Polyphenols in Wound Healing presents a comprehensive exploration of how naturally occurring compounds-polyphenols-play a pivotal role in advancing wound care therapies. Divided into four thoughtfully curated sections, the book begins with an in-depth review of the science of wound healing, introducing readers to the fundamentals of skin physiology, the various types of wounds, and key therapeutic targets. Other sections delve into the world of polyphenols, offering detailed information on their natural sources, especially medicinal plants, and the techniques used for their extraction, isolation, and purification. A focus on how polyphenols act on biological pathways to support wound healing is also included.
This includes mechanisms such as reducing inflammation, combating oxidative stress, modulating matrix metalloproteinases, enhancing collagen synthesis, and promoting tissue regeneration and angiogenesis. Each chapter is backed by current research, offering mechanistic insights that bridge traditional knowledge with modern biomedical science. This structured and progressive organization ensures that all key aspects of polyphenol-based wound healing are clearly presented and easy to follow, making the book highly accessible for researchers, clinicians, and students alike.
This includes mechanisms such as reducing inflammation, combating oxidative stress, modulating matrix metalloproteinases, enhancing collagen synthesis, and promoting tissue regeneration and angiogenesis. Each chapter is backed by current research, offering mechanistic insights that bridge traditional knowledge with modern biomedical science. This structured and progressive organization ensures that all key aspects of polyphenol-based wound healing are clearly presented and easy to follow, making the book highly accessible for researchers, clinicians, and students alike.
Table of Contents
Section I Science of wound healing1. Overview of skin structure and its normal physiology
2. Types of wounds
3. Process of wound healing
4. Therapeutic targets of wound healing
Section II Polyphenols: Occurrence, techniques for isolation extraction and purification
5. Sources of polyphenols and their occurrence
6. Overview of medicinal plants rich in polyphenols
7. Techniques for extraction, isolation and purification of polyphenols from medicinal plants
Section III Polyphenols and their mechanisms in wound healing
8. Polyphenols and inflammation in wound healing
9. Polyphenols and oxidative stress in wound healing
10. Polyphenols and matrix metalloproteinase in wound healing
11. Polyphenols and collagen in wound healing
12. Polyphenols and tissue regeneration in wound healing
13. Polyphenols and angiogenesis in wound healing
Section IV Current trends of polyphenol-based drug development in wound healing
14. Polyphenol based products for wound healing
15. Challenges of using polyphenols for wound healing
16. Current trends of using polyphenols for wound healing
Authors
Bushra Akhtar Lecturer, Department of Pharmacy, Faculty of Health and Pharmaceutical Sciences, University of Agriculture, Faisalabad, Pakistan.Bushra Akhtar earned her Doctor of Philosophy (Pharmacology) degree from the University of Agriculture, Faisalabad, Pakistan. She studied Master of Philosophy (Pharmacology and Toxicology) from the University of Veterinary and Animal Sciences, Lahore, Pakistan. She did Pharm-D from Bahauddin Zakariya University, Multan, Pakistan. She is working as a lecturer in the Department of Pharmacy, Faculty of Health and Pharmaceutical Sciences, University of Agriculture, Faisalabad, Pakistan. She has published 60 peer-reviewed articles with an impact factor of around 160. She has one national patent to her credit. Dr. Bushra Akhtar has produced around 20 postgraduate students as the major supervisor. She is the editorial board member of 03 impact factor journals. She has done good work on polyphenols as well as wound healing and dermal drug absorption.
Ali Sharif Asst Professor, Department of Pharmacology, Institute of Pharmacy, Faculty of Pharmaceutical and Allied Health Sciences, Lahore College for Women University, Lahore, Pakistan. Ali Sharif is currently serving as an Assistant Professor at the Department of Pharmacology, Institute of Pharmacy, Faculty of Pharmaceutical and Allied Health Sciences, Lahore College for Women University, Lahore. He received his PhD in Pharmacology and Toxicology in 2016 at University of Veterinary and Animal Sciences, Lahore. He studied Master of Philosophy (Pharmaceutics) and BPharm from Bahauddin Zakariya University, Multan, Pakistan. He has teaching experience of more than 15 years. He has produced more than 25 MPhil and PhD students as the major supervisor. He is the author of more than 65 research papers and book chapters with a cumulative impact factor of 150. He is the editorial board member of 03 impact factor journals. He has done great work on polyphenols as well as their mechanistic insights for management of different diseases.
