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Global Cryo-electron Microscopy Market by Technology (Nuclear Magnetic Resonance (NMR) Microscopy, Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM)), Product (Instruments, Services, Software), Voltage, Application, End-User - Forecast 2024-2030

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  • 194 Pages
  • March 2024
  • Region: Global
  • 360iResearch™
  • ID: 5788856
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The Cryo-electron Microscopy Market size was estimated at USD 1.23 billion in 2023, USD 1.37 billion in 2024, and is expected to grow at a CAGR of 10.74% to reach USD 2.52 billion by 2030.

Cryo-electron microscopy (cryo-EM) is used to visualize the 3D structure of biological macromolecules at high resolution and has revolutionized structural biology by providing detailed insights into the shapes and functions of biomolecules such as proteins, nucleic acids, and complexes. In cryo-EM, samples are rapidly frozen in a thin layer of vitreous ice, which preserves their native state and prevents the formation of crystalline structures or other artifacts. The frozen samples are imaged using an electron microscope at cryogenic temperatures (typically around -180°C). The rising need for cryo-EM in structural biology to develop 3D structures of biomacromolecules and the increasing use of cryo-electron microscopy in drug discovery & development raised the adoption of cryo-electron microscopy. However, the requirement of huge capital for equipment purchase of cryo-electron microscopy and the lack of skilled professional experts significantly impedes the utilization of cryo-electron microscopy. In addition, emerging technological advancements in cryo-electron microscopes and ongoing funding and investments from private and public for cryo-EM installations are expected to create tremendous opportunities for developing the cryo-electron microscopy market.

Regional Insights

In North America, the increasing research in the development of nanotechnology, rising technological advancements in microscopy, growing research & development investments, and the launch of new products are boosting the adoption of cryo-electron microscopy. In October 2022, Thermo Fisher Scientific launched the Glacios 2 Cryo-Transmission Electron Microscope (Cryo-TEM), which features high-resolution capabilities and helps research drug discovery. In the Asia-Pacific, especially in India and China, the presence of various research institutes and therapeutic studies and the market players are focusing on expanding their manufacturing capabilities, significantly increasing the installation of cryo-electron microscopes. In Europe, governments and multiple technology firms focus on developing nanotechnology due to its rise in numerous applications and are investing in cryo-electron microscope technology. The cryo-electron microscope market in this region is expanding due to an increase in several well-equipped diagnostic centers and ongoing clinical trials.

FPNV Positioning Matrix

The FPNV Positioning Matrix is pivotal in evaluating the Cryo-electron Microscopy Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).

Market Share Analysis

The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Cryo-electron Microscopy Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.

Key Company Profiles

The report delves into recent significant developments in the Cryo-electron Microscopy Market, highlighting leading vendors and their innovative profiles. These include AstraZeneca PLC, ATEM Structural Discovery, Carl Zeiss AG, Charles River Laboratories International, Inc., Creative Biostructure, Delmic B.V., Delong America Inc., Electron Microscopy Sciences, EMphasis, Gandeeva Therapeutics, Inc., Gatan, Inc., Hitachi High-Tech Corporation, Intertek Group PLC, Jena Bioscience GmbH, Jeol Ltd., LeadXpro AG, Leica Microsystems by Danaher Corporation, Linkam Scientific Instruments Ltd., NanoImaging Services, Inc., NovAliX, Oxford Instruments by Spectris PLC, Proteros biostructures GmbH, Protochips, Inc., Quorum Technologies by Judges Scientific PLC, Shuimu BioSciences Ltd., SPT Labtech Ltd., Structura Biotechnology Inc., Thermo Fisher Scientific Inc., and Wuxi Biortus Biosciences Co. Ltd.

