As the number of immunocompromised pediatric patients increases year by year, the need for authoritative guidance, clinically actionable strategies, and easy-to-find information in this challenging area also continues to grow. Infectious Diseases in the Immunocompromised Child, 2nd Edition (formerly Pediatric Transplant and Oncology Infectious Diseases), provides up-to-date, targeted coverage of this complex field, compiled by world-renowned editors and authors into one convenient volume. An essential resource for infectious diseases physicians and others who care for pediatric patients undergoing transplant, cancer care, or treatment of dysregulated immunity, this newly expanded reference keeps you at the forefront of knowledge for these therapies so that you can anticipate the infectious presentations that often arise from them.
- Covers the must-know principles for diagnosing and managing opportunistic infections in immunocompromised populations and detailed aspects of their care-information not specifically covered in other books
- Provides authoritative coverage in a one-of-a kind compilation that reflects recent advances in hematopoietic cell and solid organ transplantation, as well as evolving chemotherapeutic regimens and immunomodulation therapies
- Focuses on practical, clinically actionable, and easy-to-find information, providing numerous figures, tables, and treatment algorithms for ease of use and significantly more images than the previous edition
- Covers an evolving immunocompromised patient population receiving novel immunomodulators, such as those with underlying rheumatological and autoinflammatory conditions, and discusses key topics such as microbiome implications in transplantation and oncology, antimicrobial resistant Gram-negative bacteria, EBV-associated post-transplant lymphoproliferative disorders, and many others
- Offers the insights and expertise of worldwide contributing authors-expert investigators and clinicians who are actively deciphering the mechanisms of disease and developing the latest approaches to optimal pediatric care
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date
Table of Contents
SECTION 1 General Immunocompromised Host Infection Principles1. The Surgical and Immunosuppressive Basis for Infections in the Pediatric Solid Organ Transplant Recipient
2. Immunologic Recovery and Basis for Infections in the Pediatric Hematopoietic Stem Cell Transplant Recipient
3. Cancer and Antineoplastic Therapies and the Risk of Infection in the Pediatric Cancer Patient
4. Infections in Pediatric Patients with Underlying Illness
SECTION 2 Common Immunocompromised Host Infection Situations
5. Infectious Disease Evaluation of Infants and Children Awaiting Solid Organ or Hematopoietic Stem Cell Transplant
6. Donor Screening and Donor-Derived Infections
7. Prevention of Infections in the Hematopoietic Stem Cell Transplant Recipient
8. Prevention of Infections in the Solid Organ Transplantation Recipient
9. Management Principles for Patients with Neutropenia
10. Vaccination Issues for Immunocompromised Patients
11. Microbiome Implications in Immunocompromised Patients
12. Antimicrobial Stewardship in Immunocompromised Hosts
13. Hospital Infection Prevention for Immunocompromised Patients
14. Safe Living After Transplantation, Chemotherapy, or other Illness
SECTION 3 Specific Infections in Immunocompromised Patients
15. Multidrug-Resistant Gram-Negative Infections in Immunocompromised Patients
16. Bartonella, Legionella, Mycoplasma, and Ureaplasma
17. Nontuberculous and Tuberculous Mycobacterium
18. Cytomegalovirus
19. Epstein-Barr Virus and Posttransplant Lymphoproliferative Disorder
20. Herpes Simplex and Varicella-Zoster Viruses
21. Human Herpesvirus 6, 7, and 8
22. Respiratory Viruses
23. Adenoviruses
24. BK and Other Polyomavirus Associated Diseases in Children
25. Aspergillosis
26. Mucormycosis, Fusariosis, Scedosporiasis, and Other Invasive Mold Diseases
27. Candidiasis
28. Cryptococcosis and Other Rare Invasive Yeast Infections
29. Histoplasmosis, Blastomycosis, and Coccidioidomycosis
30. Toxoplasma gondii
31. Nocardia and Actinomyces
32. Pneumocystis Pneumonia
33. Strongyloides, Cryptosporidium, and Other Parasitic Infections
34. Gastrointestinal Viruses
35. Clostridioides difficile Infection
