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Microbiome Collaboration and Licensing Deals 2016-2026

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    Report

  • 200 Pages
  • May 2026
  • Region: Global
  • CurrentPartnering
  • ID: 4636692

The definitive benchmark for microbiome dealmaking

Microbiome partnering is driven by emerging science and novel therapeutic approaches, with deal structures reflecting platform-based technologies, live biotherapeutics, and data-driven discovery.

This report provides a comprehensive and structured analysis of 250+ microbiome collaboration and licensing deals, delivering a clear and evidence-based view of how partnerships are designed, negotiated, and executed across the market.

Establish a clear view of market standards

The report enables a precise understanding of how microbiome deals are structured in practice, allowing you to:

  • Benchmark comparable transactions with confidence
  • Detailed analysis of upfronts, milestones, and royalty structures across relevant deals
  • Define realistic market parameters
  • Clear insight into how deal terms vary by platform type, application, and partner profile
  • Support valuation and structuring decisions with evidence
  • Ground internal discussions in real transaction data rather than assumptions
  • Understand how leading companies approach dealmaking
  • Visibility into partner behaviour and recurring deal structures across a highly innovative and still-evolving therapeutic landscape
  • Full visibility into deal structure and execution
Beyond headline deal data, the report provides access to underlying contract documents, enabling a detailed understanding of how agreements are constructed in practice.

This includes:

  • Rights granted and retained
  • Development and commercialization responsibilities
  • Financial structures and payment triggers
  • Key contractual provisions and protections
This level of transparency is critical to understanding how value, risk, and control are allocated within microbiome partnerships, particularly in areas involving novel mechanisms of action and emerging clinical validation.

Designed for real-world BD and strategy use

The report is widely used to:

  • Structure and benchmark emerging technology transactions
  • Prepare for negotiations with well-defined market context
  • Evaluate platform partnerships and collaboration opportunities
  • Support internal strategy with robust, defensible data

What’s included?

  • 250+ microbiome collaboration and licensing deals
  • Financial terms, including upfronts, milestones, and royalties where disclosed
  • Fully searchable deal directory (by company, platform, and application)
  • Direct access to SEC-filed agreements and source documents
  • Analysis of deal trends, key transactions, and active dealmakers
  • A trusted, evidence-based reference for microbiome dealmaking
Combining comprehensive deal coverage with contract-level insight, this report provides a trusted, evidence-based reference for how microbiome partnerships are structured, negotiated, and valued.

Table of Contents

Executive SummaryChapter 1 - Introduction
Chapter 2 - Trends in microbiome dealmaking
2.1. Introduction
2.2. Microbiome deals over the years
2.3. Most active microbiome dealmakers
2.4. Microbiome deals by deal type
2.5. Microbiome deals by therapy area
2.6. Microbiome deals by industry sector
2.7. Deal terms for microbiome deals
2.7.1 Microbiome deals headline values
2.7.2 Microbiome deal upfront payments
2.7.3 Microbiome deal milestone payments
2.7.4 Microbiome royalty rates
Chapter 3 - Leading microbiome deals
3.1. Introduction
3.2. Top microbiome deals by value
Chapter 4 - Most active microbiome dealmakers
4.1. Introduction
4.2. Most active microbiome dealmakers
4.3. Most active microbiome deals company profiles
Chapter 5 - Microbiome contracts dealmaking directory
5.1. Introduction
5.2. Microbiome contracts dealmaking directory
Chapter 6 - Microbiome dealmaking by technology type
Deal directory
  • Deal directory - Microbiome deals by company A-Z
  • Deal directory - Microbiome deals by deal type
  • Deal directory - Microbiome deals by therapy area
  • Deal type definitions
List of Figures
Figure 1: Microbiome deals since 2016
Figure 2: Active microbiome dealmaking activity since 2016
Figure 3: Microbiome deals by deal type since 2016
Figure 4: Microbiome deals by therapy area since 2016
Figure 5: Microbiome deals by industry sector since 2016
Figure 6: Microbiome deals with a headline value
Figure 7: Microbiome deals with an upfront value
Figure 8: Microbiome deals with a milestone value
Figure 9: Microbiome deals with a royalty rate value
Figure 10: Top microbiome deals by value since 2016
Figure 11: Most active microbiome dealmakers since 2016
Figure 12: Microbiome deals by technology type since 2016