Market Segmentation & Coverage

This research report categorizes the Cryo-electron Microscopy Market to forecast the revenues and analyze trends in each of the following sub-markets:

  • Technology
    • Nuclear Magnetic Resonance (NMR) Microscopy
    • Scanning Electron Microscopy (SEM)
    • Transmission Electron Microscopy (TEM)
  • Product
    • Instruments
      • Fully Automated Instruments
      • Semi Automated Instruments
    • Services
    • Software
  • Voltage
    • 120 KV
    • 200 KV
    • 300 KV
  • Application
    • Biological Science
    • Lifesciences
    • Material Science
    • Nanotechnology
    • Semiconductor
  • End-User
    • Contract Research Organization
    • Forensic & Diagnostic Laboratories
    • Pharmaceutical & Biotechnology Companies
    • Research Laboratories & Institutes
  • Region
    • Americas
      • Argentina
      • Brazil
      • Canada
      • Mexico
      • United States
        • California
        • Florida
        • Illinois
        • New York
        • Ohio
        • Pennsylvania
        • Texas
    • Asia-Pacific
      • Australia
      • China
      • India
      • Indonesia
      • Japan
      • Malaysia
      • Philippines
      • Singapore
      • South Korea
      • Taiwan
      • Thailand
      • Vietnam
    • Europe, Middle East & Africa
      • Denmark
      • Egypt
      • Finland
      • France
      • Germany
      • Israel
      • Italy
      • Netherlands
      • Nigeria
      • Norway
      • Poland
      • Qatar
      • Russia
      • Saudi Arabia
      • South Africa
      • Spain
      • Sweden
      • Switzerland
      • Turkey
      • United Arab Emirates
      • United Kingdom

The report offers valuable insights on the following aspects

  1. Market Penetration: It presents comprehensive information on the market provided by key players.
  2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
  3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
  4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
  5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.

The report addresses key questions such as

  1. What is the market size and forecast of the Cryo-electron Microscopy Market?
  2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Cryo-electron Microscopy Market?
  3. What are the technology trends and regulatory frameworks in the Cryo-electron Microscopy Market?
  4. What is the market share of the leading vendors in the Cryo-electron Microscopy Market?
  5. Which modes and strategic moves are suitable for entering the Cryo-electron Microscopy Market?

