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Omega-3 Fatty Acids in Brain and Neurological Health

  • Book

  • October 2018
  • Elsevier Science and Technology
  • ID: 2496407

Research has clearly established a link between omega-3 fatty acids and general health, particularly cardiovascular health. Omega-3 Fatty Acids in Brain and Neurological Health is the first book to focus exclusively on the role of omega-3 fatty acids on general brain health. The articles in this collection illustrate omega-3 fatty acids' importance in longevity, cognitive impairment, and structure and function of the brain's neurons.

Research has established links between omega-3 fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis. This book encompasses some of the most recent research, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep, and neurodegenerative diseases. This collection helps to push research forward toward a complete understanding of omega-3 fatty acids' relationship to brain and neurological health.

Table of Contents

I: Overview of Neurological Changes: Targets for Dietary Omega-3 Fatty Acids 1. Enhanced longevity and role of omega-3 fatty acids 2. Molecular gerontology: Principles and perspectives for interventions 3. Peroxisomal pathways, their role in neurodegenerative disorders and therapeutic strategies 4. Unregulated lipid preoxidation in neurological dysfunction 5. Obesity, Western diet intake, and cognitive impairment 6. Genetic risk factors for diabetic neuropathy 7. n-3 fatty acid-derived lipid mediators against neurological oxidative stress and neuroinflammation 8. The impact of omega-3 fatty acids on quality of life

II: Fatty Acids and Brain 9. Mammalian fatty acid amides of the brain and CNS 10. Low omega-3 fatty acids diet and the impact on the development of visual connections and critical periods of plasticity 11. The effects of omega-3 polyunsaturated fatty acids on maternal and child mental health; 12. Pain as modified by polyunsaturated fatty acids 13. Fish oil supplementation prevents age-related memory decline: Involvement of nuclear hormone receptors 14. Role of omega 3 fatty acids in brain and neurological health with special reference to clinical depression 15. Omega 3 fatty acid supplementation for major depression with chronic disease 16. The effectiveness of fish oil as a treatment for ADHD 17. Fatty acids and the aging brain 18. Cerebrovascular changes: The role of fat and obesity 19. The role of omega-3 fatty acids on Alzheimer's disease

III: Omega-3 Fatty Acids and Structural Changes in Neuronal Tissues 20. Substantia nigra modulation by essential fatty acids 21. The role of omega-3 fatty acids in hippocampal neurogenesis 22. Imaging brain DHA metabolism in vivo, in animals and humans

IV: Fatty Acids in Brain and Neurological Function in Infants and Children 23. Obesity and migraine in children 24. Dietary omega-3 sources during pregnancy and the developing brain: Lessons from studies in rats

V: Fatty Acids and Neurological Outcomes 25. Omega-3 fatty acids and cognitive behavior 26. Lipid and lipid signaling in Drosophila models of neurodegenerative diseases 27. Polyunsaturated fatty acids in relation to sleep quality and depression in obstructive sleep apnea hypopnea syndrome 28. Omega-3 fatty acids in intellectual disability, schizophrenia, depression, autism and attention-deficit hyperactivity disorders 29. Effect of omega 3 fatty acids on aggression 30. Multiple sclerosis: Modification of fish oil 31. Deuterium protection of polyunsaturated fatty acids against lipid peroxidation: A novel approach to mitigating mitochondrial neurological diseases

VI: Dietary Fats, Obesity and Adverse Neurological Effects 32. Obesity, cognitive function and dementia: A life-span prospective 33. Dairy products and cognitive functions 34. Obesity and chronic low back pain: A kinematic approach 35. Fatty acids and the hippocampus

VII: Contaminants and Removal from Fish Oils 36. Fish oil supplements, contaminants, excessive doses 37. Introduction to fish oil oxidation, oxidation prevention and oxidation correction

Authors

Ronald Ross Watson Professor, Mel and Enid Zuckerman College of Public Health and School of Medicine, Arizona Health Sciences Center, University of Arizona, Tucson, AZ, USA. Ronald Ross Watson, PhD, is Professor of Health Promotion Sciences at the University of Arizona, Mel and Enid Zuckerman College of Public Health. Dr. Watson began his research in public health at the Harvard School of Public Health as a Fellow in 1971 doing field work on vaccines in Saudi Arabia. He has done clinical studies in Colombia, Iran, Egypt, Saudi Arabia and the United States which provides a broad international view of public health. He has served in the military reserve hospital for 17 years with extensive training in medical responses to disasters as the chief biochemistry officer of a general hospital, retiring as a Lt. Colonel. He is a distinguished member of several national and international nutrition, immunology, and cancer societies. Dr. Watson's career has involved studying many lifestyle aspects for their uses in health promotion. He has edited over 100 biomedical reference books and 450 papers and chapters. His teaching and research focuses on alcohol, tobacco, and drugs of abuse in heart function and disease in mouse models.