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • 4D Pharma
  • 9 Meters Biopharma
  • Aarhus University
  • Abbvie
  • ADL Bionatur Solutions
  • ADM
  • AiCuris
  • Allergan
  • ALS Association
  • Amag Pharmaceuticals
  • American Skin Association
  • American Type Culture Collection (ATCC)
  • AnimalBiome
  • AntibioTx
  • Arc Bio
  • Archer Daniels Midland Company
  • Arena Pharmaceuticals
  • Argonne National Laboratory
  • Arranta Bio
  • Artizan Biosciences
  • Assembly Biosciences
  • AstraZeneca
  • Aurealis Therapeutics
  • Azitra
  • Bacthera
  • BASF
  • Bayer
  • Bayer CropScience
  • Baylor College of Medicine
  • Baylor Miraca Genetics Laboratories
  • BCD Bioscience
  • Beam Therapeutics
  • Bertin Pharma
  • Bill and Melinda Gates Foundation
  • Bio-Me
  • Bio-Rad Laboratories
  • BIOASTER
  • Biocodex Microbiota Foundation
  • Biocogent
  • Biocore
  • Biofortis
  • Biohaven Pharmaceuticals
  • BIOHM Health Inc
  • BiomeBank
  • Biomedical Advanced Research and Development Authority
  • Biomica
  • Biomillenia
  • Biomodels
  • BiomX
  • BionX Medical Technologies
  • Bio Palette
  • Biosortia Pharmaceuticals
  • bitBiome
  • Bloom Science
  • Boehringer Ingelheim
  • Boston University School of Medicine
  • Brigham and Women's Hospital
  • Bristol-Myers Squibb
  • Broad Institute
  • Brown University
  • Cancer Research UK
  • CARB-X
  • Carbiotix
  • Cargill
  • Cedars-Sinai Medical Center
  • Centers for Disease Control and Prevention
  • Children's Hospital Boston
  • Circuit Clinical
  • Clalit Health Services
  • CN Bio
  • Columbia University
  • Columbia University Medical Center
  • Commense
  • Compass Minerals Plant Nutrition
  • ConsortiaTX
  • COPD Foundation
  • CoreBiome
  • Cornell University
  • Corteva Agriscience
  • CosmosID
  • Crohn's and Colitis Foundation of America
  • CSIR - Institute of Microbial Technology
  • Dana-Farber Cancer Institute
  • DayTwo
  • DDL Diagnostic Laboratory
  • Debiopharm
  • Defense Advanced Research Projects Agency
  • Dermala
  • Diversigen
  • DuPont
  • DuPont Pharmaceuticals
  • DuPont Pioneer
  • Eagle Genomics
  • EcoMetrix
  • Elanco
  • Eligo Bioscience
  • Emory University
  • Emulate
  • Enterome Bioscience
  • Euformatics
  • European Commission
  • Evah
  • Evelo Biosciences
  • Evogene
  • Evolve BioSystems
  • Evvy
  • Exacta Bioscience
  • Federation Bio
  • Felix Biotechnology
  • Ferring Pharmaceuticals
  • Finch Therapeutics
  • Florida International University
  • Food Marble Digestive Health
  • Forsyth Institute
  • Fred Hutchinson Cancer Research Center
  • French National Institute for Agricultural Research
  • Fundacion Progreso y Salud
  • Galmed Pharmaceuticals
  • Genentech
  • General Automation Lab Technologies
  • Genetic Analysis
  • Genome and Company
  • GI Innovation
  • Gilead Sciences
  • Ginkgo BioWorks
  • Glycosyn
  • Gnubiotics Sciences
  • GSK
  • Gusto Global
  • Hackensack Meridian Health
  • Hadassah Medical Center
  • Harvard Medical School
  • Harvard T.H. Chan School of Public Health
  • Harvard University
  • Health Canada
  • Helomics
  • Holobiome
  • Horizon Europe
  • Hudson Institute of Medical Research
  • IBM
  • iGenomix
  • Illumina
  • Innovate Biopharmaceuticals
  • Inserm
  • Inspirotec
  • Institut Gustave Roussy
  • Institut National Recherche Agronomique
  • International Centre for Diarrhoeal Disease Research
  • International Flavors and Fragrances
  • Intract Pharma
  • Intralytix
  • ISOThrive
  • Jackson Laboratory
  • Janssen Human Microbiome Institute
  • Janssen Research & Development
  • Janssen Therapeutics
  • Jennewein Biotechnologie
  • Johns Hopkins University
  • Johnson & Johnson Consumer Companies
  • Johnson & Johnson Innovation
  • JSR
  • Juntendo University
  • Kaleido Biosciences
  • Kallyope
  • Kantonsspital St. Gallen
  • Kanvas Biosciences
  • Karolinska Institute
  • Keio Gijuku University
  • King's College Hospital
  • Kings College London
  • L'Oreal
  • Latham BioPharm Group
  • Lavie Bio
  • Lawrence Livermore National Laboratory
  • Leiden University
  • Leidos
  • LNC
  • Locus Biosciences
  • Loop Genomics
  • Loreal
  • Lupus Research Alliance
  • Lurie Children's Hospital of Chicago
  • Lysando
  • MaaT Pharma
  • Mainz Biomed
  • Marrone Bio Innovations
  • Mars Petcare
  • Maruho
  • Massachusetts General Hospital
  • Massachusetts Institute of Technology
  • Massachusetts Life Sciences Center
  • Mawi DNA Technologies
  • Mayo Clinic
  • McGill University
  • MD Anderson Cancer Center
