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Chromatography: A Research Outlook

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    Report

  • 126 Pages
  • September 2018
  • Region: Global
  • BCC Research
  • ID: 4650656
UP TO OFF until Aug 31st 2033

Chromatography technique, as a separation method, plays an important role in the fields of pharmaceutical, biotechnology, environment, clinics, forensics and research, etc., for quantitative and qualitative analysis of raw materials, drug substances, drug products and chemical compounds in biological fluids. The report examines the overall chromatography reagents industry and the types of technologies currently in use as well as planned technological developments, end-user markets and regional distribution, in addition to the regulatory aspects and patents currently filed.

This report provides an overview of the current and forthcoming characteristics of the global market for the chromatography reagents market. The chromatography reagents covered in this report include solvents, buffers, adsorbents, derivatives (silyl derivatives, alkylation reagents, acylation reagents) and resins. The types of chromatography included in this report are gas chromatography, liquid chromatography, thin layer chromatography, affinity chromatography, ion exchange chromatography, size-exclusion chromatography, affinity chromatography, partition chromatography and others (capillary electrophoresis, solid phase extraction, and hyphenated approaches).

The market estimations are provided for the following chromatographic techniques: liquid, gas, ion exchange, size exclusion, thin layer, capillary electrophoresis, supercritical fluid and adsorption. The classifications, comparisons and usage of these types of separation techniques are also portrayed in this report. Liquid chromatography is further categorized into high-performance liquid chromatography, reverse phase chromatography, supercritical fluid chromatography and fast protein liquid chromatography. Ion exchange chromatography is categorized into cation chromatography and anion chromatography; and gas chromatography into headspace gas chromatography.

Revenues of chromatography reagents used in different chromatographic techniques are broken down by global region focusing on North America, Europe, and emerging markets in Asia-Pacific and South America. End users of chromatography techniques and reagents are discussed separately in the report, with an emphasis of the usage in biopharmaceuticals and pharmaceuticals; food and beverages; environment; clinics and forensics; petrochemicals/chemicals; and others (including academic and research institutes). The report additionally covers significant patents with respective filed and published dates along with their assignees. Acquisition strategies and collaborations by companies are also covered in this report.

The Report Includes:


  • 43 data tables and 45 additional tables
  • An overview of the global market for the chromatography reagents within the industry
  • Analyses of global market trends, with data from 2017, estimates for 2018 and projections of compound annual growth rates (CAGRs) through 2023
  • Quantification of the market for chromatography reagents by reagent type, technology, end use application, and geographical region
  • A look into the recent advancements and innovations in the form of cutting-edge technologies, available in the chromatography reagents market
  • Assessment of market dynamics, such as drivers and restraints that have an impact on the market.
  • Exploration of chromatography reagents, including solvents, buffers, adsorbents and derivatives
  • Coverage of significant patents with respective filed and published dates along with their assignees
  • Evaluation of the competitive landscape, and detailed profiles of major market players including Agilent Technologies, Bio-Rad Laboratories, Danaher Corp., Honeywell Burdick & Jackson (B&J), Sigma-Aldrich and Thermo Fisher Scientific, Inc.

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Table of Contents

Chapter 1 Introduction
  • Study Goals and Objectives
  • Reasons for Doing This Study
  • Scope of Report
  • Methodology and Information Sources
  • Geographic Breakdown
  • Analyst's Credentials
  • Custom Research
  • Related Reports



Chapter 2 Summary and Highlights
Chapter 3 Market and Technology Background
  • Introduction to Chromatography
  • Definitions
  • Uses of Chromatography
  • History of Chromatography
  • Classification of Chromatography
  • Applications of Chromatography
  • Factors Driving the Market
  • Rise in Government Investments
  • Increasing Demand of Chromatography Reagents
  • Innovations in the Field of Chromatography
  • Factors Restraining the Market
  • Presence of a Number of Alternative Techniques
  • High Cost of Chromatography Reagents
  • Regulatory Aspects of Chromatographic Reagents
  • Acetone
  • Chloroform
  • Benzene
  • Methanol
  • Phenol
  • Pyridine
  • Toluene
  • 1,2,3 Trichloropropane
  • Methylene Chloride
  • 2-Butanone (Methyl Ethyl Ketone)



