Gain the in-depth understanding of pathophysiology you need to guide your patient care! Using a systems approach, Pathophysiology, 8th Edition, examines the etiology, pathogenesis, clinical manifestations, and treatment of diseases and disorders. The book begins with a review of normal anatomy and physiology, followed by pathophysiology and application of concepts to specific disorders. Each chapter includes a discussion of the disease processes and abnormalities that may occur, with a focus on the pathophysiologic concepts involved. Written by a team of expert contributors led by Jacquelyn Banasik, this text emphasizes the major pathophysiology concepts relevant to clinical practice while not overwhelming the reader with minute detail.
- Clear, easy-to-read writing style emphasizes critical thinking, and includes many tables, boxes, and figures to highlight key content
- Thorough updates include information on the newest scientific findings and advances in treatment, more than 100 new figures for improved clarity, and more
- More than 1,000 full-color photos and illustrations help to clarify complex pathophysiological concepts
- Global Health Care boxes summarize topics such as COVID-19, HIV/AIDS, Ebola, tropical diseases, and more, with information on prevalence, mechanism of disease and transmission
- Pediatric and Older Adult Considerations boxes address age-related changes associated with specific body systems
- Useful learning resources include chapter outlines, bolded key terms, key questions, Key Points boxes, Clinical Judgment challenges, and chapter summaries
- NEW! Updated content throughout the book reflects the latest research and thinking in pathophysiology
Table of Contents
UNIT I Pathophysiologic Processes1 Introduction to Pathophysiology
2 Homeostasis Allostasis and Adaptive Responses to Stressors
UNIT II Cellular Function
3 Cell Structure and Function
4 Cell Injury Aging and Death
5 Genome Structure Regulation and Tissue Differentiation
6 Genetic and Developmental Disorders
7 Neoplasia
UNIT III Defense
8 Infectious Processes
9 Inflammation and Immunity
10 Alterations in Immune Function
11 Malignant Disorders of White Blood Cells
12 HIV Disease and Aids
UNIT IV Oxygen Transport Blood Coagulation Blood Flow and Blood Pressure
13 Alterations in Oxygen Transport
14 Alterations in Hemostasis and Blood Coagulation
15 Alterations in Blood Flow
16 Alterations in Blood Pressure
UNIT V Cardiac Function
17 Cardiac Function
18 Alterations in Cardiac Function
19 Heart Failure and Dysrhythmias
20 Shock
UNIT VI Respiratory Function
21 Respiratory Function and Alterations in Gas Exchange
22 Obstructive Pulmonary Disorders
23 Restrictive Pulmonary Disorders
UNIT VII Fluid Electrolyte and Acid-Base Homeostasis
24 Fluid and Electrolyte Homeostasis and Imbalances
25 Acid-Base Homeostasis and Imbalances
UNIT VIII Renal and Bladder Function
26 Renal Function
27 Intrarenal Disorders
28 Acute Kidney Injury and Chronic Kidney Disease
29 Disorders of the Lower Urinary Tract
UNIT IX Genital and Reproductive Function
31 Alterations in Male Genital and Reproductive Function
32 Female Genital and Reproductive Function
33 Alterations in Female Genital and Reproductive Function
34 Sexually Transmitted Infections
UNIT X Gastrointestinal Function
36 Gastrointestinal Disorders
37 Alterations in Function of the Gallbladder and Exocrine Pancreas
38 Liver Diseases
UNIT XI Endocrine Function Metabolism and Nutrition
39 Endocrine Physiology and Mechanisms of Hypothalamic Pituitary Regulation
40 Disorders of Endocrine Function
41 Diabetes Mellitus
42 Alterations in Metabolism and Nutrition
UNIT XII Neural Function
43 Structure and Function of the Nervous System
44 Acute Disorders of Brain Function
45 Chronic Disorders of Neurologic Function
46 Alterations in Special Sensory Function
47 Pain
UNIT XIII Neuropsychological Function
48 Mental Health Disorders
UNIT XIV Musculoskeletal Support and Movement
49 Structure and Function of the Musculoskeletal System
50 Alterations in Musculoskeletal Function Trauma Infection and Disease
51 Alterations in Musculoskeletal Function Rheumatic Disorders
UNIT XV Integumentary System
52 Alterations in the Integumentary System
53 Burn Injuries