  • Medical College of Wisconsin
  • Medical University of Graz
  • Melanoma Research Alliance
  • Memorial Sloan Kettering Cancer Center
  • Merck KGaA
  • Metabiomics
  • MetaboGen
  • Micreos
  • Microba Life Sciences
  • Microbiome Insights
  • MicroBiome Therapeutics
  • Microbiome Therapeutics Innovation Group
  • Microbiotica
  • MicroGenDX
  • Micronoma
  • Microsoft
  • Microviable Therapeutics
  • MilliporeSigma
  • Monsanto
  • Moss Genomics
  • MRM Health
  • MSD
  • MyBiotics Pharma
  • National Cancer Center of Japan
  • National Eczema Association
  • National Institute of Arthritis and Musculoskeletal Diseases
  • National Institutes of Health
  • National Organization for Rare Disorders
  • National Psoriasis Foundation
  • Nestle Health Science
  • Nexilico
  • Northeastern University
  • Northwestern University
  • North Zealand University Hospital
  • Norwegian University of Science
  • Novome Biotechnologies
  • NuBiyota
  • Nutricion
  • Nutrilinea
  • NYU Langone Medical Center
  • Oklahoma Medical Research Foundation
  • Oncology Venture
  • One Codex
  • OpenBiome
  • Opentrons Labworks
  • OptiBiotix
  • Osel
  • Oslo University Hospital
  • Owlstone Medical
  • Pancreatic Cancer Collective
  • Pathogen and Microbiome Institute
  • Penn State Microbiome Center
  • Pennsylvania State University
  • Persephone Biosciences
  • Pfizer
  • PharmaBiome
  • Pharmabiota
  • Pharmatest Services
  • Plan France Relance
  • Pragma Bio
  • Precision Biomonitoring
  • Prescient Medical
  • Proteic Bioscience
  • Puma Biotechnology
  • Purdue Research Foundation
  • Purdue University
  • PureTech Health
  • QIAGEN
  • Quadram Institute
  • Quark Venture
  • Rebiotix
  • ReproCell
  • Research Council of Norway
  • Resilient Biotics
  • RIKEN Research Institute
  • Ritter Pharmaceuticals
  • Roquette
  • Roswell Park Cancer Institute
  • Rutgers University
  • SACCO
  • Salix Pharmaceuticals
  • Samsung Biologics
  • SATT Lutech
  • Second Genome
  • Sequential Skin
  • Seres Therapeutics
  • Servatus Biopharmaceuticals
  • Seven Bridges Genomics
  • Shanghai Lishan Biopharmaceuticals
  • Sheba Medical Center
  • Siolta Therapeutics
  • Sirenas
  • SKAN Research Trust
  • Skive Hospital
  • SkyePharma
  • Solarea Bio
  • Sonic Healthcare
  • Spanish National Cancer Research Centre
  • Stanford Cancer Institute
  • Stanford University School of Medicine
  • Statens Serum Institute
  • Sun Genomics
  • Swiss Integrative Center for Human Health
  • Synlogic
  • Synthetic Biologics
  • Taconic Biosciences
  • Takeda Pharmaceutical
  • Tata Chemicals
  • Tel Aviv University
  • Texas Children’s Hospital
  • The BioCollective
  • The Healthy Aging Company
  • The Parker Institute For Cancer Immunotherapy
  • Thermo Fisher Scientific
  • Tokyo Medical and Dental University
  • Transnetyx
  • Tsinghua University
  • uBiome
  • Unilever
  • UNION Therapeutics
  • Universite catholique de Louvain
  • University Medical Center Utrecht
  • University of Adelaide
  • University of Alberta
  • University of British Columbia
  • University of Buffalo
  • University of California
  • San Diego
  • University of California Irvine
  • University of California Los Angeles
  • University of California San Francisco
  • University of Cambridge
  • University of Chicago
  • University of Cincinnati
  • University of Heidelberg
  • University of Houston
  • University of Illinois
  • University of Lausanne
  • University of Manchester
  • University of Maryland School of Medicine
  • University of Massachusetts Medical School
  • University of Miami
  • University of Michigan
  • University of Minnesota
  • University of Nebraska
  • University of New South Wales
  • University of Oslo
  • University of Pennsylvania
  • University of Pittsburgh
  • University of Queensland
  • University of Rhode Island
  • University of Sheffield
  • University of South Alabama (USA) Mitchell Cancer Institute
  • University of South Carolina
  • University of Texas
  • University of Verona
  • University of Virginia
  • University of Washington
  • University Paris Diderot
  • Valbiotis
  • Vanderbilt University
  • Vedanta Biosciences
  • Verb Biotics
  • Vertex Pharmaceuticals
  • ViennaLab Diagnostics
  • Viome
  • Virginia Catalyst
  • Virginia Commonwealth University
  • Virginia Tech
  • Washington University in St Louis
  • Weizmann Institute
  • Xbiome
  • Xycrobe Therapeutics
  • Yale School of Medicine
  • Yale University
  • Yeda Research and Development Company
  • Yili Industrial Group
  • Zymo Research