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Table of Contents

1. Preface
1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Limitations
1.7. Assumptions
1.8. Stakeholders
2. Research Methodology
2.1. Define: Research Objective
2.2. Determine: Research Design
2.3. Prepare: Research Instrument
2.4. Collect: Data Source
2.5. Analyze: Data Interpretation
2.6. Formulate: Data Verification
2.7. Publish: Research Report
2.8. Repeat: Report Update
3. Executive Summary
4. Market Overview
4.1. Introduction
4.2. Cryo-electron Microscopy Market, by Region
5. Market Insights
5.1. Market Dynamics
5.1.1. Drivers
5.1.1.1. Rising need in structural biology to develop 3D structures of biomacromolecules
5.1.1.2. Burgeoning use of cryo-electron microscopy in drug discovery and development
5.1.1.3. Increasing focus on nanotechnology in healthcare and life science field
5.1.2. Restraints
5.1.2.1. Requirement of large capital for equipment purchase of cryo-electron microscopy
5.1.3. Opportunities
5.1.3.1. Emerging technological advancements in cryo-electron microscopes
5.1.3.2. Potential fundings and investments from private and public for cryo-EM installations
5.1.4. Challenges
5.1.4.1. Dearth of skilled professional experts and presence of rigorous norms and regulation
5.2. Market Segmentation Analysis
5.3. Market Trend Analysis
5.4. Cumulative Impact of High Inflation
5.5. Porter’s Five Forces Analysis
5.5.1. Threat of New Entrants
5.5.2. Threat of Substitutes
5.5.3. Bargaining Power of Customers
5.5.4. Bargaining Power of Suppliers
5.5.5. Industry Rivalry
5.6. Value Chain & Critical Path Analysis
5.7. Regulatory Framework
6. Cryo-electron Microscopy Market, by Technology
6.1. Introduction
6.2. Nuclear Magnetic Resonance (NMR) Microscopy
6.3. Scanning Electron Microscopy (SEM)
6.4. Transmission Electron Microscopy (TEM)
7. Cryo-electron Microscopy Market, by Product
7.1. Introduction
7.2. Instruments
7.3.1. Fully Automated Instruments
7.3.2. Semi Automated Instruments
7.3. Services
7.4. Software
8. Cryo-electron Microscopy Market, by Voltage
8.1. Introduction
8.2. 120 KV
8.3. 200 KV
8.4. 300 KV
9. Cryo-electron Microscopy Market, by Application
9.1. Introduction
9.2. Biological Science
9.3. Lifesciences
9.4. Material Science
9.5. Nanotechnology
9.6. Semiconductor
10. Cryo-electron Microscopy Market, by End-User
10.1. Introduction
10.2. Contract Research Organization
10.3. Forensic & Diagnostic Laboratories
10.4. Pharmaceutical & Biotechnology Companies
10.5. Research Laboratories & Institutes
11. Americas Cryo-electron Microscopy Market
11.1. Introduction
11.2. Argentina
11.3. Brazil
11.4. Canada
11.5. Mexico
11.6. United States
12. Asia-Pacific Cryo-electron Microscopy Market
12.1. Introduction
12.2. Australia
12.3. China
12.4. India
12.5. Indonesia
12.6. Japan
12.7. Malaysia
12.8. Philippines
12.9. Singapore
12.10. South Korea
12.11. Taiwan
12.12. Thailand
12.13. Vietnam
13. Europe, Middle East & Africa Cryo-electron Microscopy Market
13.1. Introduction
13.2. Denmark
13.3. Egypt
13.4. Finland
13.5. France
13.6. Germany
13.7. Israel
13.8. Italy
13.9. Netherlands
13.10. Nigeria
13.11. Norway
13.12. Poland
13.13. Qatar
13.14. Russia
13.15. Saudi Arabia
13.16. South Africa
13.17. Spain
13.18. Sweden
13.19. Switzerland
13.20. Turkey
13.21. United Arab Emirates
13.22. United Kingdom
14. Competitive Landscape
14.1. FPNV Positioning Matrix
14.2. Market Share Analysis, By Key Player
14.3. Competitive Scenario Analysis, By Key Player
14.3.1. Merger & Acquisition
14.3.1.1. Protochips Announces the Acquisition of the C-Flat and Au-flat Product Lines by Electron Microscopy Sciences (EMS).
14.3.2. Agreement, Collaboration, & Partnership
14.3.2.1. Gandeeva and Moderna Enter into Cryo-EM Research Collaboration to Explore Protein Surface Structure at Atomic Resolution.
14.3.2.2. Thermo Fisher Scientific and Structura Biotechnology Collaborate To Offer a Solution for Real-Time Cryo-EM Data Analysis.
14.3.3. New Product Launch & Enhancement
14.3.3.1. JEOL: Launch of the FIB-SEM System “JIB-PS500i” with High Precision and High Resolution.
14.3.3.2. Thermo Fisher Scientific Announces New Cryo-TEM With Expansive Automation Features To Help Accelerate Drug Discovery Research.
14.3.3.3. Thermo Fisher Launches New Automated Cryo-PFIB Microscope.
14.3.3.4. Thermo Fisher’s Cryo-Electron Microscopy Solutions to help in structural biology research at CCMB.
14.3.4. Investment & Funding
14.3.4.1. ByteDance Invests in the Cryo-EM & AI Powered Biotech Startup Shuimu BioSciences.
14.3.5. Award, Recognition, & Expansion
