RNAi therapeutics is now started taking momentum after successful clinical trials for different siRNA-based therapies, primarily for neural disorders and cancers. Their specifications in terms of post-transcriptional gene silencing have already been well established and many small and big players are engaged in designing and patenting novel RNAi sequences. Designing specific sequences for specific disease or disorders does not complete the invention, but it does also require maneuvering specific delivery agents for targeted delivery. Lipid based delivery agents are primarily used for delivering different RNAi molecules, but other chemical agents such as peptides, DAEA-dextran etc. and biological agents such as viral particles have also been tried and tested.
Globally, North America dominates the nucleic acid aptamer market, due to its favorable policies for clinical trials, which is driving the market growth. It is estimated that nucleic acid aptamer market will reach nearly $5.4 billion by 2020, with a compound annual growth rate (CAGR) of 73.5% from 2015 to 2020.
Based on the drug delivery and therapeutics applications the RNAi market is segmented. The drug delivery of RNAi is further divided into nucleic acid drug delivery technology, aptamer drug delivery technology, nanoparticle drug delivery technology, and pulmonary drug delivery technology. Therapeutic application market further segmented into oncology, cardiology, ophthalmology, neurology and metabolic disorders. Nanoparticle based drug delivery is largest sub-segment, however, aptamer drug delivery technology is the fastest growing segment.
More than fifteen hundred clinical trials for nucleic acid delivery are ongoing worldwide. Approximately 55% are in the primary clinical development stage and 4% in phase III trials which shows that nucleic acid delivery market is growing rapidly.
Nucleic acid used for therapeutics
Geographically IP filing activity
In Asia, less filing has been observed in this domain in 2017. Japan (XX) is the most active jurisdiction, followed by China (XX), Korea (XX) and India (XX).
Key Coverage
Key topics covered includes
Key questions answered in the report
Globally, North America dominates the nucleic acid aptamer market, due to its favorable policies for clinical trials, which is driving the market growth. It is estimated that nucleic acid aptamer market will reach nearly $5.4 billion by 2020, with a compound annual growth rate (CAGR) of 73.5% from 2015 to 2020.
Based on the drug delivery and therapeutics applications the RNAi market is segmented. The drug delivery of RNAi is further divided into nucleic acid drug delivery technology, aptamer drug delivery technology, nanoparticle drug delivery technology, and pulmonary drug delivery technology. Therapeutic application market further segmented into oncology, cardiology, ophthalmology, neurology and metabolic disorders. Nanoparticle based drug delivery is largest sub-segment, however, aptamer drug delivery technology is the fastest growing segment.
More than fifteen hundred clinical trials for nucleic acid delivery are ongoing worldwide. Approximately 55% are in the primary clinical development stage and 4% in phase III trials which shows that nucleic acid delivery market is growing rapidly.
Nucleic acid used for therapeutics
Geographically IP filing activity
In Asia, less filing has been observed in this domain in 2017. Japan (XX) is the most active jurisdiction, followed by China (XX), Korea (XX) and India (XX).
Key Coverage
- Overview of Nucleic acid delivery, including unique challenges, categories of RNA interference (RNAi) used for therapy, specific carriers and technique of delivering nucleic acid, role of delivery systems in therapy and disease covered.
- Different nucleic acids used for therapy such as SiRNA, miRNA, mRNA, shRNA, gRNA. Studies on current academic research and industry trend, geographical distribution of therapeutics, key diseases targeted for treatment, clinical trials for different diseases, different delivery agents and techniques to deliver nucleic acid utilized.
Key topics covered includes
- Nucleic acid delivery market segmentation by geography, application, end user & product
- Industry movement partnerships, agreements, collaborations, expansions, acquisitions, and product & service launches in the market
- Strategic SWOT & PEST analysis, nucleic acid delivery market characterization i.e. development and determinants
- Analysis of the current and future market drift in the global Nucleic acid delivery market. Perspicacious review of the key industry opportunity, restraints and, challenges
- Market assessment of nucleic acid delivery in therapeutics
Key questions answered in the report
- What are different types of nucleic acid used as therapeutic agents?
- What are different nucleic acid delivery agents and delivery techniques used?
- What are the key challenges associated with the current delivery systems?
- Will the pipeline carriers under development and clinical trials overcome these challenges and problems associated with current delivery systems?
- What is the technology trend prevalent in usage of RNAi as therapeutic agent?
- Who are the key companies & universities actively working on usage of RNAi as therapeutic agent?
- What are the key disease targeted i.e. animal and plant diseases?
- What are the different plant diseases covered and future prospect of RNAi as a biosafe ecofriendly tool for plant pathologists?
- What are the technological innovations pursued by these companies & universities?
- What are the opportunities and restraints for RNAi delivery technologies in therapeutics?
- What are the technology forecasts & core technologies, ongoing prosecutions, statistical analytics, citations & classifications etc. for RNAi as therapeutic agent?
- What are the market determinants and market trends with respect to different geographic regions?
- What are the major industrial movements in terms of partnerships, agreements, collaborations, expansions, acquisitions, and product & service launches in the market?
Table of Contents
1. Technology Overview
2. Technology Insights
3. Geographical distribution
4. Partnership / Collaboration / Licensing
5. Nucleic acid delivery – Market overview
Methodology
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