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Green Synthetic Approaches for Biologically Relevant Heterocycles

  • ID: 2986222
  • Book
  • October 2018
  • 632 Pages
  • Elsevier Science and Technology
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Green Synthetic Approaches for Biologically Relevant Heterocycles reviews this significant group of organic compounds within the context of sustainable methods and processes. Each clearly structured chapter features in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles classified on the basis of ring-size and/or presence of heteratoms(s). Techniques covered include microwave heating, ultrasound, ionic liquids, solid phase, solvent-free, heterogeneous catalysis, and aqueous media, along with multi-component reaction strategies. This book also integrates advances in green chemistry research into industrial applications and process developments. Green Synthetic Approaches for Biologically Relevant Heterocycles is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in medicinal, organic, natural product, and agricultural chemistry.

  • Includes global coverage of a wide variety of green synthetic techniques
  • Features cutting-edge research in the field of bioactive heterocyclic compounds
  • Focuses extensively on applications, with numerous examples of biologically relevant heterocycles
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1. Green synthetic approaches for biologically relevant heterocycles: An overview 2. Synthesis of bioactive five- and six-membered heterocycles catalyzed by heterogeneous supported metals 3. Transition-metal-free synthesis of benzo-fused five- and six-membered heterocycles employing arynes 4. Metal-catalyzed routes for the synthesis of furocoumarins and coumestans 5. Green solvents for eco-friendly synthesis of bioactive heterocyclic compounds 6. Green catalytic synthesis of heterocyclic structures using carbon dioxide and related motifs 7. Synthetic approaches to small and medium size aza-heterocycles in aqueous media 8. Green synthetic approaches for biologically relevant 2-amino-4H-pyrans and 2-amino-4H-pyran-annulated heterocycles in aqueous media 9. Sustainable synthesis of benzimidazoles, quinoxalines and congeners 10. Green and catalytic methods for ?-lactone synthesis 11. Green synthetic approaches for medium ring-sized heterocycles of biological interest 12. Organocatalyzed Biginelli reactions: A greener chemical approach for the synthesis of biologically active 3,4-dihydropyrimidin-2(1H)-ones/-thiones 13. Photocatalytic Minisci reaction: A promising and eco-friendly route to functionalize heteroaromatics of biological interest 14. Organo hypervalent iodine reagents in the synthesis of bioactive heterocycles 15. Porous catalytic systems in the synthesis of bioactive heterocycles and related compounds 16. High pressure cycloaddition reactions in the synthesis of biologically relevant heterocycles 17. Ionic liquids prompted synthesis of biologically relevant five and six-membered heterocyclic skeletons: An update 18. Heterocycles-based ionic liquid-supported synthesis of small organic molecules 19. Microwave-induced synthesis of heterocycles of medicinal interests 20. Application of microwave irradiation in the synthesis of P-heterocycles 21. Use of ultrasound in the synthesis of heterocycles of medicinal interest

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Brahmachari, Goutam
Goutam Brahmachari is a professor of organic chemistry at Visva-Bharati, India, and teaches courses in organic chemistry, natural products chemistry, synthetic organic chemistry, and physical methods in organic chemistry. In addition to over 20 years of teaching and research experience, he is a Fellow of the Royal Society of Chemistry, a Who's Who in the World Listee, and a recipient of Academic Brilliance Award (2015) for Excellence in Research and the Dr. Kalam Best Teaching Faculty Award (2017). Prof. Brahmachari serves as journal referee, editor-in-chief, associate editor, guest editor, and Editorial Advisory Board Member for several international journals, book publishers, and research funding agencies. He currently has 200 publications in the fields of organic and medicinal chemistry, including 22 books and over 40 book chapters, published by internationally reputed publishers.
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