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Down Syndrome - Market Insights, Epidemiology and Market Forecast-2027

  • ID: 4661522
  • Drug Pipelines
  • October 2018
  • Region: Global
  • 120 pages
  • DelveInsight

FEATURED COMPANIES

  • AC Immune
  • Balance Therapeutics
  • Eisai
  • MORE
‘Down Syndrome - Market Insights, Epidemiology and Market Forecast-2027’ report delivers an in-depth understanding of the disease, historical & forecasted epidemiology as well as the market trends of Down Syndrome in the United States, EU5 (Germany, Spain, Italy, France and United Kingdom), and Japan.

The Report provides the current treatment practices, emerging drugs, market share of the individual therapies, current and forecasted market size of Down syndrome from 2016 to 2027 segmented by seven major markets. The Report also covers current treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assess underlying potential of the market.

Geography Covered
  • The United States
  • EU5 (Germany, France, Italy, Spain and the United Kingdom)
  • Japan
Study Period: 2016-2027

Down syndrome - Disease Understanding and Treatment Algorithm

The Down Syndrome market report gives the thorough understanding of the Down syndrome by including details such as disease definition, classification, symptoms, etiology, pathophysiology, diagnostic trends. It also provides treatment algorithms and treatment guidelines for Down syndrome in the US, Europe, and Japan.

Down syndrome Epidemiology

The Down syndrome epidemiology division provide the insights about historical and current patient pool and forecasted trend for every 7 major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of The report also provides the diagnosed and treatable patient pool and their trends along with assumptions undertaken.

The disease epidemiology covered in the report is segmented by gender- specific [Male and Female] and type specific [Trisomy 21, Mosaicism and Translocation] and diagnosed prevalent population of Down syndrome by clinical manifestation (Congenital heart disease, Ophalmologic complication, Neurological disorder, Hematologic - transient myeloproliferative disorder, Gastro intestinal, Otolaryngology, Endocrinlogy and Others).

According to this research, the prevalent cases of Down syndrome was 541,538 in 2016 in 7 MM and, is expected to increase during the study period i.e., 2016-2027. Among 7MM, United States account for highest prevalent cases of Down syndrome with 258,502 prevalent cases in 2016. In 7MM, males had highest prevalent cases of DS as compared to females in 2016. This trend is expected to increase during the study period

Down syndrome Drug Chapters

This segment of the Down syndrome report encloses the detailed analysis of marketed drugs and late stage (Phase-III) pipeline drugs. It also helps to understand the clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases. This report includes detailed chapters of promising upcoming therapies.

Down syndrome Market Outlook

The Down syndrome market outlook of the report helps to build the detailed comprehension of the historic, current and forecasted trend of the market by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better technology.

This segment gives a through detail of market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on annual cost of therapy, inclusion and exclusion criteria’s, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

Down syndrome market is expected to grow during the forecasted period of 2018-2027 owing to the launch of few drugs (presently in Phase III and Phase II). Down syndrome therapeutics market has seen a 7MM sales of USD 1621.40 Million in 2016.

Down syndrome Drugs Uptake

This section focusses on the rate of uptake of the potential drugs recently launched in the market or will get launched in the market during the study period from 2016-2027. The analysis covers market uptake by drugs; patient uptake by therapies and sales of each drug.

This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allows the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

Down syndrome Report Insights
  • Patient Population
  • Therapeutic Approaches
  • Pipeline Analysis
  • Market Size and Trends
  • Market Opportunities
  • Impact of upcoming Therapies
Down syndrome Report Key Strengths
  • 10 Year Forecast
  • 7MM Coverage
  • Epidemiology Segmentation
  • Drugs Uptake
  • Highly Analyzed Market
  • Key Cross Competition
Down syndrome Report Assessment
  • Current Treatment Practices
  • Unmet Needs
  • Detailed Pipeline Product Profiles
  • Market Attractiveness
  • Market Drivers and Barriers
Key Benefits
  • This report will help to develop Business Strategies by understanding the trends shaping and driving the Down syndrome market
  • Organize sales and marketing efforts by identifying the best opportunities for Down syndrome market
  • To understand the future market competition in the Down syndrome market.
Note: Product cover images may vary from those shown

FEATURED COMPANIES

  • AC Immune
  • Balance Therapeutics
  • Eisai
  • MORE
1. Key Insights

2. Down syndrome: Market Overview at a Glance
2.1. Total Market Share (%) Distribution of Down syndrome in 2016
2.2. Total Market Share (%) Distribution of Down syndrome in 2027

3. Down syndrome: Disease Background and Overview
3.1. Introduction
3.2. Types of Down syndrome
3.3. Etiopathogenesis
3.4. Phenotypic Variability of Down syndrome
3.5. Metabolic Imbalance in Down syndrome
3.6. Clinical Conditions Associated with Down syndrome
3.7. Symptoms of Down syndrome
3.8. Risk factors for Down syndrome
3.9. Genetics Basis of Down syndrome
3.9.1. Gene expression variation
3.10. Diagnosis of Down syndrome

4. Epidemiology and Patient Population
4.1. Key Findings
4.2. Total Diagnosed Prevalent Population of Down syndrome in 7MM

