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Brain Stimulation, Vol 116. Handbook of Clinical Neurology

  • ID: 2336232
  • Book
  • 784 Pages
  • Elsevier Science and Technology
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The field of brain stimulation is expanding rapidly, with techniques such as DBS, TMS, and tDCS moving from the research community into clinical diagnosis and treatment. Clinical applications include treating disorders such as Parkinson's disease, dystonia, and even depression.

The chapters of Brain Stimulation are written by leading international researchers and clinical specialists include coverage of techniques, modes of action and applications in physiology and therapeutics. The combination of research and clinical coverage will be of interest to neurologists, neurosurgeons, psychiatrists, neuroscientists, and health care workers.

  • A comprehensive introduction and overview of deep brain stimulation (DBS)
  • Coverage of DBS, transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS)
  • Details the basic science and research utility of DBS and clinical application

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SECTION 1  Deep brain stimulation
Basic science
Principles of electrical stimulation of neural tissue; Deep brain stimulation in animal models; Deep brain stimulation surgical techniques; Deep brain stimulation: how does it work?; Computational modelling of deep brain stimulation; Therapeutic stimulation versus ablation; Magnetic resonance imaging safety of deep brain stimulator devices; Brain stimulation and functional imaging with fMRI and PET;
Clinical applications of deep brain stimulation
Deep brain stimulation for Parkinson disease: patient selection; Deep brain stimulation for Parkinson disease: clinical outcome; Postoperative management of deep brain stimulation in Parkinson disease; Psychiatric considerations in deep brain stimulation for Parkinson disease; Deep brain stimulation for essential tremor; Deep brain stimulation for dystonia; The role of deep brain stimulation in the treatment of secondary dystono-dyskinesia syndromes; Deep brain stimulation for other tremors, myoclonus and chorea; Deep brain stimulation for epilepsy; Deep brain stimulation for major depression; Deep brain stimulation in obsessive-compulsive disorder: neurocircuitry and clinical experience; Deep brain stimulation in Tourette syndrome; Deep brain stimulation in addiction due to psychoactive substance use;  Evaluating the potential of deep brain stimulation for treatment-resistant anorexia nervosa; Deep brain stimulation for pain; Central thalamic deep brain stimulation for support of forebrain arousal regulation in the minimally conscious state; Deep brain stimulation for cognitive disorders; Ethics guidance for neurological and psychiatric deep brain stimulation;
SECTION 2  Superficial brain stimulation
Basic principles
Transcranial electric and magnetic stimulation: technique and paradigms; Epidural and subdural stimulation; Physics of effects; Biology of effects
Clinical utility in diagnosis
Central motor conduction time; Pharmaco-TMS studies of motor excitability
Therapeutic uses
Treating the depressions with superficial brain stimulation methods; Other therapeutic psychiatric uses of superficial brain stimulation; Pain; Tinnitus; Parkinson disease; Dystonia; Epilepsy; Non-invasive brain stimulation in neurorehabilitation
Research applications
Plasticity; Research applications of non-invasive superficial brain stimulation in Parkinson disease; Transcranial magnetic stimulation in dystonia; Non-invasive brain stimulation in Huntington disease; Utility of transcranial magnetic stimulation in delineating ALS pathophysiology; Superficial brain stimulation in multiple sclerosis; Brain stimulation in migraine; Dementia; Addiction; Tourette syndrome; Cerebellum; Transcranial magnetic stimulation and vision; Transcranial magnetic stimulation techniques to study the somatosensory system: research applications
Language; Research applications of noninvasive brain stimulation: learning and memory; Cognition
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Lozano, Andres M.
Hallett, Mark
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