Acromegaly - Market Insights, Epidemiology and Market Forecast-2027

  • ID: 4618389
  • Drug Pipelines
  • 162 Pages
  • DelveInsight
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until Dec 31st 2018
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FEATURED COMPANIES

  • Antisense Therapeutics
  • Aspireo Pharmaceuticals
  • Ionis Pharmaceuticals
  • Ipsen Pharmaceuticals
  • Novartis
  • Pharmacia & Upjohn
  • MORE

‘Acromegaly - Market Insights, Epidemiology and Market Forecast-2027’ report delivers an in-depth understanding of the disease, historical & forecasted epidemiology as well as the market trends of Acromegaly in the United States, EU5 (Germany, Spain, Italy, France and United Kingdom), and Japan.

The Report provides the current treatment practices, emerging drugs, market share of the individual therapies, current and forecasted market size of Acromegaly from 2016 to 2027 segmented by seven major markets. The Report also covers the current treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assess underlying potential of the market.

Geography Covered:

  • The United States
  • EU5 (Germany, France, Italy, Spain and the United Kingdom)
  • Japan

Study Period: 2016-2027

Acromegaly- Disease Understanding and Treatment Algorithm

The Acromegaly market report gives the thorough understanding of the Acromegaly by including details such as disease definition, classification, symptoms, etiology, pathophysiology, diagnostic trends. It also provides treatment algorithms and treatment guidelines for Acromegaly in the US, Europe, and Japan.

Acromegaly Epidemiology

The Acromegaly epidemiology division provides the insights about historical and current patient pool and forecasted trend for every 7 major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of The report also provides the diagnosed patient pool and their trends along with assumptions undertaken.

The disease epidemiology covered in the report provides historical as well as forecasted epidemiology (total prevalent cases, origin-based cases, diagnosed cases, diagnosed cases based on type of adenomas and treatable cases) scenario of Acromegaly in the 7MM covering United States, EU5 countries (Germany, Spain, Italy, France and United Kingdom) and Japan from 2016-2027.
According this research, the total number of prevalent population of Acromegaly was found to be 60,610, in the year 2016.

Acromegaly Drug Chapters

This segment of the Acromegaly report encloses the detailed analysis of marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. It also helps to understand the clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases.

Present medical therapies available to treat Acromegaly consist of Somatostatin Analogues (SSAs) and Dopamine Agonist (DA) medication, both of which act to suppress GH secretion from pituitary adenomas or remnant tissue and thus lead to reduced IGF-1 levels and reduced symptoms. The GH receptor antagonist Pegvisomant is helpful in patients who are resistant or partially respondent to Somatostatin Analogs. Seven therapies, five Somatostatin Analogs, and two Growth Hormone Receptor Antagonists are expected to enter the 7MM Acromegaly market by 2027. Detailed chapter of Somatostatin Analogs (Octreotide capsules, Lanreotide PRF, Veldoreotide, CAM2029, GT-02037), and Growth hormone receptor antagonists (IONIS-GHR-LRx, ATL1103)) have been covered in the report.

Acromegaly Market Outlook

The Acromegaly market outlook of the report helps to build the detailed comprehension of the historic, current and forecasted trend of the market by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better technology.

This segment gives a through detail of market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on annual cost of therapy, inclusion and exclusion criteria’s, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

Acromegaly Drugs Uptake

This section focusses on the rate of uptake of the potential drugs recently launched in the market or will get launched in the market during the study period from 2016-2027. The analysis covers market uptake by drugs; patient uptake by therapies and sales of each drug.

This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allows the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

Acromegaly Report Insights

  • Patient Population
  • Therapeutic Approaches
  • Pipeline Analysis
  • Market Size and Trends
  • Market Opportunities
  • Impact of upcoming Therapies

Acromegaly Report Key Strengths

  • 10 Year Forecast
  • 7MM Coverage
  • Epidemiology Segmentation
  • Drugs Uptake
  • Highly Analyzed Market
  • Key Cross Competition

Acromegaly Report Assessment

  • Current Treatment Practices
  • Unmet Needs
  • Detailed Pipeline Product Profiles
  • Market Attractiveness
  • Market Drivers and Barriers

Key Benefits:

  • This report will help to develop Business Strategies by understanding the trends shaping and driving Acromegaly market
  • Organize sales and marketing efforts by identifying the best opportunities for Acromegaly market
  • To understand the future market competition in the Acromegaly market.
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Note: Product cover images may vary from those shown
2 of 4