Methodology

  • The publisher reports provide insight into the trends and terms of partnering deals in the global life sciences sector.
  • The publisher reports are updated every six months to ensure the user has access to the latest announcements and trends in the topic focus of the report.
  • The publisher analysts review the deal data to provide an overview and analysis of deal trends, including example deals and terms.
  • The publisher reports source deal data from our proprietary deals and alliances database. The database is updated daily by our analysts with new deals as they are announced globally by the company’s party to the deal.
  • The data in the deals and alliances database is obtained from secondary sources such as publicly available industry sources including press releases, company presentations, investor presentations, company SEC filings, other company filings, company websites, conference presentations. Sources are identified to allow for user verification.

The publisher provides comprehensive coverage of the following partnering or deal types:

  • Asset purchase
  • Assignment
  • Co-development
  • Co-market
  • Co-promotion
  • Collaborative R&D
  • Contract service
  • CRADA
  • Cross-licensing
  • Development
  • Distribution
  • Equity purchase
  • Evaluation
  • Grant
  • Joint venture
  • Licensing
  • Loan
  • Manufacturing
  • Marketing
  • Option
  • Promotion
  • Research
  • Royalty financing
  • Settlement
  • Spin out
  • Sub license
  • Supply
  • Termination
  • Warrant

Every deal record is fully categorized and includes the following data, where available:

  • Industry sector
  • Therapy areas
  • Technology type
  • Deal components
  • Financial terms
  • Stage of development
  • Exclusivity
  • Asset type
  • Geographic focus
  • Excluded geography
  • Company press release
  • SEC filing data including contract document

All financial amounts are converted to US$ using the exchange rate available on the date of deal announcement, enabling direct comparison of deal terms across international territories.

 

 

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