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Innovative Nanocarriers for Stimulated Drug Delivery. A Comprehensive Guide to Stimuli-responsive Nanoparticles

  • Book

  • July 2026
  • Elsevier Science and Technology
  • ID: 6250368
Innovative Nanocarriers for Stimulated Drug Delivery: A Comprehensive Guide to Stimuli-responsive Nanoparticles summarizes recent advances and achievements in nanocarriers responsive to external or internal stimuli. The book presents different stimuli-sensitive strategies and their applications in drug delivery, therapy, and theranostics. Sections provide fundamental knowledge on the experiential and experimental aspects of stimuli-responsive nanocarriers, discuss external-responsive nanocarriers for biomedical applications, such as ultrasound, thermal, magnetic, light, and electric field-response systems, and describe internal stimuli-responsive nanocarriers for biomedical applications, including pH, hypoxia, redox potential, enzyme, glucose, and microRNA-responsive nanocarriers.

Additionally, the book covers dual and multimodal-responsive nanocarriers and the therapeutic aspects of stimuli-responsive nanocarriers, such as metallic and non-metallic stimuli-responsive nanocarriers in the treatment of various cancer and noncancerous diseases. Finally, recent advances and regulatory aspects of stimuli-responsive nanocarriers, including clinical translation, challenges, biological toxicity, safety issues, clinical trials, and future perspectives are covered.

Table of Contents

Part I Foundations of stimuli-responsive nanocarriers
1. Fundamental of stimuli-responsive materials in drug delivery
2. History, introduction, and physicochemical properties and characterization parameters of stimuli-responsive nanocarriers

Part II External-responsive nanocarriers for biomedical application
3. Ultrasound-responsive nanocarriers for biomedical application
4. Thermal-responsive nanocarriers for biomedical application
5. Magnetic-responsive nanocarriers for biomedical application
6. Light-sensitive nanocarriers for biomedical application
7. Electric field-response systems for biomedical application

Part III Internal stimuli-responsive nanocarriers for biomedical application
8. pH-responsive nanocarriers for biomedical application
9. Hypoxia-responsive nanocarriers for biomedical application
10. Redox-responsive nanocarriers for biomedical application
11. Enzyme-responsive nanocarriers for biomedical application
12. Glucose-responsive nanocarriers for biomedical application
13. microRNA responsive nanocarriers for biomedical application

Part IV Dual and multimodal-responsive nanocarriers for biomedical application
14. Temperature and pH dual-stimuli-responsive nanocarriers for biomedical application
15. pH and redox potential dual-stimuli-responsive nanocarriers for biomedical application
16. Dual-stimuli-responsive nanocarriers for biomedical application
17. Stimuli-responsive charge-reversal nanocarriers for biomedical application
18. Stimuli-responsive nanocarriers for image-guided therapy

Part V Therapeutic aspects of stimuli-responsive nanocarriers
19. Metallic stimuli-responsive nanocarriers in the treatment of various cancer
20. Non-metallic stimuli-responsive nanocarriers in the treatment of various cancer
21. Metallic stimuli-responsive nanocarriers in the treatment of noncancerous disease
22. Non-metallic stimuli-responsive nanocarriers in the treatment of noncancerous disease

Part VI Recent advances and regulatory aspects of stimuli-responsive nanocarriers
23. Clinical translation, challenges, biological toxicity and safety issues associated with stimuli-responsive nanocarriers
24. Recent updates on clinical trials associated with stimuli-responsive nanocarriers
25. Limitations, hurdles conclusion and future prospective of stimuli-responsive nanocarriers

Authors

Prashant Kesharwani Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya University, Sagar, Madhya Pradesh, India.

Dr. Prashant Kesharwani is assistant professor of Pharmaceutics at Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya University, Sagar, Madhya Pradesh, India. He has more than 12 years of teaching, research, and industrial experience across various countries. An overarching goal of his current research is the development of nanoengineered drug delivery systems for various diseases. He has published many articles in well-reputed journals and a large number of books. He is a recipient of many research grants from various funding bodies. He is also the recipient of several internationally acclaimed awards, such as "USERN Laureate award�, and "SERB-Ramanujan Fellowship Award�. He has presented many invited talks and oral presentations at prestigious scientific peer-conferences, received international acclaims and awards for research contribution, supervised students/junior researchers and actively participated in outreach and scientific dissemination for the service of the wider community.