Chapter 4 Reagents Used in Chromatography
  • Types of Reagents
  • Solvents
  • Buffers
  • Adsorbents
  • Derivatives
  • Industry Structure for Reagents of Chromatography
  • Gas Chromatography
  • Liquid Chromatography (LC) and Flash Chromatography
  • Thin Layer Chromatography (TLC)
  • Affinity Chromatography
  • Ion Exchange Chromatography
  • Size Exclusion Gel Permeation Chromatography
  • Cell Electrophoresis
  • Supercritical Fluid Chromatography



Chapter 5 Chromatography Reagents Market by Technique
  • Gas Chromatography
  • Headspace GC
  • Market for Reagents Used in Chromatography
  • Applications of Gas Chromatography
  • Liquid Chromatography
  • Reverse Phase Chromatography
  • High Performance Liquid Chromatography
  • Ultra-High-Performance Liquid Chromatography (UHPLC)
  • Fast Protein Liquid Chromatography
  • Market for Reagents Used in HPLC
  • Market Share
  • Applications of HPLC
  • Supercritical Fluid Chromatography
  • Column Chromatography
  • Applications of Column Chromatography
  • Planar Chromatography
  • Reagents Used in Open Bed or Planar Chromatography
  • Applications of Open Bed or Planar Chromatography
  • Paper Chromatography
  • Thin Layer Chromatography
  • Market for Reagents Used in TLC Chromatography
  • Ion Exchange Chromatography
  • Cation Exchange Chromatography
  • Anion Exchange Chromatography
  • Market for Reagents Used in Ion Exchange Chromatography
  • Applications of Ion Exchange Chromatography
  • Size Exclusion Chromatography
  • Applications of Size Exclusion Chromatography
  • Affinity chromatography
  • Market for Reagents Used in Affinity chromatography
  • Applications of Affinity chromatography
  • Partition Chromatography
  • Reverse Phase Partition Chromatography
  • Normal Phase Partition Chromatography
  • Applications of Partition Chromatography
  • Capillary Electrophoresis
  • Market for Reagents Used in Capillary Electrophoresis
  • Others
  • Expanded Bed Adsorption Chromatographic Separation
  • Solid Phase Extraction (SPE)
  • Gas Chromatography-Mass Spectrometry
  • Liquid Chromatography-Mass Spectroscopy (LC-MS)



Chapter 6 End Users of Chromatography
  • Biopharmaceuticals and Pharmaceuticals
  • Drug Discovery
  • Drug Testing
  • Metabolomics
  • Proteomics
  • Exosome Diagnostics and Therapeutics
  • Biosimilars Manufacturing
  • Food and Beverages
  • Environment
  • Clinics and Forensics
  • Petrochemicals/Chemicals
  • Others
  • Analysis of Nanoparticles
  • Glycobiology Research and Development



Chapter 7 Chromatography Reagents Market Breakdown by Region
  • Geographic Market Breakdown of Chromatography Reagents, by Technique
  • Gas Chromatography
  • Liquid and Flash Chromatography
  • Thin Layer Chromatography
  • Affinity chromatography
  • Ion Exchange Chromatography
  • Size Exclusion or Gel Permeation Chromatography
  • Super Critical Fluid Chromatography
  • Capillary Electrophoresis



Chapter 8 Review of Patents and Patent Applications on Chromatography
Chapter 9 Competitive Landscape
  • New Products
  • Mergers and Acquisitions
  • Agreements, Partnerships and Collaborations



