Upsher-Smith Laboratories is a family-owned, privately-held pharmaceutical company, based in the Midwest of the United States. It specializes in therapies and solutions for people living with central nervous system (CNS) conditions, such as seizure disorders. It also offers drugs for dermatology and heart health, and for conditions including epilepsy, spasticity, schizophrenia, bipolar disorder, hypertension, and bladder instability. Founded in 1919, the company is headquartered in Maple Grove, Minnesota.