This is a valuable resource to researchers and scientists interested in the application of nanotechnology for improved cancer therapy as it provides a thorough overview of real-world applications and future research trends as well as a discussion on overcoming challenges in mitochondrial targeting.
Table of Contents
1. Introduction of nanotechnology: basic concept and properties2. Basics of cancer biology, and role of nanotechnology in cancer treatment
3. Nanoparticle-Mediated Drug Delivery in Cancer Therapy: Addressing Drug Resistance Challenges
4. Advancing Targeted Drug Delivery in Malignancy: Nanoengineering Strategies for Enhanced Efficacy
5. Mitochondria in Cancer: Functions, Dysfunction, and Therapeutic Targets
6. Introduction to mitochondria-targeted Drug Delivery in cancer
7. Mitochondria-Targeted Drug Delivery Strategies for Cancer Treatment
8. Mitochondria-Targeted Liposomes in Cancer Therapy
9. Mitochondrial-Targeted Photosensitizers Nanoparticles in Photodynamic Therapy
10. Role of Mitochondria-Penetrating Peptides in Cancer Therapeutics
11. Modulating Mitochondrial Reactive Oxygen Species in Cancer Therapy through Nanomaterials
12. Polymeric Nanoparticles for Mitochondria Targeting Mediated Robust Cancer Therapy
13. Characterization of Mitochondria-Targeted, Nanoparticle-Based Drug-Delivery System
14. Nanoplatforms: Overcoming Challenges in Mitochondrial Targeting for Effective Cancer Treatment
15. Future directions and emerging trends of Mitochondria-Targeted Drug Delivery Strategies: Challenges and future prospects
16. Clinical trials, toxicity studies and real-world applications of mitochondria-targeted drug delivery strategies
Authors
Arun Kumar Singh Assistant Professor, Vivekanand Global University, India. Arun Kumar Singh is an Assistant Professor in the Department of Pharmacy at Vivekanand Global University, India. He completed his M.Pharm in Pharmaceutics from Galgotias University, Greater Noida. His research interests include nano-formulation, blockchain, IoT, machine learning, artificial intelligence, big data analytics, cancer biology, and neuroscience. He has contributed to academic books and book chapters and has published review articles in the areas of pharmaceutical sciences and healthcare technology. His work focuses on interdisciplinary approaches integrating pharmaceutical research with emerging digital and computational technologies. Neeraj Mishra Professor and Head of Department, Department of Pharmaceutics, Amity Institute of Pharmacy, Amity University, Gwalior, Madhya Pradesh, India.Dr. Neeraj Mishra is Professor and Head of the Department of Pharmaceutics at the Amity Institute of Pharmacy, Gwalior. He has over 20 years of teaching and research experience in pharmaceutics, with particular expertise in novel drug delivery systems, localized and targeted drug delivery, and nanocarrier-based therapeutics for disease. His formulations and controlled delivery approaches are aimed at improving therapeutic outcomes. Dr. Mishra has supervised postgraduate and doctoral research scholars, has contributed widely to academic literature through research publications, books, and book chapters with leading international publishers. He has won several awards including Outstanding Scientist Award, and Distinguished Professor Award. He is associated with innovation in pharmaceutical sciences through patented research contributions. Over the course of his career, he has received several academic and scientific recognitions for his contributions to teaching, and research. He has been recognized internationally for his research impact and scholarly contributions.
Ashutosh Pareek Professor, Department of Pharmacy, Banasthali Vidyapith, Banasthali, Tonk, Rajasthan, India.Dr. Ashutosh Pareek, Professor at Banasthali Vidyapith with over 15 years of experience in pharmaceutical sciences, holds gold medals for his Master's and Bachelor's degrees in Pharmacy. Dr. Pareek specializes in neuropharmacology and innovative drug delivery systems, focusing on neurodegenerative disorders, cancer, and autoimmune diseases. His research includes developing advanced drug delivery systems for immunomodulators like naringenin. Dr. Pareek leads a research team working on these critical health issues and has published over 45 research papers and authored five technical books. He holds an international formulation patent and has received numerous awards, including the Zee National Achievers Award 2023. His work is funded by national and international agencies such as ICMR, DST-SERB, DBT, the American Association of Pharmaceutical Scientists, and the International Brain Research Organization. He serves as a Review Editor for Frontiers in Pharmacology and Frontiers in Oncology and reviews for leading journals by Elsevier, Springer, and Bentham.
Anoop Kumar Assistant Professor, Delhi Pharmaceutical Sciences and Research University (DPSRU), India.Dr. Anoop Kumar is an Assistant Professor in the Department of Pharmacology at Delhi Pharmaceutical Sciences & Research University (DPSRU), India. With a distinguished career, he has previously served as an Assistant Professor and Head at the National Institute of Pharmaceutical Education and Research (NIPER), Raebareli, and as Head and Associate Professor at ISF College of Pharmacy, Moga, Punjab. Dr. Kumar has also held research positions at Sun Pharmaceutical Industries Limited and Translational Health Science Institute (THSTI). He earned his Ph.D. from Birla Institute of Technology, Mesra, Ranchi, as a DST INSPIRE Fellow. He is an Associate Editor for Health Sciences Review and Acta Neurologica Scandinavica. His research focuses on drug repurposing, clinical trial meta-analysis, pharmacoeconomics, and pharmacovigilance.
Gautam Sethi Associate Professor, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Dr. Gautam Sethi is a tenured Associate Professor in the Department of Pharmacology at the Yong Loo Lin School of Medicine, National University of Singapore. His research focuses on elucidating the molecular mechanisms underlying cancer initiation and progression, particularly the activation of oncogenic transcription factors by carcinogens and inflammatory agents, and the identification of novel therapeutic inhibitors. Dr. Sethi has made substantial and direct scholarly contributions to the fields of gut microbiota, cancer pathophysiology, and host-microbiome interactions, with particular emphasis on immunotherapy, tumor microenvironment modulation, metabolic signaling, and therapy response prediction. He has authored numerous peer-reviewed research and review articles in high-impact journals, received multiple international awards, and serves on the editorial boards of more than 15 international journals.