14.3.5.1. ATEM Structural Discovery Announces Opening of a Cryo-EM lab in Germany.
15. Competitive Portfolio
15.1. Key Company Profiles
15.1.1. AstraZeneca PLC
15.1.2. ATEM Structural Discovery
15.1.3. Carl Zeiss AG
15.1.4. Charles River Laboratories International, Inc.
15.1.5. Creative Biostructure
15.1.6. Delmic B.V.
15.1.7. Delong America Inc.
15.1.8. Electron Microscopy Sciences
15.1.9. EMphasis
15.1.10. Gandeeva Therapeutics, Inc.
15.1.11. Gatan, Inc.
15.1.12. Hitachi High-Tech Corporation
15.1.13. Intertek Group PLC
15.1.14. Jena Bioscience GmbH
15.1.15. Jeol Ltd.
15.1.16. LeadXpro AG
15.1.17. Leica Microsystems by Danaher Corporation
15.1.18. Linkam Scientific Instruments Ltd.
15.1.19. NanoImaging Services, Inc.
15.1.20. NovAliX
15.1.21. Oxford Instruments by Spectris PLC
15.1.22. Proteros biostructures GmbH
15.1.23. Protochips, Inc.
15.1.24. Quorum Technologies by Judges Scientific PLC
15.1.25. Shuimu BioSciences Ltd.
15.1.26. SPT Labtech Ltd.
15.1.27. Structura Biotechnology Inc.
15.1.28. Thermo Fisher Scientific Inc.
15.1.29. Wuxi Biortus Biosciences Co. Ltd.
15.2. Key Product Portfolio
16. Appendix
16.1. Discussion Guide
16.2. License & Pricing
List of Figures
FIGURE 1. CRYO-ELECTRON MICROSCOPY MARKET RESEARCH PROCESS
FIGURE 2. CRYO-ELECTRON MICROSCOPY MARKET SIZE, 2023 VS 2030
FIGURE 3. CRYO-ELECTRON MICROSCOPY MARKET SIZE, 2018-2030 (USD MILLION)
FIGURE 4. CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY REGION, 2023 VS 2030 (%)
FIGURE 5. CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY REGION, 2023 VS 2024 VS 2030 (USD MILLION)
FIGURE 6. CRYO-ELECTRON MICROSCOPY MARKET DYNAMICS
FIGURE 7. CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY TECHNOLOGY, 2023 VS 2030 (%)
FIGURE 8. CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY TECHNOLOGY, 2023 VS 2024 VS 2030 (USD MILLION)
FIGURE 9. CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY PRODUCT, 2023 VS 2030 (%)
FIGURE 10. CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY PRODUCT, 2023 VS 2024 VS 2030 (USD MILLION)
FIGURE 11. CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY VOLTAGE, 2023 VS 2030 (%)
FIGURE 12. CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY VOLTAGE, 2023 VS 2024 VS 2030 (USD MILLION)
FIGURE 13. CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY APPLICATION, 2023 VS 2030 (%)
FIGURE 14. CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY APPLICATION, 2023 VS 2024 VS 2030 (USD MILLION)
FIGURE 15. CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY END-USER, 2023 VS 2030 (%)
FIGURE 16. CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY END-USER, 2023 VS 2024 VS 2030 (USD MILLION)
FIGURE 17. AMERICAS CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY COUNTRY, 2023 VS 2030 (%)
FIGURE 18. AMERICAS CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY COUNTRY, 2023 VS 2024 VS 2030 (USD MILLION)
FIGURE 19. UNITED STATES CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY STATE, 2023 VS 2030 (%)
FIGURE 20. UNITED STATES CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY STATE, 2023 VS 2024 VS 2030 (USD MILLION)
FIGURE 21. ASIA-PACIFIC CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY COUNTRY, 2023 VS 2030 (%)
FIGURE 22. ASIA-PACIFIC CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY COUNTRY, 2023 VS 2024 VS 2030 (USD MILLION)
FIGURE 23. EUROPE, MIDDLE EAST & AFRICA CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY COUNTRY, 2023 VS 2030 (%)
FIGURE 24. EUROPE, MIDDLE EAST & AFRICA CRYO-ELECTRON MICROSCOPY MARKET SIZE, BY COUNTRY, 2023 VS 2024 VS 2030 (USD MILLION)
FIGURE 25. CRYO-ELECTRON MICROSCOPY MARKET, FPNV POSITIONING MATRIX, 2023
FIGURE 26. CRYO-ELECTRON MICROSCOPY MARKET SHARE, BY KEY PLAYER, 2023

Companies Mentioned

  • AstraZeneca PLC
  • ATEM Structural Discovery
  • Carl Zeiss AG
  • Charles River Laboratories International, Inc.
  • Creative Biostructure
  • Delmic B.V.
  • Delong America Inc.
  • Electron Microscopy Sciences
  • EMphasis
  • Gandeeva Therapeutics, Inc.
  • Gatan, Inc.
  • Hitachi High-Tech Corporation
  • Intertek Group PLC
  • Jena Bioscience GmbH
  • Jeol Ltd.
  • LeadXpro AG
  • Leica Microsystems by Danaher Corporation
  • Linkam Scientific Instruments Ltd.
  • NanoImaging Services, Inc.
  • NovAliX
  • Oxford Instruments by Spectris PLC
  • Proteros biostructures GmbH
  • Protochips, Inc.
  • Quorum Technologies by Judges Scientific PLC
  • Shuimu BioSciences Ltd.
  • SPT Labtech Ltd.
  • Structura Biotechnology Inc.
  • Thermo Fisher Scientific Inc.
  • Wuxi Biortus Biosciences Co. Ltd.

Methodology

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