FEATURED COMPANIES

  • Antisense Therapeutics
  • Aspireo Pharmaceuticals
  • Ionis Pharmaceuticals
  • Ipsen Pharmaceuticals
  • Novartis
  • Pharmacia & Upjohn
  • MORE
1. Key Insights

2. Acromegaly Market Overview at a Glance
2.1. Market (%) Distribution of Acromegaly in 2017
2.2. Market (%) Distribution of Acromegaly in 2027

3. Disease Overview: Acromegaly (ACM)
3.1. Introduction
3.2. Signs and Symptoms
3.3. Classification of Pituitary Adenomas
3.4. Clinical Manifestations of Acromegaly
3.5. Etiology
3.6. Pathophysiology
3.7. Genetic bases of acromegaly
3.8. Pathogenesis
3.9. Diagnosis
3.9.1. Diagnosis guidelines
3.9.2. Endocrine Society Clinical Practice Guideline-United Kingdom
3.9.3. American Association of Clinical Endocrinologists (AACE) - U.S.A.

4. Epidemiology and Patient Population

5. Key Findings

6. 7MM Epidemiology
6.1. Total Prevalent Cases of Acromegaly in 7MM
6.2. Origin Based Cases of Acromegaly in 7MM

7. United States Epidemiology
7.1. Total Prevalent Cases of Acromegaly in the United States
7.2. Origin-Based Cases of Acromegaly in the United States
7.3. Diagnosed Cases of Acromegaly in the United States
7.4. Diagnosed Cases of Acromegaly Based on Types of Adenomas in the United States
7.5. Treatable Cases of Acromegaly in the United States

8. EU5 Epidemiology
8.1. United Kingdom
8.1.1. Total Prevalent Cases of Acromegaly in the United Kingdom
8.1.2. Origin-Based Cases of Acromegaly in the United Kingdom
8.1.3. Diagnosed Cases of Acromegaly in the United Kingdom
8.1.4. Diagnosed Cases of Acromegaly Based on Types of Adenomas in the United Kingdom
8.1.5. Treatable Cases of Acromegaly in the United Kingdom
8.2. Germany
8.2.1. Total Prevalent Cases of Acromegaly in Germany
8.2.2. Origin-Based Cases of Acromegaly in Germany
8.2.3. Diagnosed Cases of Acromegaly in Germany
8.2.4. Diagnosed Cases of Acromegaly Based on Types of Adenomas in Germany
8.2.5. Treatable Cases of Acromegaly in Germany
8.3. France
8.3.1. Total Prevalent Cases of Acromegaly in France
8.3.2. Origin Based Cases of Acromegaly in France
8.3.3. Diagnosed Cases of Acromegaly in France
8.3.4. Diagnosed Cases of Acromegaly Based on Types of Adenomas in France
8.3.5. Treatable Cases of Acromegaly in France
8.4. Italy
8.4.1. Total Prevalent Cases of Acromegaly in Italy
8.4.2. Origin-Based Cases of Acromegaly in Italy
8.4.3. Diagnosed Cases of Acromegaly in Italy
8.4.4. Diagnosed Cases of Acromegaly Based on Types of Adenomas in Italy
8.4.5. Treatable Cases of Acromegaly in Italy
8.5. Spain
8.5.1. Total Prevalent Cases of Acromegaly in Spain
8.5.2. Origin-Based Cases of Acromegaly in Spain
8.5.3. Diagnosed Cases of Acromegaly in Spain
8.5.4. Diagnosed Cases of Acromegaly Based on Types of Adenomas in Spain
8.5.5. Treatable Cases of Acromegaly in Spain

9. Japan Epidemiology
9.1. Total Prevalent Cases of Acromegaly in Japan
9.2. Origin-Based Cases of Acromegaly in Japan
9.3. Diagnosed Cases of Acromegaly in Japan
9.4. Diagnosed Cases of Acromegaly Based on Types of Adenomas in Japan
9.5. Treatable Cases of Acromegaly in Japan

10. Treatment
10.1. Biomarkers of Acromegaly
10.2. Treatment Guidelines
10.2.1. American Association of Clinical Endocrinologists (AACE) - U.S.A.
10.2.2. Endocrine Society Clinical Practice Guideline-United Kingdom

