The Isothermal Nucleic Acid Amplification Technology (INAAT) Market is expected to register a CAGR of 11.1% during the forecast period. Increasing incidences of chronic diseases and aging population, increase in the adoption of INAAT over PCR, and rise in demand for low-cost and effective diagnostics procedures are some of the major factors that are driving the growth of the market studied.
Nucleic acid amplification has several applications in the healthcare industry starting from research to clinics. Until now, PCR has been the most widely-used amplification technology across the world. A thermal cycler is required in PCR, as various temperatures need to be maintained at different steps of the amplification process. Additionally, contaminants must be removed for effective amplification through this technology. The thermal cycler itself is costly, and sample preparation to remove contaminants from the sample makes the overall process more costly and time-consuming.
Owing to this high cost, the technique has witnessed limited adoption in developing countries, where the demand for this technology is extremely high, especially for clinical application. This high demand has led to the development of novel innovative techniques, such as isothermal nucleic acid amplification technology.
According to the World Health Organization (WHO), estimated that in 2020, chronic diseases will account for almost three-quarters of all deaths worldwide. In addition 71% of deaths will be due to ischaemic heart disease (IHD), 75% of deaths due to stroke, and 70% of deaths due to diabetes will occur in developing countries.
The isothermal technique, as the name suggests, is performed at a fixed temperature. This temperature can vary depending on the type of nucleic acid. The tedious task of preparing a sample is not required, as the technology can take a sample directly for amplification. Additionally, the technology is affordable, making it accessible for people belonging to different economic levels across the world. The low-cost associated with technology is likely to result in increased adoption, especially in the developing regions.
Hence, owing to the cost benefits and the use of novel technologies, INAAT market is expected to grow in the coming future.
Key Market Trends
Loop-mediated Isothermal Amplification (LAMP) Segment is Expected to Hold a Major Market Share in the Isothermal Nucleic Acid Amplification Technology (INAAT) Market
Loop-mediated isothermal amplification (LAMP) test is the most widely used technique, and its usage is expected to grow rapidly during the forecast period. In this technique, a minimum of four sets of primers are used, two outer primers and two inner primers. There are various software's that are available for primer designing, such as primer explorer, LAMP designer, and other software. These loop primers bind to the nucleic acid template and further accelerate the reaction. The technique can be used for amplification of both, DNA and RNA.
Since its inception in the early 2000s, LAMP tests have been developed for a variety of disease-causing agents, due to its capability of amplifying both DNA and RNA. Additionally, the tests can be used for the identification of genetically modified organisms.
This technique has two major competitive advantages over the PCR technology. First, the LAMP test is tolerant of PCR inhibitors, which makes it well-suited for direct analysis of the sample. Secondly, there is no need of thermocycler, as it is performed at a fixed temperature. These two advantages make it useful in point-of-care diagnostics. As the market for point-of-care diagnostics is growing, the LAMP segment of the market studied is also likely to grow proportionally.
According to World Ageing 2019 report, estimated that there were about 703 million people aged 65 years or over in the world in 2019. This number is projected to double to 1.5 billion in 2050. In addition, by 2050, 1 in 6 people in the world will be above 65 years of age, up from 1 in 11 in 2019. Thus, owing to above all factors segment is expected to show growth over forecast period.
North America is Expected to Hold a Significant Share in the Market and Expected to do Same in the Forecast Period
North America dominates the Isothermal Nucleic Acid Amplification Technology (INAAT) market, owing to a high incidence of chronic diseases, technological advancement in isothermal nucleic acid amplification technology (INAAT), and increasing adoption of INAAT over conventional techniques in the region.
According to the Centers for Disease Control and Prevention (CDC), in 2020, the total number of Americans with chronic diseases was projected to be approximately 157 million, with 81 million having multiple conditions. The Asia Pacific is expected to grow during the forecast period, owing to factors, such as high demand in cost-effective and diagnostics, less stringent regulatory scenario, and the presence of a huge population base.
Competitive Landscape
The Isothermal Nucleic Acid Amplification Technology (INAAT) Market is consolidated competitive and consists of global players such as Becton Dickinson and Company, Qiagen NV, bioMerieux, etc. With the rising use of INAA Technology across the developing countries, it is expected that few local players in countries like China, India, etc. will penetrate the market in the near future. However, the largest share of this market is grabbed by the global players as of now.
