Network Pharmacology: Exploring New Horizons in Drug Discovery explores the innovative network pharmacology approach-which examines the intricate interactions between disease targets and metabolites-offering a systems-based perspective that is essential for modern drug discovery. Readers will find in-depth discussions on metabolite databases, computational tools, and the role of natural products in drug discovery. Notable topics include network-based approaches to drug repurposing, personalized medicine, and the implications of traditional medicine in pharmacological research, all supported by real-world case studies and advanced computational methodologies.
By integrating multiomics data, including metabolite profiling, the book addresses the limitations of conventional methods and opens new pathways for understanding disease mechanisms and therapeutic responses. This is a foundational guide for researchers, pharmaceutical scientists, and academic scholars across diverse fields such as pharmacology, metabolomics, and systems biology.
Table of Contents
Section 1: Foundations and Tools in Network pharmacology 1. Introduction to Network Pharmacology and Metabolites in Drug Discovery 2. Integrating Network Pharmacology with Metabolomics 3. Metabolite Databases and Computational Tools
Section 2: Applications and Innovations 4. Network Pharmacology in Natural Products and Herbal Formulations 5. Pharmacokinetics and Metabolite-Drug Interactions 6. Omics Technologies in Network Pharmacology 7. Network-Based Approaches to Drug Repurposing 8. Network Pharmacology in Personalized Medicine 9. The role of Traditional medicine (TCM, AYUSH, Thai, etc) in Network pharmacology
Section 3: Emerging Trends and Future Directions 10. Bioinformatics and Network pharmacology: Advancing Drug Discovery with AI and Big Data 11. Network pharmacology and molecular docking (In silico and dynamic simulation) 12. Clinical Applications of Network Pharmacology: Emphasizing Toxicity Prediction and Safety 13. Challenges and Future Perspectives
Authors
Veeranoot Nissapatorn Futuristic Science Research Center, School of Science, Walailak University, Nakhon Si Thammarat, 80160, Thailand.
Dr Veeranoot graduated with MBBS from Lady Hardinge Medical College (LHMC), University of Delhi, India and Master of Clinical Tropical Medicine from Mahidol University, Thailand. She was working as a contract lecturer and later an Associate Professor at the Department of Parasitology, Faculty of Medicine, University of Malaya, Malaysia for almost two decades (from 1999 to 2017). She is now working as an Associate Professor at the School of Allied Health Sciences, Walailak University, Thailand. Dr Veeranoot is actively involved in her research areas of interest: 1). Clinical Tropical Medicine, 2). Diagnostic challenges, 3). Natural products, 4). Water-based research, and 5). One-Health for Sustainability. Dr Veeranoot is a coordinator of 2 international research networks (IRN); Southeast Asia Water Team (SEA Water Team) and World Union for Herbal Drug Discovery (WUHeDD). Also, she has published more than 150 papers including book chapters and is an editorial board member of reputable journals as well as an active reviewer of more than 60 international journals. She also serves as the Editor (Guest, Academic and Associate), Editor in Chief for Infectious Disorders-Drug Targets Journal, Speaker, Adjunct faculty, Guest lecturer, as well as Visiting Professor.
Ragini Bodade Institute of Advanced Study in Science and Technology (IASST), India.
Dr. Ragini Bodade is currently working as Associate Professor at Life Sciences Division Institute of Advanced Study in Science and Technology (IASST), Guwahati, Assam. She received M.Sc. Ph. D. in Microbiology from School of Life Sciences, Swami Ramanand Teerth Marathwada University, Nanded, Maharashtra. Before joining IASST, she served as Assistant Professor at the Department of Microbiology, Savitribai Phule Pune University, Pune, Maharashtra. She has more than ten years of teaching and five year of research experience. She is also an awardee of UGC research fellowships like Rajiv Gandhi National Fellowship and Dr D S Kothari post doctorate fellowship. She has also attended several conferences at National and International level and presented her research. Dr Ragini's research area includes Applied microbiology and Biomedicine. She mainly focuses on secondary metabolites screening for Antihyperuricemic diseases management through computational biology.
Asis Bala Institute of Advanced Study in Science and Technology (IASST), India.
Dr Asis Bala is currently working as Associate Professor at Life Sciences Division Institute of Advanced Study in Science and Technology (IASST), Guwahati, Assam. He received his M. Pharm Ph.D. (Pharmacy) from Jadavpur University, Kolkata, West Bengal. Before joining IASST, he served as Assistant professor at Guru Nanak Institute of Pharmaceutical Science and Technology Kolkata, National Institute of Pharmaceutical Education and Research Hajipur, and Faculty fellow at University of the Free State: Bloemfontein, Free State, ZA.Dr Asis has also awarded with prestigious Edward Moore Kennedy Memorial award, and as best reviewer award by Bentham and Elsevier.
Roma Pandey IILM University, India.
Dr. Roma Pandey is an Assistant Professor in the Department of Biotechnology at IILM University, Greater Noida, with a strong academic and research background in plant molecular biology and biotechnology. She holds a Ph.D. in Biotechnology from Bennett University and has made significant contributions to academia and research, with over eight years. Dr. Pandey was awarded the FITM Doctoral Research Fellowship by the Ministry of AYUSH for her groundbreaking work on developing standardized post-harvest processing guidelines for medicinal plants. Dr. Pandey has also been a recipient of the Science Academies' Summer Research Fellowship.
Anand Gaurav University of Petroleum and Energy Studies, India.
Prof Dr Anand Gaurav is currently working as Professor and Research Coordinator at School of Health Sciences and Technology, University of Petroleum and Energy Studies (UPES) Dehradun. He received his B.Pharm from Sardar Patel University, His M.Tech from Indian Institute of Information Technology-Allahabad, M.Pharm from Maharaja Sayajirao University of Baroda and PhD from Shobhit University. Before joining UPES Dehradun, he served as Associate Professor at the Faculty of Pharmaceutical Science, UCSI University, Kuala Lumpur, Malaysia. His academic career includes stints at various institutions in India and abroad. He has also served as a Visiting Professor to UCSI University, Malaysia, Anton De Kom Universiteit van Suriname, South America and Villa College, Maldives.
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