11. Unmet Needs

12. Marketed Drug
12.1. Somatuline Depot (lanreotide acetate): Ipsen Biopharmaceuticals
12.1.1. Drug Description
12.1.2. Mechanism of Action
12.1.3. Regulatory Milestones
12.1.4. Advantages & Disadvantages
12.1.5. Safety and Efficacy
12.1.6. Product Profile
12.2. Somavert (pegvisomant): Pharmacia & Upjohn
12.2.1. Drug Description
12.2.2. Mechanism of Action
12.2.3. Regulatory Milestones
12.2.4. Advantages & Disadvantages
12.2.5. Safety and Efficacy
12.2.6. Product Profile
12.3. Sandostatin LAR Depot: Novartis Pharmaceuticals
12.3.1. Drug Description
12.3.2. Mechanism of Action
12.3.3. Regulatory Milestones
12.3.4. Advantages & Disadvantages
12.3.5. Safety and Efficacy
12.3.6. Product Profile
12.4. Signifor LAR (pasireotide): Novartis Pharmaceuticals
12.4.1. Drug Description
12.4.2. Mechanism of Action
12.4.3. Regulatory Milestones
12.4.4. Advantages & Disadvantages
12.4.5. Safety and Efficacy
12.4.6. Product Profile

13. Key Cross Competitors

14. Emerging Drugs
14.1. IONIS-GHR-LRx: Ionis Pharmaceuticals
14.1.1. Product Description
14.1.2. Other Developmental Activities
14.1.3. Clinical Development
14.1.4. Clinical Trials Information
14.1.5. Safety and Efficacy
14.1.6. Product Profile
14.2. Octreotide capsules: Chiasma Pharma
14.2.1. Product Description
14.2.2. Other Developmental Activities
14.2.3. Clinical Development
14.2.4. Clinical Trials Information
14.2.5. Safety and Efficacy
14.2.6. Product Profile
14.3. ATL1103: Antisense Therapeutics
14.3.1. Product Description
14.3.2. Other Developmental Activities
14.3.3. Clinical Development
14.3.4. Clinical Trials Information
14.3.5. Safety and Efficacy
14.3.6. Product Profile
14.4. CAM2029: Novartis
14.4.1. Product Description
14.4.2. Other Developmental Activities
14.4.3. Clinical Development
14.4.4. Clinical Trials Information
14.4.5. Safety and Efficacy
14.4.6. Advantages and Disadvantages
14.4.7. Product Profile
14.5. GT-02037: Pharmaspur
14.5.1. Product Description
14.5.2. Clinical Development
14.5.3. Clinical Trials Information
14.5.4. Product Profile
14.6. Veldoreotide: Evotec/ Aspireo Pharmaceuticals
14.6.1. Product Description
14.6.2. Other Developmental Activities
14.6.3. Clinical Development
14.6.4. Clinical Trials Information
14.6.5. Safety and Efficacy
14.6.6. Advantages and Disadvantages
14.6.7. Product Profile

15. Acromegaly: 7Major Market Analysis
15.1. Key Findings
15.2. Market Size of Acromegaly in 7MM

16. The United States: Market Outlook
16.1. The United States Market Size
16.2. Total Market size of Acromegaly
16.3. Market Size by Therapies

17. EU5: Market Outlook
17.1. The United Kingdom Market Size
17.1.1. Total Market size of Acromegaly
17.1.2. Market Size by Therapies
17.2. Germany Market Size
17.2.1. Total Market size of Acromegaly
17.2.2. Market Size by Therapies
17.3. France Market Size
17.3.1. Total Market size of Acromegaly
17.3.2. Market Size by Therapies
17.4. Italy Market Size
17.4.1. Total Market size of Acromegaly
17.4.2. Market Size by Therapies
17.5. Spain Market Size
17.5.1. Total Market size of Acromegaly
17.5.2. Market Size by Therapies

18. Japan: Market Outlook
18.1. Japan Market Size
18.1.1. Total Market size of WM
18.1.2. Market Size by Therapies

19. Market Drivers

20. Market Barriers

21. Appendix
21.1. Report Methodology

22. The Publisher Capabilities

23. Disclaimer

24. About the publisher
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  • Ipsen Pharmaceuticals
  • Pharmacia & Upjohn
  • Novartis
  • Ionis Pharmaceuticals
  • Antisense Therapeutics
  • Pharmaspur
  • Aspireo Pharmaceuticals
Note: Product cover images may vary from those shown
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