Chapter 10 Company Profiles
  • Agilent Technologies
  • Avantor Performance Materials
  • Beckman Coulter Inc.
  • Bio-Rad Laboratories, Inc.
  • Bonn-Agela Technologies Inc.
  • Chiral Technologies Inc.
  • Danaher Corp.
  • Dionex Corp.
  • Extrasynthese
  • GE Healthcare Life Sciences
  • General Separation Technologies Inc. (Gs-Tek)
  • Hamilton Co.
  • Helena Laboratories
  • Hichrom Ltd.
  • Hoefer Inc.
  • Honeywell Burdick & Jackson
  • Jordi Labs
  • Lonza Group Ltd.
  • Millipore Corp.
  • Nacalai Tesque
  • Regis Technologies Inc.
  • Sebia
  • Serva Electrophoresis Gmbh
  • Sigma-Aldrich
  • Sorbent Technologies Inc.
  • Thermo Fisher Scientific Inc.
  • Tosoh Biosciences
  • Waters Corp.
  • W. R. Grace



List of Tables
Summary Table: Global Market for Chromatography Reagents, by Type, Through 2023
Table 1: History of Chromatography, 1906-1987
Table 2: Examples of Solvents Used in Chromatography
Table 3: Buffers Used in Chromatography
Table 4: Adsorbents Used in Gas-Solid and Liquid-Solid Chromatography
Table 5: Advantages and Disadvantages of Derivatives
Table 6: Derivatives Used in Chromatography
Table 7: Resins Used in Chromatography
Table 8: Reagents Used in Gas Chromatography
Table 9: Leading Manufacturers/Suppliers of Gas Chromatography Reagents
Table 10: Global Market Share for the Manufacturers/Suppliers of Gas Chromatography Reagents, 2017
Table 11: Reagents Used in Liquid and Flash Chromatography
Table 12: Leading Manufacturers/Suppliers of Liquid and Flash Chromatography Reagents, 2017
Table 13: Global Market Share for Manufacturers/Suppliers of Liquid and Flash Chromatography Reagents, 2017
Table 14: Reagents Used in Thin Layer Chromatography
Table 15: Leading Manufacturers/Suppliers of Thin Layer Chromatography Reagents, 2017
Table 16: Global Market Share for Manufacturers/Suppliers of Thin Layer Chromatography Reagents, 2017
Table 17: Reagents Used in Affinity Chromatography
Table 18: Leading Manufacturers/Suppliers of Affinity Chromatography Reagents, 2017
Table 19: Global Market Share for Manufacturers/Suppliers of Affinity Chromatography Reagents, 2017
Table 20: Reagents Used in Ion Exchange Chromatography
Table 21: Leading Manufacturers/Suppliers of Ion Exchange Chromatography Reagents, 2017
Table 22: Global Market Share for Manufacturers/Suppliers of Ion Exchange Chromatography Reagents, 2017
Table 23: Reagents Used in Size Exclusion and Gel Permeation Chromatography
Table 24: Leading Manufacturers/Suppliers of Size Exclusion and Gel Permeation Chromatography Reagents, 2017
Table 25: Global Market Share for Manufacturers/Suppliers of Size Exclusion and Gel Permeation Chromatography Reagents, 2017
Table 26: Reagents Used in Capillary Electrophoresis
Table 27: Leading Manufacturers/Suppliers of Capillary Electrophoresis Reagents, 2017
Table 28: Global Market Share for Manufacturers/Suppliers of Capillary Electrophoresis Reagents, 2017
Table 29: Reagents Used in SFC Chromatography
Table 30: Leading Manufacturers/Suppliers of Supercritical Fluid Chromatography Reagents, 2017
Table 31: Global Market Share for Manufacturers/Suppliers of Supercritical Fluid Chromatography Reagents, 2017
Table 32: Advantages and Disadvantages of Chromatographic Techniques
Table 33: Global Market for the Reagents Used in Chromatography, by Technique Type, Through 2023
Table 34: Global Market Share for the Reagents Used in Chromatography, by Technique Type, 2017
Table 35: Advantages and Disadvantages of Gas Chromatography
Table 36: Reagents Used in Gas Chromatography
Table 37: Global Market for the Reagents Used in Gas Chromatography, by Type, Through 2023
Table 38: Global Market Share for the Reagents Used in Gas Chromatography, by Type, 2017
Table 39: Advantages and Disadvantages of HPLC
Table 40: Reagents Used in HPLC
Table 41: Global Market for the Reagents Used in Liquid Chromatography, by Type, Through 2023
Table 42: Global Market Share for the Reagents Used in Liquid Chromatography, by Type, 2017
Table 43: Advantages and Disadvantages of Column Chromatography
Table 44: Reagents Used in Column Chromatography
Table 45: Advantages and Disadvantages of Open Bed or Planar Chromatography
Table 46: Reagents Used in Planar Chromatography
Table 47: Advantages and Disadvantages of Paper Chromatography
Table 48: Global Market for the Reagents Used in Thin Layer Chromatography, by Type, Through 2023
Table 49: Global Market Share for the Reagents Used in Thin Layer Chromatography, by Type, 2017
