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Advances in Diffusion Magnetic Resonance Imaging for Neurodegenerative Diseases Research

  • Book

  • June 2026
  • Elsevier Science and Technology
  • ID: 6250644

Advances in Diffusion Magnetic Resonance Imaging for Neurodegenerative Diseases Research covers how diffusion MRI has contributed to our understanding of common neurodegenerative diseases, bridging common microstructural changes across symptoms and disorders. Sections cover the technical basis of diffusion MRI, focusing on the interpretation of its imaging-derived metrics in terms of neuronal damage. Subsequent chapters are organized by disease, taking an in-depth look at how the use of diffusion MRI has contributed to recent understanding, and how it has motivated potential new therapeutic structures for Alzheimer’s disease, frontotemporal dementia, primary aggressive aphasia, Parkinson’s disease, progressive supranuclear palsy, Huntington’s disease, and more.

The book concludes with implications for future research, making it a must-have reference for researchers and clinicians interested in the field of neuroimaging for neurodegenerative disorders.

Table of Contents

  1. ?Introduction to diffusion MRI in neurodegenerative disorders
  2. ?Advances in diffusion MRI in Alzheimer’s disease
  3. ?Advances in diffusion MRI in frontotemporal dementia
  4. ?Advances in diffusion MRI in Parkinson’s disease
  5. ?Advances in diffusion MRI in Huntington’s disease
  6. ?Advances in diffusion MRI in progressive supranuclear palsy
  7. ?Advances in diffusion MRI in multiple system atrophy
  8. ?Advances in diffusion MRI in neurodegenerative cerebellar ataxias
  9. ?Advances in diffusion MRI in motor neuron diseases
  10. ?Advances in diffusion MRI in multiple sclerosis
  11. ?Concluding remarks and implications for future research

Authors

Frederic Sampedro University Hospital of Sant Pau, Radiology Department, Barcelona, Spain. ??Frederic Sampedro, MD, PhD, BEng, MBA. Medical Doctor (MD), Computer Scientist BSc (Honors), Biomedical Engineer MSc, Electrical Engineer MSc, Artificial Intelligence MSc and MBA in Tech-based business administration, has a PhD in medical image analysis (extraordinary doctorate award) and over 15 years research experience in medical imaging, with a focus on computational neuroimaging of neurodegenerative disorders. He has over 80 indexed journal papers (~40 as first or corresponding author), total IF >400, h-index>22, >1200 citations and is director of several PhD theses and reviewer for multiple top journals in this field. He is a visiting lecturer at several universities and research institutes in Spain. Frederic Sampedro is a member of the Editorial Board of the?Journal of Neuroradiology, official publication of the French Society of Neuroradiology (SFNR).?