Table of Contents
1. General Introduction to Drug Resistance in Cancer2. Genomic and Epigenomic Factors in Drug Resistance
3. Role of the Tumor Microenvironment
4. Technological Advances in Single-Cell Analysis
5. Advances in Organoids and 3D Models
6. Drug Development and Resistance Testing
7. Artificial Intelligence and Machine Learning in Drug Resistance Research
8. Computational Modelling in Cancer Resistance
9. Emerging Therapies for Overcoming Resistance
10. Resistance Mechanisms in Rare and Pediatric Cancers
11. Case Studies and Clinical Applications
12. Overall Conclusions and Future Perspectives