Table 50: Advantages and Disadvantages of Ion Exchange Chromatography
Table 51: Reagents Used in Ion Exchange Chromatography
Table 52: Global Market for the Reagents Used in Ion Exchange Chromatography, by Type, Through 2023
Table 53: Global Market Share for the Reagents Used in Ion Exchange Chromatography, by Type, 2017
Table 54: Advantages and Disadvantages of Size Exclusion Chromatography
Table 55: Reagents Used in Size Exclusion Chromatography
Table 56: Global Market for the Reagents Used in Gel Permeation or Size Exclusion Chromatography, by Type, Through 2023
Table 57: Global Market Share for the Reagents Used in Gel Permeation or Size Exclusion Chromatography, by Type, 2017
Table 58: Advantages and Disadvantages of Affinity chromatography
Table 59: Reagents Used in Affinity chromatography
Table 60: Global Market for the Reagents Used in Affinity chromatography, by Type, Through 2023
Table 61: Global Market Share for the Reagents Used in Affinity chromatography, by Type, 2017
Table 62: Advantages and Disadvantages of Partition Chromatography
Table 63: Reagents Used in Partition Chromatography
Table 64: Global Market for the Reagents Used in Capillary Electrophoresis, by Type, Through 2023
Table 65: Global Market Share for the Reagents Used in Capillary Electrophoresis, by Type, 2017
Table 66: Global Market for Chromatography Reagents, by Region, Through 2023
Table 67: Global Market Share for Chromatography Reagents, by Region, 2017
Table 68: Global Market for the Reagents Used in Gas Chromatography, by Region, Through 2023
Table 69: Global Market Share for Gas Chromatography Reagents, by Region, 2017
Table 70: Global Market for the Reagents Used in Liquid and Flash Chromatography, by Region, Through 2023
Table 71: Global Market Share for Liquid Chromatography Reagents, by Region, 2017
Table 72: Global Market for the Reagents Used in Thin Layer Chromatography, by Region, Through 2023
Table 73: Global Market Share for Thin Layer Chromatography Reagents, by Region, 2017
Table 74: Global Market for the Reagents Used in Affinity chromatography, by Region, Through 2023
Table 75: Global Market Share for Affinity chromatography Reagents, by Region, 2017
Table 76: Global Market for the Reagents Used in Ion Exchange Chromatography, by Region, Through 2023
Table 77: Global Market Share for Ion Exchange Chromatography Reagents, by Region, 2017
Table 78: Global Market for the Reagents Used in Size Exclusion Chromatography, by Region, Through 2023
Table 79: Global Market Share for SEC Reagents, by Region, 2017
Table 80: Global Market for the Supercritical Fluids Used in Chromatography, by Region, Through 2023
Table 81: Global Market Share for Supercritical Fluids Used in Chromatography, by Region, 2017
Table 82: Global Market for the Reagents Used in Capillary Electrophoresis, by Region, Through 2023
Table 83: Global Market Share for Capillary Electrophoresis Reagents, by Region, 2017
Table 84: Patent and Patent Application Review, 2016-2018
Table 85: New Products Launched, by Key Players of Chromatography Industry, 2017-2018
Table 86: Mergers and Acquisitions, 2017-2018*
Table 87: Agreements, Collaborations and Partnerships Among Chromatography Players, 2016-2018
List of Figures
Summary Figure: Global Market for Chromatography Reagents, by Type, 2017-2023
Figure 1: Classification of Chromatography
Figure 2: Sub-Classification of Chromatographic Segments
Figure 3: Global Market Share for the Manufacturers/Suppliers of Gas Chromatography Reagents, 2017
Figure 4: Global Market Share for Manufacturers/Suppliers of Liquid and Flash Chromatography Reagents, 2017
Figure 5: Global Market Share for Manufacturers/Suppliers of Thin Layer Chromatography Reagents, 2017
Figure 6: Global Market Share for Manufacturers/Suppliers of Affinity Chromatography Reagents, 2017
Figure 7: Global Market Share for Manufacturers/Suppliers of Ion Exchange Chromatography Reagents, 2017
Figure 8: Global Market Share for Manufacturers/Suppliers of Size Exclusion and Gel Permeation Chromatography Reagents, 2017
Figure 9: Global Market Share for Manufacturers/Suppliers of Capillary Electrophoresis Reagents, 2017
Figure 10: Global Market Share for Manufacturers/Suppliers of Supercritical Fluid Chromatography Reagents, 2017
Figure 11: Global Market for the Reagents Used in Chromatography, by Technique Type, 2017-2023
Figure 12: Global Market Share for the Reagents Used in Chromatography, by Technique Type, 2017

