The global aneurysm clip market was valued at $59 million in 2025. The market is expected to decline at a compound annual growth rate (CAGR) of -0.7%, reaching $56 million by 2032.
This report covers the global market for aneurysm clips, segmented by material type into titanium and cobalt alloy, and by device modality into temporary and permanent. The report quantifies procedure numbers, unit sales, average selling prices (ASPs), market values, growth rates, and company shares, with historical data back to 2022 and forecasts through 2032.
Unit sales in the global aneurysm clip market are expected to gradually decline over the forecast period, reflecting a structural shift toward minimally invasive endovascular alternatives to surgical clipping. ASPs are also trending downward due to pricing pressures and market maturity. Together, these factors contribute to a modest but consistent contraction in overall market value through 2032.
Clipping retains procedural relevance in specific clinical scenarios where aneurysm morphology, location, and patient characteristics make endovascular approaches less suitable. Wide-necked aneurysms, anatomically favorable surgical sites, and cases involving multiple aneurysms reachable through a single craniotomy remain areas where clipping is preferred, providing a stable procedural floor that limits the pace of overall market decline.
The shift toward endovascular neurovascular techniques has been the dominant force reshaping this market. Coiling and catheter-based approaches are minimally invasive, require no craniotomy, and significantly reduce hospital length of stay compared to surgical clipping. For the majority of aneurysm locations and morphologies, endovascular treatment has become the preferred first-line approach. As clinical experience with endovascular techniques has broadened and physician training has expanded, the number of aneurysm cases directed toward clipping has steadily narrowed.
Clipping retains a defined clinical role in specific cases where endovascular approaches are less suitable. Wide-necked aneurysms with a dome-to-neck ratio below 1.5, middle cerebral artery aneurysms where surgical access is favorable, and cases involving multiple aneurysms accessible through a single craniotomy are settings where clipping continues to be preferred. Long-term data from the ISAT trial also showed that coiling carries a higher re-hemorrhage rate compared to clipping, supporting continued use of surgical clips in younger patients where the permanence of the repair has long-term clinical value.
Newer intrasaccular devices are adding further competitive pressure in indications that were historically considered clip-preferred. The WEB aneurysm embolization system, which redirects blood away from the aneurysm to promote clotting, is primarily indicated for large or giant wide-necked brain aneurysms that were once among the strongest candidates for surgical clipping. As this and competing devices build clinical track records and expand approved indications, the proportion of cases where clipping is the only viable option continues to narrow, contributing to the market's ongoing contraction.
B. Braun held the second-leading position in the aneurysm clip market in 2025. The company offers the Yasargil aneurysm clip line, which is MRI-safe and non-ferromagnetic, available in two material options: Phynox (a cobalt chrome alloy) and titanium. MRI compatibility is a clinically important product attribute, as it allows patients to undergo post-operative neurological imaging without restrictions associated with ferromagnetic implants. The Yasargil clip carries significant clinical heritage and established physician familiarity, which supports sustained market presence in a segment where long-established product trust influences purchasing decisions.
Peter Lazic was the third-leading and newest competitor in the global aneurysm clip market in 2025. The company offers approximately 220 different aneurysm clip variants made from titanium alloys, providing one of the broadest product ranges in the segment in terms of clip geometry and configuration. The company is also experimenting with PEEK (polyether ether ketone), an MRI-safe plastic material, as a potential future direction for clip construction. This positions Peter Lazic as an innovator within a declining market, with PEEK's material properties and MRI compatibility representing a differentiated development direction relative to established metal clip suppliers.
5 charts and 40 figures illustrating market segmentation and performance metrics.
Methodology Appendix, Abbreviation and Acronym Glossary explaining all data definitions and modeling assumptions.
Licensing options: single-user, site, and enterprise.
This report covers the global market for aneurysm clips, segmented by material type into titanium and cobalt alloy, and by device modality into temporary and permanent. The report quantifies procedure numbers, unit sales, average selling prices (ASPs), market values, growth rates, and company shares, with historical data back to 2022 and forecasts through 2032.
Unit sales in the global aneurysm clip market are expected to gradually decline over the forecast period, reflecting a structural shift toward minimally invasive endovascular alternatives to surgical clipping. ASPs are also trending downward due to pricing pressures and market maturity. Together, these factors contribute to a modest but consistent contraction in overall market value through 2032.
Clipping retains procedural relevance in specific clinical scenarios where aneurysm morphology, location, and patient characteristics make endovascular approaches less suitable. Wide-necked aneurysms, anatomically favorable surgical sites, and cases involving multiple aneurysms reachable through a single craniotomy remain areas where clipping is preferred, providing a stable procedural floor that limits the pace of overall market decline.
