North America Collagen Market Size and Forecast (2021 - 2031)

The North America Collagen Market is projected to grow significantly, reaching an estimated US$ 2,458.8 million by 2031, up from US$ 1,767.5 million in 2024. This growth represents a compound annual growth rate (CAGR) of 4.8% from 2025 to 2031, driven primarily by the expanding pharmaceutical sector in the region.

Executive Summary and Market Analysis

The pharmaceutical industry in North America is a key driver of the collagen market. According to IQVIA, North America accounted for 53.3% of global pharmaceutical sales in 2023, with the United States alone responsible for 67.1% of new medicine sales launched between 2018 and 2023. Collagen is increasingly recognized for its essential role in health and nutritional supplements, serving as a fundamental building block for connective tissues and overall health. Hydrolyzed collagen, in particular, is widely utilized in health supplements, promoting the health of muscles, skin, bones, and connective tissues.

In response to rising consumer awareness regarding the health benefits of collagen, numerous regional nutrition and healthcare companies have introduced collagen supplement formulations. For example, in November 2023, Designs for Health, Inc., a health supplement manufacturer operating in the US, Canada, and Australia, launched two new products: Collagen + MCT and Whole Beauty Collagen, both featuring hydrolyzed collagen peptides. This trend reflects the growing demand for collagen products in North America, fueled by the pharmaceutical industry's expansion and increasing consumer knowledge of collagen's benefits.

Strategic Insights

Market Segmentation Analysis

The North America Collagen Market can be segmented by product type, source, and application:

• By Product Type: The market is divided into Gelatin, Hydrolyzed Collagen, Native Collagen, Synthetic Collagen, and Others. In 2024, the Gelatin segment was the market leader.
• By Source: The market is categorized into Bovine, Porcine, Poultry, Marine, and Others, with the Bovine segment dominating in 2024.
• By Application: The applications include Food and Beverages, Pharmaceuticals and Nutraceuticals, Personal Care and Cosmetics, Animal Nutrition, Healthcare, and Others. The Pharmaceuticals and Nutraceuticals segment was the largest in 2024.

Market Outlook

Collagen is a vital structural protein utilized across various industries due to its unique properties, including biocompatibility, biodegradability, and its ability to support tissue regeneration and cellular repair. In regenerative medicine, collagen is crucial for wound healing, bone regeneration, and tissue engineering. For instance, in January 2025, Humabiologics, a biotechnology firm, received funding to advance the biomanufacturing of the first human-derived collagen matrix for regenerative applications. This innovation is expected to enhance the use of collagen in tissue engineering and cell therapy, particularly in sensitive human applications where xenogeneic materials may pose risks. Human collagen matrices provide improved biocompatibility and reduced immune rejection, paving the way for advancements in orthopedics, neurology, and reconstructive surgery.

Additionally, in September 2024, Orthocell launched Striate+, a collagen membrane product for dental regeneration, which received regulatory approval in Canada. This product supports dental-guided bone and tissue regeneration, providing a robust barrier that aids in the regeneration of bone and soft tissue around implant sites. As dental procedures become more advanced, the demand for collagen-based scaffolds and membranes is expected to rise significantly.

In May 2025, Holista CollTech announced its focus on nano-collagen applications in cosmetics and personal care. The use of nano-sized collagen particles allows for deeper skin penetration and enhanced efficacy in anti-aging and skin-repair formulations, catering to the growing consumer demand for non-invasive, scientifically-backed skincare solutions. Furthermore, in February 2024, Evonik partnered with Jland Biotech to commercialize vegan collagens, reflecting a shift towards cruelty-free and sustainable products. Vegan collagen, produced through fermentation and precision biomanufacturing, is set to replace animal-derived sources in supplements, foods, and cosmetics, aligning with the increasing popularity of plant-based lifestyles.

The diverse applications of collagen in biomedical devices, cosmetic products, regenerative therapies, and functional foods and beverages have created a robust demand. Moreover, advancements in collagen sourcing and delivery systems are significantly contributing to the growth of the North America collagen market.

Country Insights

The North America Collagen Market is segmented by country into the United States, Canada, and Mexico, with the United States holding the largest market share in 2024. Increased health awareness among consumers in the US, driven by the high prevalence of chronic diseases such as diabetes, has spurred demand for health supplements and nutritional drinks. As of November 2023, over 37 million Americans were diagnosed with Type 1 or Type 2 diabetes, prompting a surge in interest in collagen's health benefits, including its potential to improve insulin sensitivity and stabilize blood sugar levels. For instance, Glanbia PLC expanded its product line through ISOPURE with collagen peptides that support hair, joint, nail, and skin health, as well as immune function. This growing health consciousness among consumers is a significant factor driving the collagen market's growth in the United States.

Company Profiles

Key players in the North America Collagen Market include Darling Ingredients Inc, GELITA AG, Holista CollTech Ltd, Weishardt Holding SA, Tessenderlo Group NV, Titan Biotech Ltd, Viscofan SA, ConnOils LLC, Lapi Gelatine SpA, Nippi Inc, Nitta Gelatin Inc, Ewald-Gelatine GmbH, CNABIOTECH Co Ltd, DCP Ingredients (DCP BV), and Foodmate Co Ltd. These companies are employing various strategies, including expansion, product innovation, and mergers and acquisitions, to enhance their product offerings and increase market share.