Readers will find detailed discussions on emerging MRI methods, including dynamic contrast, arterial spin labeling, and quantitative BOLD models. The book also addresses the functional impact of physiological changes on tissue microstructure and integrity, offering insights into multiparametric relaxation mapping and quantitative susceptibility mapping. Uniquely, this book gives a comparative approach to different brain physiological MRI methods, highlighting their strengths, limitations, and reliability.
Table of Contents
1. Overview of brain physiology and systems anatomy (as related to neuroimaging)2. Overview of brain physiology and systems function
3. Microvascular brain physiology and perfusion imaging
4. Macrovascular brain physiology and hemodynamic timing
5. Cerebrovascular reserve and autoregulation
6. Neurovascular coupling and tissue metabolism
7. Cerebrospinal fluid pathways and flow imaging
8. Glymphatics and Blood Brain Barrier physiology
9. Functional/physiological coordination of hemodynamic systems
10. Functional impact on tissue microstructure and integrity
Authors
Audrey P. Fan University of California, Davis, USA.Audrey Fan develops new magnetic resonance imaging (MRI) and positron emission tomography methods to measure brain physiology and function. Dr. Fan is a Junior Fellow of the International Society of Magnetic Resonance in Medicine and currently co-leads the Imaging Core for the Alzheimer's Disease Research Center at UC Davis Health. Her overall goal is to bridge engineers in her lab with clinicians and scientists to advance neuroimaging technology and promote brain vascular health across the entire lifespan.
Ahmed Khalil Charite Center for Stroke Research, Berlin, Germany.Dr. Ahmed Khalil is a clinician-scientist in the Institute of Neuroradiology at the Charit� - Universit�tsmedizin Berlin. His research focuses on developing and clinically validating novel magnetic resonance imaging (MRI) techniques to assess brain hemodynamics, tissue oxygenation, and blood-brain barrier function. With a particular interest in the pathophysiology of stroke and cerebrovascular diseases, Dr. Khalil's work bridges the gap between technical MRI methods and their clinical application to improve patient diagnosis and clinical decision-making. Beyond his primary research, he is an advocate for reproducible science, medical education, and science communication, and is an avid science writer and blogger. He holds postgraduate degrees in internal medicine and neuroscience from institutions across the UK, France, and Germany.