Market Overview
The global aneurysm clip market is a mature and gradually contracting segment within the broader neurovascular device space. Aneurysm clipping, which requires a craniotomy to provide direct surgical access to the aneurysm, was once the primary treatment for intracranial aneurysms. Over the past two decades, the growth of endovascular coiling and the introduction of increasingly capable intrasaccular devices have substantially reduced the volume of clipping procedures performed globally. The -0.7% CAGR over the forecast period reflects a market in managed decline rather than acute contraction, with a persistent procedural base maintained by specific anatomical indications that continue to favor the surgical approach.The shift toward endovascular neurovascular techniques has been the dominant force reshaping this market. Coiling and catheter-based approaches are minimally invasive, require no craniotomy, and significantly reduce hospital length of stay compared to surgical clipping. For the majority of aneurysm locations and morphologies, endovascular treatment has become the preferred first-line approach. As clinical experience with endovascular techniques has broadened and physician training has expanded, the number of aneurysm cases directed toward clipping has steadily narrowed.
Clipping retains a defined clinical role in specific cases where endovascular approaches are less suitable. Wide-necked aneurysms with a dome-to-neck ratio below 1.5, middle cerebral artery aneurysms where surgical access is favorable, and cases involving multiple aneurysms accessible through a single craniotomy are settings where clipping continues to be preferred. Long-term data from the ISAT trial also showed that coiling carries a higher re-hemorrhage rate compared to clipping, supporting continued use of surgical clips in younger patients where the permanence of the repair has long-term clinical value.
Newer intrasaccular devices are adding further competitive pressure in indications that were historically considered clip-preferred. The WEB aneurysm embolization system, which redirects blood away from the aneurysm to promote clotting, is primarily indicated for large or giant wide-necked brain aneurysms that were once among the strongest candidates for surgical clipping. As this and competing devices build clinical track records and expand approved indications, the proportion of cases where clipping is the only viable option continues to narrow, contributing to the market's ongoing contraction.
Market Drivers
Aneurysm Morphology and Location
Despite the overall decline in clipping procedures, a significant number of cases will continue to be treated with aneurysm clips because of morphological and anatomical characteristics that make endovascular approaches less suitable. Clipping is preferred for wide-necked aneurysms or those with a dome-to-neck ratio below 1.5, where maintaining coil stability within the aneurysm sac is difficult. When multiple aneurysms can be accessed through a single craniotomy, clipping is also the preferred approach as it allows treatment of multiple lesions in a single surgical session. Middle cerebral artery aneurysms in particular tend to be clipped due to the relative ease of surgical access in that location. These morphological indications are not expected to disappear, providing a stable procedural base that limits the overall pace of market decline, even as endovascular alternatives capture an increasing share of eligible cases.Long-Term Efficacy of Permanent Clipping
The permanence of aneurysm clipping is a meaningful clinical advantage in specific patient populations. Complications associated with endovascular treatment, including coil compaction, coil migration, and the need for retreatment or shunt replacement, are not concerns with permanent surgical clipping. Long-term data from the ISAT trial found that coiling was associated with a higher rate of re-hemorrhage compared to clipping, which informs treatment decisions in favor of clipping for younger patients where the durability of the repair over many decades is a priority. This long-term efficacy argument ensures that aneurysm clips remain part of the neurosurgical treatment decision process even as endovascular approaches dominate aggregate procedure volumes globally.Market Limiters
Minimally Invasive Endovascular Techniques
The trend toward endovascular neurovascular treatment for intracranial aneurysms has made substantial progress over the past twenty years and continues to strengthen. Endovascular approaches are minimally invasive and significantly reduce patient hospital length of stay compared to aneurysm clipping, which requires a craniotomy. For the majority of patients and aneurysm presentations, the reduced procedural invasiveness and faster recovery associated with coiling or intrasaccular device treatment outweigh the long-term efficacy advantages of clipping. As physician training in endovascular techniques continues to expand and clinical outcomes data continues to support minimally invasive approaches across a broadening range of indications, the volume of clipping procedures is expected to continue its gradual decline throughout the forecast period.Introduction of New Technology
Newer intrasaccular devices are specifically displacing aneurysm clips in cases where wide-necked and complex aneurysms were historically among the most common indications for surgical clipping. The WEB aneurysm embolization system, which received FDA premarket approval in January 2019, has found commercial success in treating large or giant wide-necked brain aneurysms without the need for open surgery. Cerus Endovascular has also initiated clinical trials for a device designed to compete directly with the WEB system, indicating that further development in intrasaccular embolization technology is underway. As these devices expand their clinical evidence base and approved indications, they are expected to capture additional procedural share from surgical clipping and contribute to the ongoing contraction of the aneurysm clip market.Market Coverage and Data Scope
- Quantitative coverage: Procedure numbers, market size, market shares, market forecasts, growth rates, units sold, and average selling prices.
- Qualitative coverage: Growth trends, market limiters, competitive analysis and SWOT for top competitors, mergers and acquisitions, company profiles and product portfolios, and technology trends shaping demand.
- Time frame: Base year 2025, forecasts 2026 to 2032, historical data 2022 to 2024.
