Biopolymers for 3D Tissue Engineering. Processing and Applications

Biopolymers for 3D Tissue Engineering: Processing and Applications explores the critical role of biopolymers in advancing tissue engineering and 3D cell culture-key technologies in drug discovery, personalized medicine, and disease treatment. Scaffolds form the foundation of these applications, yet current options-primarily synthetic polymers like polypropylene, polyethylene, or polystyrene, and some natural materials such as collagen and silk fibroin-are often expensive and lack optimal properties such as biocompatibility, biodegradability, and mechanical stability. This book addresses the global effort to develop next-generation scaffolds that overcome these limitations. Biopolymers offer a compelling solution, with inherent biodegradability, biocompatibility, and sustainability. They are abundant, cost-effective, and derived from renewable sources, making them ideal for medical applications. However, their processing poses significant challenges, as many biopolymers resist dissolution in common solvents and lack thermoplastic behavior. This book provides a comprehensive overview of the structure, properties, and processability of biopolymers, with a focus on innovative techniques for converting them into functional scaffolds suitable for 3D cell culture. Unlike existing literature that emphasizes biomaterial properties or applications, this is the first book to focus exclusively on biopolymers for tissue engineering. It covers carbohydrates, proteins, and synthetic biopolymers in a single, authoritative source, making it invaluable for students, researchers, professionals, and industry stakeholders. By bridging the gap between material science and biomedical application, Biopolymers for 3D Tissue Engineering offers both a scientific foundation and practical insights to accelerate the development of sustainable, high-performance scaffolds for next-generation healthcare solutions.

Section I: Developing Biomaterials from Natural Polysaccharides
1. Developing biomaterials from plant cellulose
2. Bacteria cellulose as a source for 3D scaffolds for tissue engineering
3. Structure and properties of biomaterials from starch
4. Processing, properties and applications of biomaterials from chiosan
5. Potential of alginate as a source for 3D tissue engineering and cell culture
6. Miscellaneous polysaccharides for 3D scaffolds

Section II. Biomaterials from natural proteins
7. Developing biomaterials from collagen
8. Converting silk fibroin into 3D scaffolds for tissue engineering
9. Biomaterials from silk sericin
10. Keratin as a biomaterial for 3D cell culture and tissue engineering
11. Plant proteins for tissue engineering
12. Miscellaneous proteins used for tissue engineering

Section III. Biomaterials from synthetic biopolymers
13. Poly (lactic acid) based scaffolds for 3D cell culture
14. PHBV and other synthetic biopolymers

Authors

Narendra Reddy Professor for Incubation, Innovation, Research and Consultancy, Jyothy Institute of Technology, Bengaluru, India.

Narendra Reddy is a prominent researcher in the field of biopolymeric materials. He currently holds the position of Professor and Ramalingaswami fellow at the Center for Incubation Innovation Research and Consultancy. He obtained his doctoral degree from the University of Nebraska-Lincoln in USA in the year 2006. He has published about 175 research papers in high impact journals, five books and 12 book chapters. He also holds an US patent. His work has been reported by CNN, Discovery, Nature, American Chemical Society and other major news agencies. He was a recipient of the prestigious Ramalingaswami Fellowship from the Department of Biotechnology, Government of India. He has received funding for his research from DST, DBT and CEFIPRA (India-France joint funding). He is also the founder of a start-up "Agringenium Innovations Private Limited� which has been selected by Niti Aayog for funding through the Atal New India Challenge (ANIC).

Pornanong Aramwit Vice President, Research and Innovation, Chulalongkorn University, Bangkok, Thailand.

Pornanong Aramwit serves as the Vice President in Research and Innovation at Chulalongkorn University. Dr. Aramwit's research has covered protein research, including silk proteins, biomaterials, tissue engineering, and herbal substances. She has conducted clinical studies in nephrology and has been researching dermatology, focusing on materials for wound healing applications. She is an inventor in medical devices and has received awards including the Merits of Leadership Award Grand Officer Level from the UK, France, and Belgium, as well as from the European Union and Spain. She was awarded the 2018 Ambassador Award for Innovator with Outstanding Achievements, the 2019 Outstanding Professional Women Award by the Federation of Business and Professional Women of Thailand, and the 2024 National Outstanding Researcher Award by the National Research Council of Thailand. She's authored over 220 peer-reviewed articles, authored/co-authored several books and book chapters, and has 20 patents.

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