5. Country Wise-Epidemiology of Down syndrome
5.1. United States
5.1.1. Assumptions and Rationale
5.1.2. Total Diagnosed Prevalent Cases of Down syndrome in the United States
5.1.3. Type-Specific Diagnosed Prevalent Population of Down syndrome in the United States
5.1.4. Sex-Specific Diagnosed Prevalent Population of Down syndrome in the United States
5.1.5. Age-Specific Diagnosed Prevalent Population of Down syndrome in the United States
5.1.6. Diagnosed Prevalent Population of Down syndrome by Clinical Manifestation in the United States
5.2. EU5 Countries
5.3. Germany
5.3.1. Assumptions and Rationale
5.3.2. Total Diagnosed Prevalent Cases of Down syndrome in Germany
5.3.3. Type-Specific Diagnosed Prevalent Population of Down syndrome in Germany
5.3.4. Sex-Specific Diagnosed Prevalent Population of Down syndrome in Germany
5.3.5. Age-Specific Diagnosed Prevalent Population of Down syndrome in Germany
5.3.6. Diagnosed Prevalent Population of Down syndrome by Clinical Manifestation in Germany

6. France
6.1.1. Assumptions and Rationale
6.1.2. Total Diagnosed Prevalent Cases of Down syndrome in France
6.1.3. Type-Specific Diagnosed Prevalent Population of Down syndrome in France
6.1.4. Sex-Specific Diagnosed Prevalent Population of Down syndrome in France
6.1.5. Age-Specific Diagnosed Prevalent Population of Down syndrome in France
6.1.6. Diagnosed Prevalent Population of Down syndrome by Clinical Manifestation in France
6.2. Italy
6.2.1. Assumptions and Rationale
6.2.2. Total Diagnosed Prevalent Cases of Down syndrome in Italy
6.2.3. Type-Specific Diagnosed Prevalent Population of Down syndrome in Italy
6.2.4. Sex-Specific Diagnosed Prevalent Population of Down syndrome in Italy
6.2.5. Age-Specific Diagnosed Prevalent Population of Down syndrome in Italy
6.2.6. Diagnosed Prevalent Population of Down syndrome by Clinical Manifestation in Italy
6.3. Spain
6.3.1. Assumptions and Rationale
6.3.2. Total Diagnosed Prevalent Cases of Down syndrome in Spain
6.3.3. Type-Specific Diagnosed Prevalent Population of Down syndrome in Spain
6.3.4. Sex-Specific Diagnosed Prevalent Population of Down syndrome in Spain
6.3.5. Age-Specific Diagnosed Prevalent Population of Down syndrome in Spain
6.3.6. Diagnosed Prevalent Population of Down syndrome by Clinical Manifestation in Spain
6.4. United Kingdom
6.4.1. Assumptions and Rationale
6.4.2. Total Diagnosed Prevalent Cases of Down syndrome in the UK
6.4.3. Type-Specific Diagnosed Prevalent Population of Down syndrome in the UK
6.4.4. Sex-Specific Diagnosed Prevalent Population of Down syndrome in the UK
6.4.5. Age-Specific Diagnosed Prevalent Population of Down syndrome in the UK
6.4.6. Diagnosed Prevalent Population of Down syndrome by Clinical Manifestation in the UK
6.5. Japan
6.5.1. Assumptions and Rationale
6.5.2. Total Diagnosed Prevalent Cases of Down syndrome in Japan
6.5.3. Type-Specific Diagnosed Prevalent Population of Down syndrome in Japan
6.5.4. Sex-Specific Diagnosed Prevalent Population of Down syndrome in Japan
6.5.5. Age-Specific Diagnosed Prevalent Population of Down syndrome in Japan
6.5.6. Diagnosed Prevalent Population of Down syndrome by Clinical Manifestation in Japan

7. Current Treatment Practices
7.1. Management Guidelines
7.1.1. American College of Obstetricians and Gynecologists
7.1.2. Health Care Guidelines for People with Down syndrome: European Down Syndrome Association

8. Unmet needs

9. Emerging Therapies
9.1. Key Cross Competition
9.2. Aricept: Eisai
9.2.1. Product Description
9.2.2. Other Developmental Activities
9.2.3. Clinical Development
9.2.4. Clinical Trials Information
9.2.5. Product Profile
9.3. ELND005: Transition Therapeutics Ireland Limited
9.3.1. Product Description
9.3.2. Other Developmental Activities
9.3.3. Clinical Development
9.3.4. Clinical Trials Information
9.3.5. Safety and Efficacy
9.3.6. Product Profile
9.4. Pentylenetetrazole: Balance Therapeutics
9.4.1. Product Description
9.4.2. Other Developmental Activities
9.4.3. Clinical Development
9.4.4. Clinical Trials Information
9.4.5. Product Profile
9.5. ACI-24: AC Immune
9.5.1. Product Description
9.5.2. Other Developmental Activities
9.5.3. Clinical Development
9.5.4. Clinical Trials Information
9.5.5. Safety and Efficacy
9.5.6. Product Profile

10. Down syndrome: 7 Major Market Analysis
10.1. Key Findings
10.2. Market Size of Down syndrome in 7MM

11. The United States Market Outlook
11.1. United States Market Size
11.1.1. Total Market size of Down syndrome in the United States
11.2. EU-5 Countries: Market Outlook
11.3. Germany
11.3.1. Total Market size of Down syndrome in Germany
11.4. France
11.4.1. Total Market Size of Down Syndrome in France
11.5. Italy
11.5.1. Total Market Size of Down Syndrome in Italy
11.6. Spain
11.6.1. Total Market size of Down syndrome in Spain
11.7. United Kingdom
11.7.1. Total Market Size of Down Syndrome in the United Kingdom

12. Japan: Market Outlook
12.1. Japan
12.1.1. Total Market Size of Down Syndrome in Japan

13. Market Drivers

14. Market Barriers

15. Appendix
15.1. Report Methodology

16. The Publisher's Capabilities

17. Disclaimer

18. About the Publisher
Note: Product cover images may vary from those shown
  • Eisai
  • Transition Therapeutics Ireland Limited
  • Balance Therapeutics
  • AC Immune
Note: Product cover images may vary from those shown
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