cells and organisms to program them for specific purposes and has the potential to change the course of the healthcare sector. Synthetic Biology and its Consequences in Present Healthcare presents the latest findings and applications those in the healthcare sector need. Chapters cover a variety of synthetic biological tools in lifestyle diseases like obesity, heart disease, liver disease, type 2 diabetes and more. In addition, the vaccine development will cover DNA vaccines, synthetic and modified RNA-based vaccines, and personal vaccines for cancer, thus filling a gap in literature in the synthetic biology space. Written by international experts in the fields for those researching, practicing or studying in life sciences, biological sciences, including the synthetic biology domain.
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Table of Contents
1. An introduction of synthetic biology and important milestonesSubhajit Das and Ayan Chatterjee
2. Applications of genome synthesis and editing in synthetic biology
Himel Mondal, Shaikat Mondal, Sairavi Kiran Biri and Shreya Sharma
3. Application of xenonucleotide in synthetic biology
Rajdip Goswami, Sourin Saha, Nilanjan Sarkar, Arvind Kumar, Kalyan Roy and Mainak Chakraborty
4. Application of cell-free system in synthetic biology
Bhupendra Prajapati, Neelakanta Sarvashiva Kiran, Chandrashekar Yashaswini and Ankita Chatterjee
5. Application of computational methods and artificial intelligence in synthetic biology
Naga Bhushana Rao Karampudi
6. Application of synthetic biology in bioactive peptide designing
Rupsha Karmakar, Atasi Hazra, Souradip Basu, Mahashweta Mitra Ghosh and Sayak Ganguli
7. Application of synthetic biology in vaccine development
Ayon Dutta, Dipanjana Ash, Biswajit Basu and Bhupendra Prajapati
8. Application of synthetic biology in novel drug delivery system
Rajdip Goswami, Saikat Santra, Meghamouli Rana, Bhaskar Pal, Mainak Chakraborty, Biswajit Basu and Bhupendra Prajapati
9. Application of synthetic biology in engineered therapeutic antibodies
Neeraj Soni, Deepika Trakroo, Madhurjya Protim Borah and Mithu Baidya
10. Application of synthetic biology in mammalian cell-based therapies and cancer
Krishnendu Adhikary, Riya Dey, Prity Chatterjee, Sucheta Chatterjee, Baisakhi Mukherjee and Farzad Taghizadeh-Hesary
11. Application of synthetic biology in infectious and communicable diseases
Sayantan Kundu, Shilpa Chatterjee, Biswajit Basu and Bhupendra Prajapati
12. Application of synthetic biology in genetic disorder
Reyed M. Reyed, Riya Patel, Shivani Patel and Bhupendra Prajapati
13. Application of synthetic biology in lifestyle disease
Piyali Khamkat, Bramhajit Chatterjee, Vivek Barik, Swarupananda Mukherjee, Biswajit Basu and Bhupendra Prajapati
14. Application of synthetic biology in age-related and neurodegenerative disease
Sourav Ghosh, Sayantan Kundu, Riya Jana, Biswajit Basu and Bhupendra Prajapati
15. Application of synthetic biology in biosynthesized pharmaceuticals
Dipanjana Ash, Ayon Dutta, Biswajit Basu and Bhupendra G. Prajapati
16. Application of synthetic biology in biosensors
Subhadip Chakraborty
Authors
Bhupendra G. Prajapati Parul Institute of Pharmacy, Faculty of Pharmacy, Parul University, Waghodia, Vadodara, Gujarat, India. Dr. Bhupendra Gopalbhai Prajapati is Professor (Research Cadre) at Parul Institute of Pharmacy, Parul University, Gujarat, India, and serves as Adjunct Professor in the Department of Industrial Pharmacy at Silpakorn University, Thailand. His academic, research, and industry expertise focuses on lipid-based formulations, nano- and microparticulate drug delivery systems, and strategies to enhance drug bioavailability. Dr. Prajapati has received several academic and professional honors recognizing excellence in teaching and research. He has made substantial scholarly contributions through research and review publications, book chapters, and edited volumes in pharmaceutical sciences. Actively engaged in postgraduate and doctoral mentoring, he supports research training in advanced drug delivery and formulation science. Dr. Prajapati also serves in editorial and section-editor roles for international scientific publications, contributing to the advancement and quality of pharmaceutical research dissemination. Biswajit Basu Professor, Adamas University, India.Prof. Basu is an academician, researcher, and professor in India with more than 16 years of teaching experience. He is dedicated and distinguished service as a teacher and has authored two books and 16 book chapters in pharmaceutical sciences (Elsevier, Apple Academic Press, Wiley, Springer). He has to his credit over 39 publications in reputed pharmaceutical Journals and has supervised 22 M. Pharm. candidates, currently supervising 4 M. Pharm., and 4 Ph.D. candidates. He has been a reviewer for several international and national research journals and a life member of IPA and APTI. He has been awarded the "Young Achiever Award 2021� & "Young Researcher Award 2022� from the Institute of Scholar Award in 2021 & 2022. He has been awarded the "Award for Excellence in Research� from the National Education Brilliance Award 2021, in recognition of and appreciation for his outstanding contribution to education.
Anirudha Dutta Assistant Professor, Department of Biological Sciences, Adamas University, India.Dr. Anirudha Dutta is currently working as Assistant Professor at Department of Biological Sciences, Adamas University, India. Dr. Dutta has 8 years of research and teaching experience. He has authored multiple peer reviewed research articles in various international SCI indexed journals and book chapters. He has published principal authored articles in high impact journals like Journal of Biological Chemistry, FEBS Journal, etc.
Ayan Chatterjee Associate Professor and Associate Dean of School of Health Science and Technology, Medhavi Skills University, Sikkim, India. Dr. Ayan Chatterjee is currently working as Associate Professor and Associate Dean of School of Health Science and Technology, Medhavi Skills University, Sikkim, India. He also has teaching experience in Human Physiology, Biochemistry and allied subjects at Undergraduate, Postgraduate and Diploma level for 12 years. He has authored 96 full length research papers, book chapters and also presented papers at International and National Conferences.