- Data sources: Primary interviews with neurovascular device industry leaders and neurosurgeons, regulatory data, hospital procurement data, import and export data, and the iData Research internal database.
- Care settings: Hospitals and neurosurgical specialty centers.
Markets Covered and Segmentation
The aneurysm clip market is analyzed across two segmentation dimensions, each assessed by procedure volume, unit volume, ASP, and market value with historical and forecast data:
Material Type:
- Titanium Clips
- Cobalt Alloy Clips
Device Modality:
- Temporary Clips
- Permanent Clips
Competitive Analysis
Mizuho was the leader in the global aneurysm clip market in 2025. The company's Sugita Titanium 2 aneurysm clip features an ultra-slim profile designed to improve handling and provide a clearer surgical sightline during the clipping procedure. This design characteristic is particularly valuable in the confined operating environment of a neurosurgical craniotomy, where visualization and instrument maneuverability directly influence procedural safety and outcomes. Mizuho's specialized focus on neurosurgical instrumentation supports its leadership in a segment where clinical heritage and product reliability are primary purchasing criteria for neurosurgeons.B. Braun held the second-leading position in the aneurysm clip market in 2025. The company offers the Yasargil aneurysm clip line, which is MRI-safe and non-ferromagnetic, available in two material options: Phynox (a cobalt chrome alloy) and titanium. MRI compatibility is a clinically important product attribute, as it allows patients to undergo post-operative neurological imaging without restrictions associated with ferromagnetic implants. The Yasargil clip carries significant clinical heritage and established physician familiarity, which supports sustained market presence in a segment where long-established product trust influences purchasing decisions.
Peter Lazic was the third-leading and newest competitor in the global aneurysm clip market in 2025. The company offers approximately 220 different aneurysm clip variants made from titanium alloys, providing one of the broadest product ranges in the segment in terms of clip geometry and configuration. The company is also experimenting with PEEK (polyether ether ketone), an MRI-safe plastic material, as a potential future direction for clip construction. This positions Peter Lazic as an innovator within a declining market, with PEEK's material properties and MRI compatibility representing a differentiated development direction relative to established metal clip suppliers.
Technology and Practice Trends
- Ultra-slim clip profiles: Low-profile clip designs improve surgeon sightlines and instrument handling during craniotomy procedures, where precision in a confined operative space is critical to safe and effective aneurysm occlusion.
- MRI-compatible materials: Both titanium and Phynox cobalt chrome alloy clips provide MRI safety for post-operative neurological imaging, and PEEK experimentation signals a potential future direction for non-metallic clip materials with similar imaging compatibility.
- PEEK clip development: Peter Lazic's exploration of PEEK as a clip material represents an emerging innovation direction that could differentiate future products in a market where imaging compatibility and material performance are key clinical considerations.
- Intrasaccular device displacement: The WEB system and competing intrasaccular devices for wide-necked aneurysms are directly displacing clipping in cases that were historically among the strongest surgical candidates, narrowing the clip market's addressable procedural base.
- Long-term outcomes evidence: ISAT data on re-hemorrhage rates following coiling versus clipping continues to inform treatment decisions for younger patients, maintaining the clinical rationale for clipping in cases where long-term repair durability is prioritized.
- Morphology-driven case selection: Increasing precision in defining which aneurysm morphologies and locations favor clipping over endovascular alternatives is concentrating clip use in the cases where surgical advantages are clinically clearest.
Geography
This report provides global coverage across North America, Europe, Asia-Pacific, Latin America, the Middle East, and Africa.Deliverables
75 pages of detailed narrative analysis, tables, and figures.5 charts and 40 figures illustrating market segmentation and performance metrics.
Methodology Appendix, Abbreviation and Acronym Glossary explaining all data definitions and modeling assumptions.
Licensing options: single-user, site, and enterprise.
Why This Report
- What is the size and expected trajectory of the global aneurysm clip market through 2032, and which forces are driving the pace and character of its decline?
- Which aneurysm morphologies, dome-to-neck ratios, and anatomical locations continue to favor surgical clipping over endovascular alternatives, and how large is this residual procedural base?
- How are intrasaccular devices such as the WEB system displacing clip procedures in wide-necked aneurysm cases that were historically among the strongest surgical candidates?
- What is the commercial impact of long-term ISAT re-hemorrhage data on physician preference for clipping in younger patient populations?
- How are material innovations including PEEK clip development positioned to differentiate products within a declining but clinically persistent market?
- Which companies lead the market and how do they differentiate their clip portfolios through material type, MRI compatibility, and clip geometry range?
- What is the outlook for titanium versus cobalt alloy clips, and for temporary versus permanent device modalities, over the forecast period?
- What are the key risks to market stability, including further intrasaccular device adoption, expanding endovascular indications, and continued ASP erosion?
Table of Contents
Research Methodology
Aneurysm Clip Market
List of Charts
List of Figures
