By detailing how flavonoids counteract cancer stemness and influence immune responses, this book offers innovative insights into utilizing plant-derived compounds for cancer treatment. It stands out by providing a detailed overview of flavonoids' cellular and molecular mechanisms while also evaluating the pros and cons of current therapeutic options, making it essential reading for a global audience.
Table of Contents
1. Recent Update on Cancer Epidemiology2. Pros and Cons of Currently Available Chemotherapy
3. Flavonoids, Their Classification, Chemistry, and Therapeutic Potential Against Different Types of Cancer
4. Source of Flavonoid, Mode of Intake, Bioavailability and Possible Toxicity
5. Flavonoids Against Immune Evasion During Carcinogenesis
6. Apoptosis Inducing Potential of Flavonoids in Cancer
7. Flavonoids As Cell Cycle Inhibitors in Cancer
8. Flavonoids with Anti-angiogenetic Potential in Cancer
9. Flavonoids As Promising Plant Derived Agents Against Cancer Invasion and Metastasis
10. Promising Function of Flavonoid in the Inhibit of Epithelial to Mesenchymal Transition
11. Flavonoids Mediated Regulation of Cancer Stemness Phenotype
12. Role of Flavonoids in Epigenetic Regulation: A Mechanism for Their Anti-cancer Potential
13. Synergistic Effects of Flavonoids with Other Anti-cancer Drugs: With Special References to Targeted and Immunotherapy
14. Clinical Implication of Flavonoid: Integration with Clinical Trials and Future Directions
Authors
Dharambir Kashyap Brown Center for Immunotherapy, Melvin and Bren Simon Comprehensive Cancer Center, Division of Hematology and Oncology, School of Medicine, Indiana University, Indianapolis, IN, USA.Dr. Kashyap is currently at the Brown Center for Immunotherapy, Indiana University, working on identifying novel biomarkers for designing and modifying immunotherapy approaches for breast cancer targeting TME components. He received his PhD in molecular biology on the main subject of tumor microenvironment in breast cancer from PGIMER, Chandigarh, India, and holds an MSc in Human Genomics. He published 70 articles and five book chapters. He is also a reviewer and editorial board member of many PubMed/Scopus-indexed journals. His h-index is 26, and FWCI is 2.91
Riya Sharma Melvin and Bren Simon Comprehensive Cancer Center, Division of Hematology and Oncology, School of Medicine, Indiana University, Indianapolis, IN, USA.Dr. Sharma is an early career scientist in biological science at the School of Medicine, Indiana University Indianapolis, USA, working on Multiple Myeloma genomics characterizations. She holds an MSc in Microbial Biotechnology and has good publications in peer-reviewed international journals.