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Nucleic acid amplification has several applications in the healthcare industry starting from research to clinics. Until now, PCR has been the most widely-used amplification technology across the world. A thermal cycler is required in PCR, as various temperatures need to be maintained at different steps of the amplification process. Additionally, contaminants must be removed for effective amplification through this technology. The thermal cycler itself is costly, and sample preparation to remove contaminants from the sample makes the overall process more costly and time-consuming.
Owing to this high cost, the technique has witnessed limited adoption in developing countries, where the demand for this technology is extremely high, especially for clinical application. This high demand has led to the development of novel innovative techniques, such as isothermal nucleic acid amplification technology.
According to the World Health Organization (WHO), estimated that in 2020, chronic diseases will account for almost three-quarters of all deaths worldwide. In addition 71% of deaths will be due to ischaemic heart disease (IHD), 75% of deaths due to stroke, and 70% of deaths due to diabetes will occur in developing countries.
The isothermal technique, as the name suggests, is performed at a fixed temperature. This temperature can vary depending on the type of nucleic acid. The tedious task of preparing a sample is not required, as the technology can take a sample directly for amplification. Additionally, the technology is affordable, making it accessible for people belonging to different economic levels across the world. The low-cost associated with technology is likely to result in increased adoption, especially in the developing regions.
Hence, owing to the cost benefits and the use of novel technologies, INAAT market is expected to grow in the coming future.
Key Market Trends
Loop-mediated Isothermal Amplification (LAMP) Segment is Expected to Hold a Major Market Share in the Isothermal Nucleic Acid Amplification Technology (INAAT) Market
Loop-mediated isothermal amplification (LAMP) test is the most widely used technique, and its usage is expected to grow rapidly during the forecast period. In this technique, a minimum of four sets of primers are used, two outer primers and two inner primers. There are various software's that are available for primer designing, such as primer explorer, LAMP designer, and other software. These loop primers bind to the nucleic acid template and further accelerate the reaction. The technique can be used for amplification of both, DNA and RNA.
Since its inception in the early 2000s, LAMP tests have been developed for a variety of disease-causing agents, due to its capability of amplifying both DNA and RNA. Additionally, the tests can be used for the identification of genetically modified organisms.
This technique has two major competitive advantages over the PCR technology. First, the LAMP test is tolerant of PCR inhibitors, which makes it well-suited for direct analysis of the sample. Secondly, there is no need of thermocycler, as it is performed at a fixed temperature. These two advantages make it useful in point-of-care diagnostics. As the market for point-of-care diagnostics is growing, the LAMP segment of the market studied is also likely to grow proportionally.
According to World Ageing 2019 report, estimated that there were about 703 million people aged 65 years or over in the world in 2019. This number is projected to double to 1.5 billion in 2050. In addition, by 2050, 1 in 6 people in the world will be above 65 years of age, up from 1 in 11 in 2019. Thus, owing to above all factors segment is expected to show growth over forecast period.
North America is Expected to Hold a Significant Share in the Market and Expected to do Same in the Forecast Period
North America dominates the Isothermal Nucleic Acid Amplification Technology (INAAT) market, owing to a high incidence of chronic diseases, technological advancement in isothermal nucleic acid amplification technology (INAAT), and increasing adoption of INAAT over conventional techniques in the region.
According to the Centers for Disease Control and Prevention (CDC), in 2020, the total number of Americans with chronic diseases was projected to be approximately 157 million, with 81 million having multiple conditions. The Asia Pacific is expected to grow during the forecast period, owing to factors, such as high demand in cost-effective and diagnostics, less stringent regulatory scenario, and the presence of a huge population base.
Competitive Landscape
The Isothermal Nucleic Acid Amplification Technology (INAAT) Market is consolidated competitive and consists of global players such as Becton Dickinson and Company, Qiagen NV, bioMerieux, etc. With the rising use of INAA Technology across the developing countries, it is expected that few local players in countries like China, India, etc. will penetrate the market in the near future. However, the largest share of this market is grabbed by the global players as of now.
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Table of Contents
1 INTRODUCTION
4 MARKET DYNAMICS
5 MARKET SEGMENTATION
6 COMPETITIVE LANDSCAPE
Companies Mentioned (Partial List)
A selection of companies mentioned in this report includes, but is not limited to:
- Becton, Dickinson & Company
- BioMerieux SA
- Eiken Chemical Co. Ltd
- Lucigen
- Meridian Bioscience
- Tecan Genomics Inc.
- OptiGene Limited
- Qiagen NV
- Quidel Corporation
Methodology
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