The continuing burden of pressure injuries is increasing demand for effective wound-care and treatment solutions across U.S. healthcare settings. For instance, AHRQ Network of Patient Safety Databases Chartbook, 93,807 pressure injury events were reported through December 2024. Among the 17,077 events with valid information on the most advanced stage, 66.6% (11,377 cases) were deep tissue pressure injuries, 10.2% (1,748 cases) were Stage 3, and approximately 21.1% (3,600 cases) were unstageable. The report also found that 77.1% of 17,936 reported events involved patients who had received a preventive intervention, indicating that pressure injuries continue to occur despite preventive measures. Furthermore, 63.8% of reported cases developed a secondary morbidity or had an unknown outcome, while Stage 4 injuries showed the highest reported harm rate at 82%. The substantial number of advanced and potentially harmful pressure injuries supports continued demand for advanced dressings, negative pressure wound therapy, pressure-relieving systems, and other treatment solutions.
Clinical Trials Landscape
Clinical trials are supporting innovation in the U.S. pressure ulcer treatment market by generating clinical evidence on advanced biological therapies for severe and nonhealing wounds. Research is focused on cellular, acellular, and matrix-like products that can accelerate wound closure and improve outcomes in patients with difficult-to-heal Stage III and Stage IV pressure ulcers. For instance, in May 2025, Tiger Biosciences, LLC initiated the Phase 4 NCT06999590 clinical trial in the U.S. to evaluate several cellular, acellular, and matrix-like products (CAMPs), including ACApatch and caregraFT, in combination with standard wound care for nonhealing pressure ulcers. The multicenter, prospective, randomized controlled modified platform trial plans to enroll approximately 500 adult patients with chronic Stage III or Stage IV pressure ulcers. The study will compare weekly applications of these biological products plus standard care with matched standard-of-care controls, with complete wound closure serving as the primary outcome. The trial is expected to be completed in May 2027. The study highlights the growing development of advanced biological and regenerative wound-care therapies and is expected to strengthen clinical evidence supporting the adoption of active & bio-therapies, particularly cellular, acellular, and matrix-based products, in the U.S. pressure ulcer treatment market.U.S. Pressure Ulcer Treatment Market Report Segmentation
This report forecasts revenue growth at country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, the analyst has segmented the U.S. pressure ulcer treatment market report based on product, clinical severity, and end use:Product Outlook (Revenue, USD Million, 2021 - 2033)
- Wound Care Dressings
- Moist
- Foam Dressings
- Hydrocolloid Dressings
- Film Dressings
- Alginate Dressings
- Hydrogel Dressings
- Collagen Dressings
- Other Advanced Dressing
- Antimicrobials
- Silver
- Non-silver
- Active & Bio-Therapies
- Active Biomaterials
- Bioengineered Skin Substitutes
- Growth Factors
- Wound Care Devices & Systems
- Negative Pressure Wound Therapy (NPWT)
- Pressure Redistribution & Support Surfaces
- Hyperbaric Oxygen Equipment
- Electrical Stimulation Devices
- Topical & Pharmacological Agents
- Debriding Agents
- Topical Antimicrobials & Antiseptics
- Other Treatment Products
- Offloading & Positioning Devices
- Wound Cleansing & Irrigation Products
Clinical Severity Outlook (Revenue, USD Million, 2021 - 2033)
- Stage I
- Stage II
- Stage III
- Stage IV
- Deep Tissue Injury (DTI)
End Use Outlook (Revenue, USD Million, 2021 - 2033)
- Acute Care Hospital
- Long-term Acute Care Hospital
- Burn Center
- Ambulatory Surgery Center
- Hospital Outpatient Department Wound Care Clinic
- Inpatient Rehabilitation Facility
- Skilled Nursing Facility
- Long-term Care (living setting)
- Physician Office
- Home Healthcare
Why should you buy this report?
- Comprehensive Market Analysis: Gain detailed insights into the market across major regions and segments.
- Competitive Landscape: Explore the market presence of key players.
- Future Trends: Discover the pivotal trends and drivers shaping the future of the market.
- Actionable Recommendations: Utilize insights to uncover new revenue streams and guide strategic business decisions.
This report addresses:
- Market intelligence to enable effective decision-making
- Market estimates and forecasts from 2018 to 2030
- Growth opportunities and trend analyses
- Segment and regional revenue forecasts for market assessment
- Competition strategy and market share analysis
- Product innovation listing for you to stay ahead of the curve
Table of Contents
Companies Mentioned
- SYST'AM
- Ulcer Solutions, LLC.
- Stryker
- Baxter (Hillrom)
- Arjo
- LINET
- Invacare Corporation
- 3M
- Smith+Nephew
- Mölnlycke AB
- Savaria
- Joerns Healthcare
- B. Braun SE
- Medline
- Convatec
- BioLab Holdings, Inc.