Executive Summary

The global market is dominated by North America, followed by Europe and other emerging markets. In the next five years, the growth of the market in the Asia-Pacific region will be centered in China, India, Singapore, Malaysia, Vietnam and Japan. The growth will be driven by the increasing number of conferences on chromatography in Singapore and Malaysia, as well as the expansion of chromatography companies such as Tosoh Biosciences in the countries of China, India, Singapore, Vietnam and Japan. Also, many pharmaceutical companies and labs now outsource their drug discovery and development services to various regions in Asia, especially in China and India. This is fueling the demand of separation
services and a need for chromatography reagents in the emerging markets.

During 2017, the liquid and flash chromatography reagents market held the largest market share, followed by gas chromatography reagents and ion exchange chromatography. North America dominated the chromatography reagents market in the last five years.

The increasing use of chromatography reagents in life science and escalating research has led to concomitant growth for the market leaders who provide columns, resins and other consumables needed for chromatographic analyte separation. The market leaders, such as Agilent and Waters, are proactively introducing products that are adapted to the needs of this market. The technological innovations, enhancements and improvements in design have contributed to the use of chromatographic techniques among a more diverse base of users.

The demand for reagents in the biotechnology market correlates with the growth of the biotechnology instrumentation market, which has continued to grow in the last decade. While the conventional chromatography methods, such as flash chromatography, supercritical fluid chromatography (SFC), etc., are driving the market, the new methods involving chiral separation and simulated moving bed (SM8) chromatography have also had major impacts on the market. Hence, the chromatography reagents market in the next five years will be driven by the increasing use of reagents in therapeutics, basic research and overall commercial applications in the fields of pharmaceuticals, food, environment, petroleum, forensics, security, etc. The major players in this market include Thermo Scientific, Agilent, Danaher (AB Sciex), Tosoh Biosciences, Sigma-Aldrich, WVR, BioRad, EMD, W R Grace and Waters.

Companies Mentioned

  • Agilent Technologies
  • Avantor Performance Materials
  • Beckman Coulter Inc.
  • fBio-Rad Laboratories, Inc.
  • Bonn-Agela Technologies Inc.
  • Chiral Technologies Inc.
  • Danaher (AB Sciex)
  • Dionex Corp.
  • EMD
  • Extrasynthese
  • GE Healthcare Life Sciences
  • General Separation Technologies Inc. (GS-TEK)
  • Hamilton Co.
  • Helena Laboratories
  • Hichrom Ltd.
  • Hoefer Inc.
  • Honeywell Burdick & Jackson
  • Jordi Labs
  • Lonza Group Ltd.
  • Millipore Corp.
  • Nacalai Tesque
  • Regis Technologies Inc.
  • Sebia
  • Serva Electrophoresis Gmbh
  • Sigma-Aldrich
  • Sorbent Technologies Inc.
  • Thermo Fisher Scientific Inc.
  • Tosoh Biosciences
  • W. R. Grace
  • Waters Corp
  • WVR