Modern Bioinformatics. From Molecular Insights to Biomedical Innovation

Table of Contents

Part I. Exploring the World of Bioinformatics and Molecular Structures
1. Introduction to Bio-informatics
2. Fundamentals of Protein structure
3. Fundamentals of DNA and RNA structure
4. Nano-molecular structure determination
5. Molecular visualisation

Part II. Advancements in Bioinformatics: From Molecular Structures to Functional Insights
6. Identifying structural domains in proteins
7. Inferring protein function from structure
8. Genome biology
9. Deep Learning for Protein Structure Prediction: The Case of AlphaFoldDeep Learning for Protein Structure Prediction: The Case of AlphaFold

Part III. Molecular Interactions and Computational Approaches in Bioinformatics
10. AI and Machine Learning in Genomics and Structural Bioinformatics
11. Protein- Nucleic acid interactions
12. Protein- protein interactions
13. Docking methods, ligand design

Part IV. Computational Techniques and Applications of Bioinformatics in Structural Biology and Drug Discovery
14. Homology modelling
15. RNA structural bioinformatics
16. Bioinformatics in drug discovery
17. Precision Medicine and Bioinformatics Applications

Part V. Forensic Bioinformatics: Techniques and Data Analysis in Molecular Biology
18. Forensic molecular biology
19. DNA extraction techniques
20. Statistical presentation of forensic data
21. Case Studies in Forensic Bioinformatics Applications

Part VI. Molecular Biology and Bioinformatics: From Genetic Engineering to Protein Evolution
22. Recombinant DNA and molecular cloning
23. RNA processing
24. Proteins: structure, function and evolution

Part VII. Nanotechnology and Quantum Innovations in Molecular Diagnostics and Biosensing
25. Nano arrays for molecular diagnostics
26. Nano-biosensors
27. Detection of biomarkers by nano-technology
28. Clinical applications of nano diagnostics
29. Quantum biosensors
30. Quantum Computing in Bioinformatics: Concepts and Applications

Part VIII. Computational Strategies and Biomarker Insights in Drug Discovery and Development
31. Computational approaches to drug target identification
32. Translational biomarkers in drug development
33. Data visualization and DDP process
34. Clinical trial failures and drug repositioning
35. Computational phenotypic assessment

Authors

Kolla Bhanu Prakash Professor and Research Group Head, CSE Department, KL University, India. Dr. Kolla Bhanu Prakash is a Professor and Research Group Head in the CSE Department, KL University, India. His current research interests include Deep Learning, Data Science, Smart Grids and Image Processing. Saurav Mallik Research Scientist, Department of Pharmacology and Toxicology at The University of Arizona, USA. Dr. Saurav Mallik is a Research Scientist in the Department of Pharmacology and Toxicology at The University of Arizona, USA. He previously served as a Postdoctoral Fellow at Harvard T.H. Chan School of Public Health (2019-2022) and held positions at the University of Texas Health Science Center at Houston (2018-2019) and the University of Miami Miller School of Medicine (2017-2018). Dr. Mallik earned his PhD in Computer Science and Engineering from Jadavpur University, India, in 2017, conducting research at the Indian Statistical Institute. He received a Research Associateship from CSIR, India, in 2017. With over 150 publications in high-impact journals, he has authored several books and patents. Dr. Mallik is an active member of IEEE, ACM, AACR, and Bioclues, and has collaborated with editors and reviewers for prestigious journals. His research focuses on Computational Biology, Bioinformatics, Bio-Statistics, and Machine Learning. Valentina Emilia Balas Department of Automatics and Applied Software, Faculty of Engineering, "Aurel Vlaicu� University of Arad, Arad, Romania Academy of Romanian Scientists, Romania. Valentina Emilia Balas is currently a Full Professor in the Department of Automatics and Applied Software at the Faculty of Engineering, "Aurel Vlaicu� University of Arad, Romania. She holds a PhD cum Laude in Applied Electronics and Telecommunications from the Polytechnic University of Timisoara. Dr. Balas is the author of more than 350 research papers. She is the Editor-in-Chief of the 'International Journal of Advanced Intelligence Paradigms' and the 'International Journal of Computational Systems Engineering', an editorial board member for several other national and international publications, and an expert evaluator for national and international projects and PhD theses.